Protein Cartridges

December 21, 2023/in BiOptic, Consumables, Partners/by Harshita Sharma

PRODUCTS

Protein Cartridges

P2 Protein Cartridge Kit

The cartridge analyzes protein sample size and purity with higher sensitivity and resolution.
The analysis size range is 11~155kDa but the detection range is up to 600kDa.
Qsep100 Advance is the recommended platform for detecting fluorescent-labeled protein sample.
Each cartridge can analyze 100 runs for single-channel cartridge or 400 runs for 4-channel cartridge.

Ready To Order?

Our team can help you in placing the order. Click below to get a quote and fast ordering.

BiOptic Consumables Portfolio

Have a question?

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

Or give us a call at:

1300 581 991

S2 Cartridge (Standard Cartridge) BiOptic

DNA Cartridges

December 21, 2023/in BiOptic, Consumables, Partners/by Harshita Sharma

PRODUCTS

DNA Cartridges

S2 Standard Cartridge Kit

S2 cartridge is for PCR products, small-sized DNA, and NGS quality control (Fragmentation and Library sample) analyses.
The analysis time is 2~3 minutes and the best resolution is 4~10bp if the sample size is less than 500bp.
It has a recommended size range up to around 5,000bp and a detection limit of about 0.1 ng/μl in low concentration.
Each cartridge can analyze 200 runs for single-channel cartridge or 800 runs for 4-channel cartridge.
The cartridge can be stored at 4~27°C and is valid for 6 months.

S1 High Resolution Cartridge Kit

The analysis time is 2~5 minutes and the best resolution is 1~4bp if the sample size is less than 500bp.
It provides high resolution result with multiple methods from low to high voltage (2~10kV) for user to choose from.
It has a recommended analysis range up to around 5,000bp and a detection limit of about 0.1 ng/μl in low concentration.
Each cartridge can analyze 200 runs for single-channel cartridge or 800 runs for 4-channel cartridge.
The cartridge can be stored at 4~27°C and is valid for 6 months.

S3 Kilobase Cartridge Kit

S3 cartridge is for large-sized DNA analysis.
It has a recommended 5~165kb size range and is ideal for quality control of second and third generation sequencing.
The system provides DNA Quality Number (DQN) for gDNA integrity reference.
Each cartridge can analyze 200 runs for single-channel cartridge or 800 runs for 4-channel cartridge.
The cartridge can be stored at 4~27°C and is valid for 6 months.

F3 Fast Cartridge Kit

The analysis time is 90 seconds and can be applied to PCR product analysis.
It has a recommended analysis range up to around 5,000bp for DNA.
It runs on Qsep100 and Qsep400 only.
Each cartridge can analyze 300 runs for single-channel cartridge or 1200 runs for 4-channel cartridge.
The cartridge can be stored at 4~27°C and is valid for 4 months.

N1 High Sensitivity Cartridge Kit

The sample concentration for analysis has a detection limit of about 5 pg/μl (or 1 pg/μl if dissolved in ddH2O) and the analysis time is about 3 minutes.
It can be used for analysis of low concentration DNA fragment and quality control of cell-free DNA.
It has a recommended analysis range up to around 5,000bp for DNA.
Each cartridge can analyze 100 runs for single-channel cartridge or 400 runs for 4-channel cartridge.
The cartridge can be stored at 4~27°C and is valid for 4 months.

N3 High Sensitivity Kilobase Cartridge Kit

N3 cartridge is for low concentration large-sized DNA analysis.
It has a recommended 5~165kb size range and is ideal for quality control of second and third generation sequencing.
The system provides DNA Quality Number (DQN) for gDNA integrity reference.
Each cartridge can analyze 200 runs for single-channel cartridge or 800 runs for 4-channel cartridge.
The cartridge can be stored at 4~27°C and is valid for 4 months.

Ready To Order?

Our team can help you in placing the order. Click below to get a quote and fast ordering.

BiOptic Consumables Portfolio

Have a question?

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

Or give us a call at:

1300 581 991

Qsep400

December 21, 2023/in BiOptic, Instruments, Partners/by Harshita Sharma

PRODUCTS

Qsep400

4-channel Bio-Fragment Analyzer designed for medium and large-sized labs, offering higher throughput and faster analysis.

Qsep400 features an integrated PC and touchscreen for user-friendly operation.

Capable of analyzing DNA, RNA, or protein with a 4~96 sample capacity.

Quantitative method provides comprehensive fragment size and concentration data in a single run.

Qsep400 is a high-throughput automated Bio-Fragment Analyzer. It is the highest specification product of Qsep series and can analyze hundreds of samples in one day. It supports various types of applications, including DNA, RNA and protein fragment analyses and high-voltage fast analysis. Advantages of capillary electrophoresis are high resolution (1~4bp if less than 500bp), high sensitivity (5pg/μl) and significantly faster preparation and analysis time. Besides analyzing the fragment sizes and concentrations, it is also a tool for quality control, and is best for NGS facilities and research centers.

Qsep400 is equipped with an integrated PC and touchscreen and can be directly controlled and analyzed. The system provides applications such as RNA quality control with RNA Quality Number (RQN) provided, auto-distribution of NGS QC and quality control of gDNA with DNA Quality Number (DQN) provided. Qsep400 is an independent and highly-efficient instrument.

Qsep series can not only replace the complicated and time-consuming gel preparation and analysis procedure, but increase the accuracy of analysis, elevate efficiency and reproducibility, and reduce the human error and costs.

Ready To Order?

Our team can help you in placing the order. Click below to get a quote and fast ordering.

BiOptic Instruments Portfolio

Have a question?

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

Or give us a call at:

1300 581 991

Qsep1-Plus

December 21, 2023/in BiOptic, Instruments, Partners/by Harshita Sharma

PRODUCTS

Qsep1-Plus

Smallest/portable-sized capillary electrophoresis Bio-Fragment Analyzer for DNA, RNA, and protein.

Qsep1-Plus is ideal for small laboratories with low throughput (1~15 samples) needs.

The system supports Wi-Fi and cable connections, breaking the barriers of space.

10+ types of cartridges can be easily exchanged between various applications.

The provided quantitative method delivers fragment size and concentration information in one run.

Qsep1-Plus has the highest specification product among all portable automated Bio-Fragment Analyzers. Advantages of capillary electrophoresis are high resolution (1~4bp if less than 500bp), high sensitivity (5pg/μl) and significantly faster preparation and analysis time. Besides analyzing fragment sizes and concentrations, it is also suitable for quality control of next-generation sequencing (NGS).

Qsep1-Plus is equipped with completed hardware and software and has fully functional remote access via cable/Wi-Fi. The system provides various kinds of applications such as RNA quality control with RNA Quality Number (RQN) provided, auto-distribution of NGS QC and quality control of gDNA with DNA Quality Number (DQN) provided. Qsep1-Plus is a top choice for modern small or medium-sized laboratory.

Qsep series can not only replace the complicated and time-consuming gel preparation and analysis procedure, but increase the accuracy of analysis, elevate efficiency and reproducibility, and reduce the human error and costs.

Ready To Order?

Our team can help you in placing the order. Click below to get a quote and fast ordering.

BiOptic Instruments Portfolio

Qsep100

Qsep1

Qsep400

Qsep1+

Qsep100 Advance

Have a question?

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

Or give us a call at:

1300 581 991

Qsep100

December 21, 2023/in BiOptic, Instruments, Partners/by Harshita Sharma

PRODUCTS

Qsep100

Standard-sized capillary electrophoresis Bio-Fragment Analyzer for DNA, RNA, and protein.

Ideal for small to medium-sized labs with 1~96 sample capacity.

Easily exchangeable cartridges for versatile applications.

Provides quantitative data on fragment size and concentration in a single run.

Efficient Bio-Fragment Analysis with Qsep100

The Qsep100, a standard-sized automated Bio-Fragment Analyzer, represents the classic model in the Qsep series. Boasting a single-channel design, it can seamlessly process 1 to 96 samples, making it an ideal choice for small and medium-sized laboratories. This high sample flexibility extends to various applications, including DNA, RNA, and protein fragment analyses, as well as high-voltage fast analysis.

Versatility for Various Applications

The Qsep100 supports a range of applications, offering RNA quality control with the provision of RNA Quality Number (RQN), automated distribution of NGS QC, and quality control of genomic DNA (gDNA) with the availability of DNA Quality Number (DQN). Particularly, it stands out as a top choice for Next-Generation Sequencing Quality Control (NGS QC).

Streamlining Processes and Enhancing Accuracy

The Qsep series, including the Qsep100, eliminates the need for intricate and time-consuming gel preparation and analysis procedures. This not only increases the accuracy of analysis but also elevates overall efficiency and reproducibility while reducing human errors and costs. Invest in Qsep100 for a seamless, reliable, and efficient bio-fragment analysis experience.

Ready To Order?

Our team can help you in placing the order. Click below to get a quote and fast ordering.

BiOptic Instruments Portfolio

Have a question?

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

Or give us a call at:

1300 581 991

Qsep1

December 21, 2023/in BiOptic, Instruments, Partners/by Harshita Sharma

PRODUCTS

Qsep1

Smallest/portable-sized capillary electrophoresis Bio-Fragment Analyzer for DNA, RNA, and protein.

Ideal for small laboratories with low throughput needs (1~8 samples).

Supports Wi-Fi and cable connections, enhancing spatial flexibility.

Easy exchange of 10+ cartridges between various applications.

Quantitative method provides fragment size and concentration info in a single run.

Qsep1 is an automated Bio-Fragment Analyzer for DNA, RNA and protein fragments. Advantages of capillary electrophoresis are high resolution (1~4bp if less than 500bp), high sensitivity (5pg/μl) and significantly faster preparation and analysis time. Besides analyzing fragment sizes and concentrations, it is also suitable for quality control of next-generation sequencing (NGS).

Qsep1 is equipped with completed hardware and software and has fully functional remote access via cable/Wi-Fi. The system provides various kinds of applications such as RNA quality control with RNA Quality Number (RQN) provided, auto-distribution of NGS QC and quality control of gDNA with DNA Quality Number (DQN) provided. Qsep1 is a top choice for modern small laboratory.

Qsep series can not only replace the complicated and time-consuming gel preparation and analysis procedure, but increase the accuracy of analysis, elevate efficiency and reproducibility, and reduce the human error and costs.

Ready To Order?

Our team can help you in placing the order. Click below to get a quote and fast ordering.

BiOptic Instruments Portfolio

Have a question?

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

Or give us a call at:

1300 581 991

Viral Controls

December 20, 2023/in Partners, Synthetic Controls, Twist/by Harshita Sharma

PRODUCTS

Synthetic Viral Controls

Trusted Controls for Diverse Applications

In the wake of the global demand for diagnostic tests amid the Coronavirus pandemic, laboratories worldwide seek reliable tools for detecting SARS-CoV-2 and Respiratory viruses across various sample types. Our controls offer a trusted solution to address the expanding need for testing, ensuring accuracy and safety in a wide range of applications.

Ensuring Reproducible, High-Quality Results

Positive controls play a pivotal role in maintaining quality standards for diagnostic assays, spanning from development to day-to-day testing. These controls facilitate the verification and validation of diagnostic tests, supporting both next-generation sequencing (NGS) and reverse transcription polymerase chain reaction (RT-PCR) assays, ensuring reproducibility and reliability.

Safe and Effective Alternatives to “Live Virus”

Concerns regarding safety and security associated with controls based on viral nucleic acids extracted from infected patients or live virus cultures led us to develop synthetic controls through gene synthesis. These alternatives offer a safe and effective solution, allowing broader access to diverse strains while mitigating potential risks.

Flexible Formulations for Varied Needs

Tailor your approach with our flexible control formulations—Standard, Assay Ready, or Encapsulated. Whether in a frozen liquid, dried pellet, or encapsulated dried pellet form, our controls provide options for shipping, storage, and stability, meeting the unique requirements of your applications. Ambient shipping reduces costs and enhances accessibility for researchers globally, making our controls a reliable choice in the dynamic landscape of diagnostic testing.

RESPIRATORY VIRUS CONTROLS

Comprehensive Controls for Respiratory Virus Research

Twist’s Synthetic Respiratory Virus Controls encompass a wide spectrum of RNA and DNA viruses crucial for respiratory disease studies. Aligned with the Twist Respiratory Virus Research Panel (PN 103067), these controls seamlessly integrate into Twist Fixed Panel NGS workflows, as well as RT-PCR or qPCR experiments designed by users.

Navigating the Viral Landscape

Refer to the taxonomic tree in the accompanying figure for a visual representation of the viruses covered by Twist Respiratory Virus Controls. The table provides GenBank IDs, virus types, and lengths for each control, facilitating an in-depth understanding of the viral landscape. Custom synthesis options are also available—connect with your local sales representative for additional details.

Simplify Your Research Journey

For further information or to make a purchase, contact your local sales representative or conveniently “Buy Now.” Twist’s Synthetic Respiratory Virus Controls offer a robust foundation for respiratory virus research, enhancing the precision and reliability of your experiments.

SARS-COV-2 CONTROLS

Elevating Quality Control with Twist Synthetic RNA Controls for SARS-CoV-2

Twist Bioscience offers synthetic RNA controls designed for diverse viral genomes, including SARS-CoV-2. With six non-overlapping 5 kb fragments transcribed into ssRNA, these controls provide over 99.9% genome coverage. Available in standard, Assay Ready, and Encapsulated Formats, they cater to various needs with concentrations tailored for flexibility.

Unique Stability in Encapsulated Controls

Twist’s Encapsulated Controls, sealed in a metal capsule around a desiccated pellet, ensure enhanced stability. With room temperature shipping and a five-year shelf life, these controls provide cost-effective and globally accessible solutions.

Contribution to Multiplex Assay Development

The Twist Assay Ready Synthetic SARS-CoV-2 RNA Control, developed with the US CDC, enables simultaneous testing for influenza A, B, and SARS-CoV-2. Originally designed for authorized laboratories, it is now available to customers outside the CDC.

Best Practices and Regulatory Considerations

For comprehensive guidance on storage and use of controls, refer to provided documents: Twist Assay Ready Synthetic Controls Storage and Use Document and Twist Sars-CoV-2 Encapsulated RNA Control Storage and Handling Guide.

Note: This product is authorized for emergency use by the FDA under an EUA for the detection of SARS-CoV-2 nucleic acid. The emergency use is limited to circumstances justifying the authorization.

MONKEYPOX CONTROLS

Twist Synthetic hMPXV Controls: Precision for Targeted Research

Twist’s Synthetic Human Monkeypox Virus (hMPXV) Controls, representing CB and WA clades, cover over 80% of the viral genome. Validated for custom assays and compatible with CDC-recommended PCR procedures, these controls, in two variants, offer precise tiling of the genome at 900bp intervals. With concentrations at approximately 100,000 copies/uL, they provide accuracy and reproducibility. Contact your local sales representative for more information.

Note: The Twist Synthetic hMPXV Controls are not ISO-13485 certified.

Ready To Order?

Our team can help you in placing the order. Click below to get a quote and fast ordering.

Synthetic Controls Portfolio

cfDNA Pan Cancer Reference standards

Viral
Controls

Have a question?

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

Or give us a call at:

1300 581 991

cfDNA Pan-cancer Reference Standards

December 20, 2023/in Partners, Synthetic Controls, Twist/by Harshita Sharma

Twist cfDNA Pan-Cancer Reference Standard v2

The Twist cfDNA Pan-Cancer Reference Standard v2 is a meticulously engineered tool tailored for genomics professionals developing and validating NGS-based liquid biopsy assays. This reference standard provides a reliable and reproducible resource for detecting clinically relevant variants, enabling researchers to confidently evaluate assay performance at every stage. By integrating a wild-type (WT) cell-free DNA (cfDNA) background with synthetic oligonucleotides carrying mutant alleles, the material delivers exceptional precision and sensitivity.

Researchers can leverage this standard to define critical analytical parameters, including the Limit of Detection (LoD) and Limit of Blank (LoB), ensuring robust assay calibration and quality control. Ideal for both early-stage assay development and ongoing process monitoring, the Twist cfDNA Pan-Cancer Reference Standard v2 empowers genomics teams to accelerate liquid biopsy innovation while maintaining rigorous accuracy and reproducibility.

But... Why These Panels?

Comprehensive Detection of Cancer Variants

458 unique naturally occurring cancer variants

132 clinically relevant variants

Covers 84 different genes involved in cancer

Better Design of Background
DNA

Background DNA derived from human cfDNA samples

DNA size profile and post-sequencing profile mimic native cfDNA

Designed for Precision and Flexibility

Seven individual VAF percentages to choose from

Digital Droplet PCR verification of VAF percentages

Convenient test set of all VAF percentages available

Download Product Sheet, Data Files & Detailed FAQs

Unlock instantly with few steps.

Data To Back This Up

Fragment Profile Comparison: Twist vs. Competitors

Twist cfDNA Pan-Cancer Reference Standard v2 closely mimics the fragment size distribution of native cfDNA, including distinct mononucleosomal and dinucleosomal peaks. When compared to competitor reference materials standardized for peak height, Twist’s standards provide a more biologically accurate representation of circulating cell-free DNA, supporting realistic assay development and reliable performance benchmarking.

Schematic of Synthetic Variant DNA Design

Twist’s synthetic variant DNA is engineered to tile across each genomic locus with extensive overlap, ensuring high coverage and diverse fragment representation. This design captures the variant in multiple positions relative to the DNA termini, providing realistic fragment diversity and enabling more accurate assay performance assessment.

Background Mutation Rate Comparison

Background mutation rate measures the occurrence of non-germline variants in duplex consensus reads from target-enriched wild-type samples. Analysis across Twist cfDNA Pan-Cancer Reference Standard v2, native cfDNA, competitors, and Twist v1 shows that v2 closely matches the low background error rate of native cfDNA. Its superior fidelity—lower than both v1 and competitor standards—is achieved through a high-precision production process, ensuring more reliable and accurate assay benchmarking.

INDEL Size Distribution

The Twist cfDNA Pan-Cancer Reference Standard v2 includes a wide range of insertion and deletion (INDEL) sizes, from deletions of 30 bp to insertions of 15 bp. Visualized as a histogram (bin width = 1), this distribution allows researchers to comprehensively evaluate INDEL detection performance across diverse fragment lengths. Single nucleotide variants (SNVs) are not included in this visualization, highlighting the standard’s focus on structural variant representation and assay sensitivity testing.

Variant Calling in Target Enrichment Workflows

Twist cfDNA Pan-Cancer Reference Standards deliver highly accurate variant detection across a range of variant allele frequencies (VAFs). Using a custom panel targeting 215 SNVs and sequencing to 80,000× raw coverage before UMI deduplication, the observed mean VAFs closely match the intended levels. This precision allows researchers to confidently benchmark and validate their NGS-based assays, ensuring reliable performance across the full spectrum of variant frequencies.

Custom Panels

December 20, 2023/in NGS, Partners, Twist/by Harshita Sharma

PRODUCTS

NGS Custom Panels

Twist Custom NGS Target Enrichment Panels - Precision Panels, Distributed by Decode Science

Twist Bioscience’s custom target enrichment panels are designed using a silicon-based DNA synthesis platform that produces highly accurate, reliable probes for next-generation sequencing (NGS). These panels can be tailored to suit a wide variety of applications, from small and highly focused panels targeting specific regions to large and complex designs that span broad genomic areas, making them suitable for almost any sequencing project. The combination of advanced design algorithms, proprietary synthesis processes, and a streamlined production pipeline ensures that each panel delivers uniform coverage, reduced off-target effects, and consistent, high-quality performance across sequencing platforms.

Another advantage of Twist’s approach is the flexibility it provides. Researchers can expand existing panels, update or enhance them with new content, or even combine multiple designs into blended panels to support evolving project needs. Turnaround times are fast, and the resulting panels are built to maintain accuracy and reproducibility, ensuring dependable results even in demanding research environments.

Exceptional, Reliable Performance

Twist’s double-stranded DNA probes undergo NGS-based quality control to ensure balanced representation and minimise dropout

Panel Blending

Easily combine two or more panels into a single design, either in your own lab or through Twist’s streamlined blending service.

Simple Design

Submit specifications online and benefit from Twist’s advanced design algorithms that optimize every panel for accuracy and efficiency.

Scalable Panels

From 100 probes to one million, Twist custom panels can be tailored to projects of any size while maintaining consistency and precision.

As the official distributor for Twist Bioscience in Australia and New Zealand, Decode Science makes accessing these panels straightforward. Our role is to connect your lab with Twist’s advanced technologies, ensuring you get the right custom panel solution for your sequencing projects—delivered locally with support when you need it.

Nucleic Acid Panel Designs

DNA

Twist Bioscience’s custom DNA target enrichment panels provide advanced solutions for a variety of sequencing applications. Using proprietary strategies such as probe shifter technology, these panels deliver precise, consistent coverage and high-performance results tailored to specific biological targets.

RNA

Twist Bioscience’s RNA custom target enrichment panels are designed to capture and enrich cDNA libraries for next-generation sequencing (NGS). Using innovative strategies such as exon-aware probe placement, these panels provide precise, high-performance coverage to maximize transcriptional insights from your RNA sequencing experiments.

Methylation

Twist Bioscience’s methylation target enrichment panels are designed to capture libraries prepared to reveal DNA methylation patterns. Using a unique design approach with four probe species per target—fully methylated and unmethylated, sense and antisense—these panels deliver uniform coverage while preserving accurate methylation signatures for reliable NGS analysis.

Featured Resources

FAQs

What is the standard probe length in a custom panel?

Custom panels typically use probes that are 120 base pairs (bp) long. Twist also offers alternative lengths—such as 80 bp or 100 bp—depending on your experimental needs, but all probes within a single panel are uniform in length.

Can target enrichment panels be customized for gene fusions and SNPs?

Yes. Twist custom panels can be designed for a variety of targets, including gene fusions, single nucleotide polymorphisms (SNPs), viruses, microsatellite instabilities (MSIs), structural variants, copy number variants (CNVs), and insertion/deletion events (InDels).

Can Twist design panels for targeted methylation (bisulfite) sequencing?

Yes. Twist offers custom panels specifically for targeted methylation sequencing, optimized to capture methylation patterns with high accuracy.

Are Twist target enrichment probes double-stranded?

Yes, all Twist target enrichment probes are double-stranded DNA, ensuring stable hybridization and reliable performance.

How is the quality of Twist probes ensured?

Twist performs NGS-based quality control by sequencing the probes to verify their representation within the pool, ensuring consistent and uniform performance across the panel.

Ready To Order?

As the official distributor for Twist Bioscience in Australia and New Zealand, Decode Science makes accessing these panels straightforward. Our role is to connect your lab with Twist’s advanced technologies, ensuring you get the right custom panel solution for your sequencing projects—delivered locally with support when you need it.

NGS Portfolio

Custom Panels

Viral Panels

Methylation Detection

Methylation

December 20, 2023/in NGS, Partners, Twist/by Harshita Sharma

PRODUCTS

NGS Methylation Detection

NGS Methylation Detection System

The Twist NGS Methylation Detection System provides a robust, end-to-end sample preparation solution for identifying methylated regions in the human genome. The workflow employs a unique enzymatic process from New England Biolabs® that is much less damaging to DNA, alongside Twist‘s Custom Methylation Panel design.

Whether you are investigating cellular differentiation or screening liquid biopsies for cancer, the system offers the most efficient methylation detection available.

NEBNext® EM-seq™ Kit for Twist Targeted Methylation Sequencing

In partnership with New England Biolabs (NEB), Twist Bioscience offers a new methylation sequencing workflow that improves the quality of libraries and removes the need for damaging bisulfite treatment during prep.

The workflow features enzymatic conversion of unmethylated cytosines (see figure) to identify sites of methyl-cytosine (5mC) and hydroxymethyl-cytosine (5hmC).

Enzymatic conversion produces more intact libraries with better representation, and ultimately achieves more sensitive methylation detection. The library preparation system is suitable for whole genome sequencing and downstream enrichment with Twist Methylation Panels.

EM-seq conversion involves a series of enzymatic steps to convert unmethylated cytosines into uracils. The final result is the same as conventional bisulfite conversion, making EM-seq compatible with existing analysis pipelines that use Bismark and bwa-meth.

Twist Human Methylome Panel

The Twist Human Methylome Panel targets 3.98M CpG sites through 123 Mb of genomic content to target biologically relevant methylation markers. Expansive content makes this panel an ideal choice for investigators to explore the methylation fraction in a diverse range of applications from cancer metastasis, human development, and functional genomics.

The panel is optimized and validated for use with the Twist methylation detection system for a complete end-to-end workflow with industry leading performance. High capture efficiency increases the sensitivity of detection across the footprint of the epigenome while decreasing sequencing costs. The panel is ideal for screening cohort samples and differentially methylated region discovery.

Enhanced Coverage, Advantages, and High Performance: A Comparative Analysis with Microarrays

The Twist Human Methylome Panel offers comprehensive coverage of the genome, targeting 3.98 million CpG sites within 123 Mb of genomic content. It efficiently identifies 84% of CpG islands and covers an additional 105,288,339 bases of related regions. In comparison to average microarrays, the panel overcomes static content limitations and enhances coverage across the epigenome. Microarrays suffer from constraints in methylation detection at extreme ends due to background noise and saturation, whereas the Methylome Panel, utilizing hybrid-capture panels and Next-Generation Sequencing (NGS), provides expanded content, single-base resolution, and a higher dynamic range for more accurate detection of differentially methylated regions. The panel’s performance is notable, achieving 90% coverage at 30x depth, 95% on-target rates, and high uniformity with a fold 80 of 1.54. Its efficient capture metrics instill confidence in accurate methylation fraction detection while minimizing sequencing costs.

Ready To Order?

Our team can help you in placing the order. Click below to get a quote and fast ordering.

NGS Portfolio

Custom Panels

Viral Panels

Methylation Detection

Have a question?

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

Or give us a call at:

1300 581 991

Protein Cartridges

Have a question?

DNA Cartridges

Have a question?

Qsep400

4-channel Bio-Fragment Analyzer designed for medium and large-sized labs, offering higher throughput and faster analysis.

Qsep400 features an integrated PC and touchscreen for user-friendly operation.

Capable of analyzing DNA, RNA, or protein with a 4~96 sample capacity.

Quantitative method provides comprehensive fragment size and concentration data in a single run.

Have a question?

Qsep1-Plus

Smallest/portable-sized capillary electrophoresis Bio-Fragment Analyzer for DNA, RNA, and protein.

Qsep1-Plus is ideal for small laboratories with low throughput (1~15 samples) needs.

The system supports Wi-Fi and cable connections, breaking the barriers of space.

10+ types of cartridges can be easily exchanged between various applications.

The provided quantitative method delivers fragment size and concentration information in one run.

Have a question?

Qsep100

Standard-sized capillary electrophoresis Bio-Fragment Analyzer for DNA, RNA, and protein.

Ideal for small to medium-sized labs with 1~96 sample capacity.

Easily exchangeable cartridges for versatile applications.

Provides quantitative data on fragment size and concentration in a single run.

Have a question?

Qsep1

Smallest/portable-sized capillary electrophoresis Bio-Fragment Analyzer for DNA, RNA, and protein.

Ideal for small laboratories with low throughput needs (1~8 samples).

Supports Wi-Fi and cable connections, enhancing spatial flexibility.

Easy exchange of 10+ cartridges between various applications.

Quantitative method provides fragment size and concentration info in a single run.

Have a question?

Synthetic Viral Controls

Have a question?

Comprehensive Detection of Cancer Variants

Better Design of Background DNA

Designed for Precision and Flexibility

Unlock instantly with few steps.

Chris Wicky

NGS Custom Panels

Exceptional, Reliable Performance

Panel Blending

Simple Design

Scalable Panels

Chris Wicky

NGS Methylation Detection

Have a question?

Instant Download

Instant Download

Instant Download

Instant Download

Special October Offer

FREE UMBRELLA

Better Design of Background
DNA