Exome Sequencing

About Linked Reads for Exome Sequencing

Reach Beyond the Standard Exome

The Chromium Exome provides long range information, enabling phasing, structural variant detection and copy number determination. Low complexity and repetitive regions previously missed with short-read sequencing are now accessible.

Benefits

  • High-quality libraries from only 1 ng of genomic DNA
  • Detect large scale structural variants (SVs) including gene fusions
  • Call and phase variants across the entire exome
  • Detect variants in genes inaccessible to standard short-read libraries
  • Useful for high sequence homology, including problematic duplications, inversions and pseudogenes
  • Optimized baits utilize Linked-Reads for intron-spanning

Workflow