Entries by Harshita Sharma

Smash the limits of single cell sequencing with Parse

Smash the limits of single cell sequencing.

Join us to learn about Parse’s single cell whole transcriptome technology and recently
launched Evercode V3 Kits. More cells, more samples, more clarity.

Combinatorial barcoding technology strips away the limitations and frustrations of yesterday’s single cell approach. It ditches the specialized instrument, freeing you to pursue unprecedented discoveries. Unleash the potential of single cell. Decode Science and Parse Biosciences invite you to a seminar discussing the advances in fixation-based single cell transcriptomics including our V3 chemistry, TCR/BCR kits, CRISPR Detect and Gene Capture.

 

MEET THE SPEAKER

John received his PhD at Duke University, where he studied cis-regulatory element activation during limb regeneration. He then spent a few years as a postdoc at the University of California, Merced where he studied early organ formation using single-cell genetic and epigenetic approaches. As a Field Application Scientist at Parse Biosciences, John assists scientists with their single-cell genomics experiments, from experimental design, sample preparation, single-cell library workflows, data analysis, and more.

John’s favorite model organism are zebrafish, both embryos and adults. In his free time John enjoys eating spicy food, and dabbles in growing his own hot chili pepper plants.

Auckland

SEMINAR 1

Date: 8th May 2024

Time: 10am – 11am

Location: University of Auckland FMHS Room 503-126

SEMINAR 2

Date: 8th May 2024

Time: 1:30pm – 2.30pm 

Location: University of Auckland Old Government House, VC Suite


Dunedin

Date: 6th May 2024

Seminar 1: 10:30 AM : University of Otago Room 3.27 Dept of Biochemistry

Seminar 2: 12 PM: University of Otago Barnett Lecture Theatre


Wellington

Date: 7th May 2024

Seminar 1: 10:30 AM : Seminar Room, Malaghan Institute


Brisbane

Date: 10th May 2024

Seminar 1: 10-11AM – Queensland Institute of Medical Research
Seminar 2: 2PM – 3PM – Translational Research Institute Room 2003


Sydney

SEMINAR 1

Date: 13th May 2024

Time: 10 – 11am

Location: Mackenzie Room, Charles Perkins Centre, University of Sydney.

SEMINAR 2

Date: 13th May 2024

Time: 1 – 2pm

Location: Level 5 Conference Room, Victor Chang Cardiac Research Institute.


Melbourne

Date: 14th May 2024

Seminar: 3:00 PM – 4:00 PM – WEHI Davis Auditorium, Melbourne


Canberra

Date: 15th May 2024

Time: 12:30 PM – 1:30 PM

Location: Australian National University, John Curtin School of Medical Research, Finkel Theatre


Perth

SEMINAR 1

Date: 17th May 2024

Time: 10-11AM

Location: Harry Perkins Research Institute in the McCusker Auditorium

SEMINAR 2

Date: 17th May 2024

Time: 2PM – 3PM

Location: 360.3.030, Boola Katitjin in Murdoch University

Evercode TCR Mega

PRODUCTS

Evercode TCR Mega

1M CELLS

96 SAMPLES

Unlock scalable immune profiling capabilities with Evercode™ TCR Mega, empowering you to analyze up to 1 million cells at a time. In the intricate landscape of immunity, comprehensive data is key. With Evercode™ TCR Mega, you can achieve unparalleled resolution in studying TCR clonotype diversity and T-cell states.

Benefit from the expansive scale of Evercode™ TCR Mega, which offers a host of advantages alongside the wealth of information provided by WT profiles. Whether you’re exploring immune responses, investigating cellular dynamics, or delving into immunotherapy research, Evercode™ TCR Mega equips you with the tools to navigate the complexities of the immune system with confidence and precision.

EXPONENTIALLY
SCALABLE

Evercode's combinatorial barcoding
enables you to dramatically
scale up the cells and samples per experiment.

NO INSTRUMENT
REQUIRED

If you have a centrifuge,
thermal cycler,
and some pipettes,
you’re ready to go.

UNMATCHED DATA QUALITY

Better detect lowly expressed
genes and avoid ambient RNA common
in droplet-based
single cell sequencing.

WORKS WITH FIXED CELLS AND NUCLEI

Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

Up to 1 million cells in a single experiment

Experience the power of scale with Evercode. Conduct experiments with up to 1 million cells in a single run, unlocking the immense diversity within the immune repertoire like never before. With Evercode, identify an extensive array of TCR clonotypes, providing unparalleled insights into immune function and response.

Not only can Evercode detect clonotypes, but it also offers the capability to map them to T cell subtype clusters. By analyzing gene expression profiles from nearly 1 million T cells isolated from PBMCs, Evercode enables the classification of cells into distinct T cell subtypes. This comprehensive approach ensures a deeper understanding of immune dynamics and facilitates more nuanced analysis of immune responses.

High TCR detection in activated and primary T cells

Experience outstanding TCR detection in both activated and primary T cells with our cutting-edge profiling techniques. In our investigation, T cells derived from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation through culture for 3 days with CD3/CD28 beads and IL-2 (Activated).

Our results demonstrate robust TCR detection in both experimental conditions, highlighting the versatility and reliability of our methodology across diverse T cell states. Whether profiling primary T cells or their activated counterparts, our approach ensures accurate and comprehensive characterization of the TCR repertoire, providing invaluable insights into immune responses and cellular dynamics.

Trust in our advanced profiling techniques to deliver precise and high-fidelity data, enabling a deeper understanding of T cell biology and immunological processes. With our innovative methodologies, delve into the complexities of the immune system with confidence and clarity, paving the way for transformative discoveries in immunology.

Comprehensive immune repertoire detection

Immerse yourself in unparalleled detection of the immune repertoire with the Evercode™ TCR kit, meticulously crafted to offer the most comprehensive profile attainable. In a groundbreaking study spanning 8 donors, our kit revealed the identification of nearly 500,000 unique beta chain clonotypes.

Notably, the majority of these clonotypes were deemed rare, emphasizing the remarkable sensitivity and depth of our detection capabilities. With the Evercode™ TCR kit at your disposal, you gain the ability to unveil the complete spectrum of immune diversity, from commonplace to exceptionally rare clonotypes. This empowers you to delve into the intricacies of immune responses with unparalleled precision and breadth, opening new avenues for exploration and discovery in immunology.

tcr parse workflow

Ready to Order?

Our team can help you in placing the order. Click below to get a quote and fast ordering.

Let’s Find You an Application That Helps
Your Research

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







    Or give us a call at:

    1300 581 991

    Evercode TCR

    PRODUCTS

    Evercode TCR

    10K CELLS

    12 SAMPLES

    Explore the depths of the immune repertoire with our cutting-edge solution: single-cell TCR profiling combined with whole transcriptome analysis—no additional instrumentation required.

    With our state-of-the-art technology, you can detect TCRs with remarkable sensitivity while simultaneously capturing transcriptome-wide gene expression, including essential T-cell subtype markers. Delve into the intricate cellular landscape and unlock unprecedented insights by examining paired alpha and beta sequences within individual cells.

    This revolutionary approach empowers you to unravel the complex interplay between TCR diversity and gene expression profiles at the single-cell level, providing a holistic understanding of immune responses and cellular heterogeneity. Bid farewell to the constraints of conventional methods and embark on a transformative journey in immunogenomics research with our integrated solution.

    EXPONENTIALLY
    SCALABLE

    Evercode's combinatorial barcoding
    enables you to dramatically
    scale up the cells and samples per experiment.

    NO INSTRUMENT
    REQUIRED

    If you have a centrifuge,
    thermal cycler,
    and some pipettes,
    you’re ready to go.

    UNMATCHED DATA QUALITY

    Better detect lowly expressed
    genes and avoid ambient RNA common
    in droplet-based
    single cell sequencing.

    WORKS WITH FIXED CELLS AND NUCLEI

    Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

    High TCR detection in activated and primary T cells

    Witness exceptional TCR detection in both activated and primary T cells through our state-of-the-art profiling techniques. In our investigation, T cells sourced from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation via culture for 3 days with CD3/CD28 beads and IL-2 (Activated).

    Our findings reveal robust TCR detection in both experimental conditions, underscoring the versatility and dependability of our methodology across various T cell states. Whether profiling primary T cells or their activated counterparts, our approach guarantees precise and comprehensive characterization of the TCR repertoire, offering invaluable insights into immune responses and cellular dynamics.

    Rely on our advanced profiling techniques to deliver meticulous and high-fidelity data, facilitating a deeper comprehension of T cell biology and immunological processes. With our innovative methodologies, explore the intricacies of the immune system with confidence and clarity.

    Comprehensive immune repertoire detection

    Experience unparalleled detection of the immune repertoire with the Evercode™ TCR kit, designed to provide the most comprehensive profile available. In a groundbreaking study encompassing 8 donors, our kit identified nearly 500,000 unique beta chain clonotypes.

    Remarkably, the vast majority of these clonotypes were classified as rare, highlighting the sensitivity and depth of our detection capabilities. With the Evercode™ TCR kit, you can uncover the full spectrum of immune diversity, from common to exceedingly rare clonotypes, empowering you to explore the intricacies of immune responses with unprecedented precision and breadth.

    tcr parse workflow

    Ready to Order?

    Our team can help you in placing the order. Click below to get a quote and fast ordering.

    Let’s Find You an Application That Helps
    Your Research

    Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







      Or give us a call at:

      1300 581 991

      Evercode TCR Mini

      PRODUCTS

      Evercode TCR Mini

      100K CELLS

      48 SAMPLES

      Unlock the complexity of the immune repertoire with our innovative solution: single-cell TCR profiling combined with whole transcriptome analysis—all without the need for additional instrumentation.

      With our advanced technology, you can achieve sensitive detection of TCRs while simultaneously measuring transcriptome-wide gene expression, including crucial T-cell subtype markers. Dive deep into the cellular landscape and gain unparalleled insights by analyzing paired alpha and beta sequences within the same cell.

      This groundbreaking approach empowers you to uncover the intricate interplay between TCR diversity and gene expression profiles at the single-cell level, providing a comprehensive understanding of immune responses and cellular heterogeneity. Say goodbye to the limitations of traditional methods and embark on a new era of immunogenomics research with our integrated solution.

      EXPONENTIALLY
      SCALABLE

      Evercode's combinatorial barcoding
      enables you to dramatically
      scale up the cells and samples per experiment.

      NO INSTRUMENT
      REQUIRED

      If you have a centrifuge,
      thermal cycler,
      and some pipettes,
      you’re ready to go.

      UNMATCHED DATA QUALITY

      Better detect lowly expressed
      genes and avoid ambient RNA common
      in droplet-based
      single cell sequencing.

      WORKS WITH FIXED CELLS AND NUCLEI

      Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

      High TCR detection in activated and primary T cells

      Experience high TCR detection in both activated and primary T cells with our advanced profiling techniques. In our study, T cells isolated from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation through culture for 3 days with CD3/CD28 beads and IL-2 (Activated).

      Our results demonstrate robust TCR detection in both scenarios, showcasing the versatility and reliability of our methodology across different T cell states. Whether profiling primary T cells or activated counterparts, our approach ensures accurate and comprehensive characterization of the TCR repertoire, providing invaluable insights into immune responses and cellular dynamics.

      Count on our advanced profiling techniques to deliver precise and high-quality data, enabling deeper understanding of T cell biology and immunological processes.

      tcr parse workflow

      Ready to Order?

      Our team can help you in placing the order. Click below to get a quote and fast ordering.

      Let’s Find You an Application That Helps
      Your Research

      Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







        Or give us a call at:

        1300 581 991

        Evercode WT Mega

        PRODUCTS

        Evercode WT Mega

        1M CELLS

        96 SAMPLES

        Streamline the scaling of your single-cell projects with Evercode™ split-pool combinatorial barcoding. This innovative technique offers a straightforward, instrument-free solution to single-cell sequencing, revolutionizing the process with its simplicity and versatility.

        With Evercode™, you can effortlessly adopt a highly sensitive approach to single-cell sequencing, regardless of your lab’s resources or expertise level. The simplicity of this method makes it accessible to researchers of all backgrounds, while still delivering unparalleled sensitivity, scalability, and flexibility.

        Say goodbye to complex instrumentation and cumbersome protocols. Evercode™ empowers labs of any size to embark on single-cell sequencing projects with confidence, paving the way for groundbreaking discoveries in cellular biology and beyond.

        EXPONENTIALLY
        SCALABLE

        Evercode's combinatorial barcoding
        enables you to dramatically
        scale up the cells and samples per experiment.

        NO INSTRUMENT
        REQUIRED

        If you have a centrifuge,
        thermal cycler,
        and some pipettes,
        you’re ready to go.

        UNMATCHED DATA QUALITY

        Better detect lowly expressed
        genes and avoid ambient RNA common
        in droplet-based
        single cell sequencing.

        WORKS WITH FIXED CELLS AND NUCLEI

        Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

        Experience a revolution in gene detection sensitivity with Evercode WT v2.

        In a rigorous comparative study conducted on mouse brain samples, Evercode WT v2 demonstrated exceptional superiority over the Chromium Next GEM Single Cell 3’ Kit v3.1. Impressively, Evercode WT v2 detected an average of 84% more genes at a common read depth target of 20,000 reads per cell.

        With Evercode WT v2 at your disposal, you gain the power to uncover a broader spectrum of genes and dive deeper into gene expression profiles. This invaluable wealth of information will enrich your research endeavors, providing nuanced insights into cellular dynamics and molecular processes. Elevate your single-cell transcriptomics studies to unprecedented heights with the unmatched sensitivity and precision offered by Evercode WT v2.

        Evercode™ delivers more results per experiment

        Evercode™ sets a new standard by delivering more results per experiment compared to leading droplet-based technologies. This means that with Evercode™, you can achieve your research goals with significantly fewer experiments, saving time, resources, and effort.

        By maximizing the efficiency of each experiment, Evercode™ allows you to generate more data and insights in less time. Whether you’re exploring gene expression profiles, investigating cellular heterogeneity, or uncovering novel biological pathways, Evercode™ streamlines the process and accelerates your research progress.

        With Evercode™, you can optimize your experimental workflow and achieve more impactful results with fewer resources expended. Experience the difference that Evercode™ can make in advancing your scientific discoveries and pushing the boundaries of single-cell analysis.

        Fix now, run later

        Our innovative technology allows you to fix cells or nuclei as soon as they’re available, effectively preserving the biological integrity until you’re ready to proceed with your experiments. With just a 30-minute fixation process, your samples remain stable for up to 6 months.

        This approach offers unparalleled flexibility in your research workflow. Whether you’re conducting a timecourse study, collaborating across multiple laboratories, or need to segregate sample preparation from core lab space, fixation provides the freedom to work according to your schedule and preferences.

        With Evercode™, you can confidently lock in the biology of your samples, knowing that they’ll be ready for analysis whenever you are. Say goodbye to time constraints and logistical challenges – embrace the flexibility of fixation with Evercode™.

        Ready to Order?

        Our team can help you in placing the order. Click below to get a quote and fast ordering.

        Let’s Find You an Application That Helps
        Your Research

        Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







          Or give us a call at:

          1300 581 991

          Evercode WT

          PRODUCTS

          Evercode WT

          100K CELLS

          48 SAMPLES

          Realize your single-cell aspirations with Evercode™ split-pool combinatorial barcoding. This straightforward, instrument-free solution revolutionizes single-cell sequencing, offering unparalleled sensitivity, scalability, and flexibility to labs of any size.

          With Evercode™, you can effortlessly adopt a highly sensitive approach to single-cell sequencing, empowering you to unlock the complexities of cellular heterogeneity with ease. Scale your experiments to new heights while maintaining precision and reliability, thanks to Evercode’s adaptable design and seamless workflow.

          Say goodbye to cumbersome instrumentation and complex protocols – Evercode™ simplifies single-cell sequencing, making it accessible to researchers at all levels. Whether you’re exploring the intricacies of developmental biology, investigating immune responses, or unraveling the mysteries of cancer heterogeneity, Evercode™ equips you with the tools you need to achieve your single-cell ambitions.

          EXPONENTIALLY
          SCALABLE

          Evercode's combinatorial barcoding
          enables you to dramatically
          scale up the cells and samples per experiment.

          NO INSTRUMENT
          REQUIRED

          If you have a centrifuge,
          thermal cycler,
          and some pipettes,
          you’re ready to go.

          UNMATCHED DATA QUALITY

          Better detect lowly expressed
          genes and avoid ambient RNA common
          in droplet-based
          single cell sequencing.

          WORKS WITH FIXED CELLS AND NUCLEI

          Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

          Higher Sensitivity with Evercode WT v2

          Embark on a journey of unparalleled sensitivity in gene detection with Evercode WT v2. In a comprehensive comparative study conducted on mouse brain samples, Evercode WT v2 demonstrated remarkable superiority over the Chromium Next GEM Single Cell 3’ Kit v3.1. Remarkably, Evercode WT v2 detected an average of 84% more genes at a common read depth target of 20,000 reads per cell.

          With Evercode WT v2 as your tool of choice, you can uncover a broader spectrum of genes and delve deeper into gene expression profiles. This invaluable information will enrich your research endeavors, providing nuanced insights into cellular dynamics and molecular processes. Elevate your single-cell transcriptomics studies to unprecedented heights with the unmatched sensitivity and precision offered by Evercode WT v2.

          Boost the signal, reduce the noise

          Elevate signal quality and minimize noise in your single-cell RNA sequencing (scRNA-seq) experiments with Evercode™. Multiplets, a common challenge in scRNA-seq approaches, can complicate data analysis and obscure biological insights. By adopting Evercode™, which utilizes a cell-as-reaction-vessel approach, you can eliminate issues associated with multiplets, leading to cleaner and more accurate data.

          In a human-mouse species mixing experiment conducted with Evercode™, we achieved an exceptionally low multiplet rate of only 2.3%. This rate significantly outperforms traditional droplet-based approaches, demonstrating Evercode’s™ effectiveness in reducing multiplet interference and enhancing data quality.

          With Evercode™, you can confidently boost signal detection while minimizing noise, enabling more precise and insightful analysis of single-cell transcriptomic data. Say goodbye to multiplet-related challenges and unlock the full potential of your scRNA-seq experiments with Evercode™.

          Ready to Order?

          Our team can help you in placing the order. Click below to get a quote and fast ordering.

          Let’s Find You an Application That Helps
          Your Research

          Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







            Or give us a call at:

            1300 581 991

            Evercode WT Mini

            PRODUCTS

            Evercode WT Mini

            10K CELLS

            12 SAMPLES

            Introducing Evercode™ WT Mini V2, the revolutionary solution for single-cell whole transcriptome analysis. Designed to operate without the need for additional instruments, the Evercode™ WT Mini V2 allows you to delve into single-cell transcriptomics with ease and convenience.

            Key features include:

            1. Compact Design: The Evercode™ WT Mini V2 is perfectly sized for researchers looking to explore single-cell transcriptomics on a smaller scale. Its compact design makes it ideal for generating proof-of-concept results before scaling up to larger platforms.

            2. Quality Results: Experience the exceptional quality of results achievable with Parse technology. The Evercode™ WT Mini V2 enables you to obtain reliable and accurate transcriptomic data from individual cells, providing valuable insights into your biological samples.

            3. Scalability: As your research progresses, seamlessly transition to larger platforms such as the Evercode™ WT or Evercode™ WT Mega to delve deeper into your biology. The Evercode™ WT Mini V2 serves as an ideal starting point for expanding your single-cell transcriptomics studies.

            With Evercode™ WT Mini V2, unlock the potential of single-cell transcriptomics and embark on a journey of discovery in your research. Explore the complexities of gene expression at the single-cell level and uncover new insights into cellular heterogeneity and biological processes.

            EXPONENTIALLY
            SCALABLE

            Evercode's combinatorial barcoding
            enables you to dramatically
            scale up the cells and samples per experiment.

            NO INSTRUMENT
            REQUIRED

            If you have a centrifuge,
            thermal cycler,
            and some pipettes,
            you’re ready to go.

            UNMATCHED DATA QUALITY

            Better detect lowly expressed
            genes and avoid ambient RNA common
            in droplet-based
            single cell sequencing.

            WORKS WITH FIXED CELLS AND NUCLEI

            Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

            Higher Sensitivity with Evercode WT v2

            Experience unmatched sensitivity in gene detection with Evercode WT v2. In a comparative study conducted in mouse brain samples, Evercode WT v2 outperformed the Chromium Next GEM Single Cell 3’ Kit v3.1, detecting an average of 84% more genes at a common read depth target of 20,000 reads per cell.

            With Evercode WT v2, you can uncover a broader spectrum of genes and gain deeper insights into gene expression profiles, providing invaluable information for your research endeavors. Elevate your single-cell transcriptomics studies to new heights with the superior sensitivity of Evercode WT v2

            Lower multiplet rates than droplet-based approaches

            Achieve significantly lower multiplet rates compared to droplet-based approaches with Evercode WT. In a human-mouse species mixing experiment utilizing Evercode WT, we observed an impressively low multiplet rate of only 2.3%. This rate is substantially lower than what is typically encountered with droplet-based methods.

            By leveraging Evercode WT, researchers can confidently minimize the occurrence of multiplets, ensuring greater accuracy and reliability in single-cell transcriptomic analysis. This enhanced precision allows for more accurate interpretation of biological data and deeper insights into complex biological systems.

            Ready to Order?

            Our team can help you in placing the order. Click below to get a quote and fast ordering.

            Let’s Find You an Application That Helps
            Your Research

            Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







              Or give us a call at:

              1300 581 991

              OGM Data Services

              PRODUCTS

              OGM Data Services

              Compute Solutions Bionano

              USING OGM IN YOUR RESEARCH

              Incorporating Optical Genome Mapping (OGM) into your research opens up a realm of possibilities for detecting genome-wide structural variations with unparalleled sensitivity and unbiased analysis. Unlike sequencing-based technologies and conventional cytogenetic techniques, OGM offers a comprehensive and highly sensitive approach to uncovering structural variations within the genome.

              By leveraging our services laboratory, you can embark on projects to analyze samples using OGM. Our expert team will guide you through the process, ensuring accurate and reliable results. Whether you’re exploring genetic anomalies in cancer, investigating constitutional genetic disorders, or studying complex genomic rearrangements, OGM provides a powerful tool for uncovering structural variations with precision and efficiency.

              With OGM, you can gain deeper insights into the genomic landscape of your samples, leading to breakthroughs in understanding disease mechanisms, identifying potential therapeutic targets, and advancing personalized medicine initiatives. Join us in harnessing the transformative potential of OGM to drive forward your research and uncover the hidden secrets of the genome.

              HOW IT WORKS

              During an Optical Genome Mapping (OGM) research project with our services laboratory, you’ll embark on a collaborative journey with our experienced team.

               

              Here’s how it works:

              1. Project Initiation: You’ll collaborate with our team to define the scope of your research project. Together, we’ll discuss your research question, objectives, and sample set selection.
              2. Sample Analysis: Once the project scope is defined, our laboratory will perform OGM and initial structural variant analysis on your selected sample set. Using state-of-the-art technology and methodologies, we’ll generate high-quality data to address your research needs.
              3. Collaboration and Communication: Throughout the project, we’ll maintain open communication channels to ensure that your research goals are met. We’ll provide regular updates on the progress of the analysis and seek your input as needed.
              4. Data Delivery: At the conclusion of the project, you’ll receive comprehensive deliverables, including raw molecules data, assemblies, and annotated structural variant (SV) calls. Additionally, we’ll provide training on our proprietary visualization software, empowering you to explore and interpret the results effectively.
              5. Data Integration: Our team will support you in integrating OGM results with other data types, such as sequencing and array data. We’ll facilitate exports to various file formats, including VCF files, enabling seamless comparison and combination of OGM results with other datasets.

              Through this collaborative approach, we aim to deliver actionable insights that advance your research objectives and drive scientific discovery. Join us in unlocking the full potential of OGM to uncover the mysteries of the genome and accelerate breakthroughs in your field of study.

              COMPARISON ANALYSIS

              Structural variants called against GRCh37/hg19 or GRCh38/hg38 will be filtered against a control database or gene list of choice based on the project goals. Dual or trio variant annotation can be run for various applications. These include identifying de novo or inherited variants in germline samples, somatic variants in matched tumor-control samples, and targeted structural variants in edited versus unedited control cell lines. Just indicate the relationship between samples in the intake form.

              Ready to Order?

              Our team can help you in placing the order. Click below to get a quote and fast ordering.

              Bionano Portfolio

              Let’s Find You an Application That Helps
              Your Research

              Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







                Or give us a call at:

                1300 581 991

                Compute Solutions

                PRODUCTS

                Compute Solutions

                Compute Solutions Bionano

                Experience comprehensive solutions for Optical Genome Mapping (OGM) data management and processing with Bionano Compute. Our suite encompasses a full spectrum of hardware, software, and cloud-based solutions, ensuring a seamless workflow from start to finish.

                Bionano Compute offers end-to-end experiment management and bioinformatics processing, empowering researchers with robust tools for efficient data analysis. Additionally, it provides convenient management and monitoring tools tailored for the Saphyr™ and Stratys™ instruments, streamlining operations and enhancing productivity.

                With Bionano Compute, researchers can harness the power of advanced technology to unlock insights from genomic data with unparalleled ease and efficiency.

                The Stratys™ Compute high-performance workstation ensures seamless scalability for your workflow demands.

                Fueled by NVIDIA RTX GPUs, it offers expedited runtimes and reduced compute costs, thanks to its cutting-edge technology. With each software release, expect accelerated performance, enhancing overall efficiency.

                Experience unparalleled sensitivity in detecting all classes of structural variants (SVs) across the genome with the latest informatics pipeline tailored for Optical Genome Mapping (OGM) data.

                Installed alongside the Stratys instrument, the Stratys Compute workstation minimizes IT burdens and implementation time, optimizing your setup for streamlined operations.

                Reduce infrastructure costs and expand your Optical Genome Mapping (OGM) capacity effortlessly with Bionano Compute On Demand.

                This pay-per-use solution, accessible via the Bionano Access web server for Bionano Solve operations, revolutionizes OGM data analysis from the Saphyr™ or Stratys™ instruments without necessitating additional infrastructure. Enjoy the flexibility and scalability your experiments demand with Compute On Demand.

                Key advantages of Compute On Demand include:

                1. Analyze large genomes and numerous samples simultaneously, maximizing throughput and efficiency.
                2. Perform pipeline analysis operations seamlessly, without concerns about server capacity constraints.
                3. Safeguard data integrity with encryption measures, ensuring secure operations and compliance with data protection regulations.
                4. Maintain data center compliance with IPAA, CSA, SOC2, and ITAR regulations, guaranteeing adherence to industry standards and regulations.

                With Bionano Compute On Demand, unlock the full potential of your OGM experiments while optimizing costs and maintaining data security and compliance.

                Experience high-speed, on-site Optical Genome Mapping (OGM) data processing tailored for the Saphyr™ with the Saphyr™ Compute Server.

                This compact solution delivers cluster-like performance at an affordable cost, revolutionizing your data analysis capabilities.

                Key features of the Saphyr™ Compute Server include:

                1. Cluster-like Performance: Enjoy the power of multiple simultaneous analyses and sustained throughput, reducing downtime and accelerating your research.

                2. Rapid Analysis: Perform rare variant analysis and annotation of a human genome in approximately nine hours, enabling swift insights into complex genomic structures.

                3. User-Friendly Interface: Seamlessly integrate the Saphyr™ Compute Server into any network setup with its simple web-based interface, ensuring compatibility and ease of use.

                With the Saphyr™ Compute Server, spend less time waiting for data and more time delving into meaningful results, advancing your research endeavors with unparalleled efficiency and speed.

                Ready to Order?

                Our team can help you in placing the order. Click below to get a quote and fast ordering.

                Bionano Portfolio

                Let’s Find You an Application That Helps
                Your Research

                Get a call from your local Decode Science representative to help you find the best fit genomics products for you.







                  Or give us a call at:

                  1300 581 991

                  Sample Preparation Kits

                  PRODUCTS

                  Sample Preparation Kits

                  Sample Prep Kits Bionano

                  Effortlessly prepare samples for Optical Genome Mapping (OGM) with Bionano’s comprehensive Sample Preparation Solutions, ensuring accurate identification of structural variants.

                  OGM necessitates labeled ultra-high molecular weight (UHMW) DNA, and Bionano offers a diverse range of DNA sample prep kits designed for simple and reliable isolation of UHMW DNA from various sample types. Once DNA isolation is complete, our Direct Label and Stain (DLS) kits can efficiently label DNA for compatibility with the Saphyr system.

                  With our Generation 2 Kits, featuring robust enhancements and optimizations to the sample preparation OGM workflow, you can achieve sample-to-answer results in just 3 to 4 days! Experience accelerated and streamlined sample preparation, paving the way for enhanced genomic analysis and structural variant detection.

                  Attain robust isolation and labeling of Ultra-High Molecular Weight (UHMW) DNA, crucial for visualizing large genomic structural variants.

                  Bionano’s innovative Solution Phase (SP) technology facilitates the isolation of DNA fragments exceeding 1 Megabase pair (Mbp) in length, consistently yielding average fragments surpassing 230 kilobase pairs (kbp).

                  To contextualize, while short-read sequencing generates reads up to 150 base pairs (bp) in length, even leading high-accuracy long-read sequencing methods offer read lengths limited to approximately 25 kilobases (kb). Bionano’s SP technology surpasses these limitations, enabling the analysis of genomic structural variants with unprecedented detail and accuracy.

                  Extract DNA from a diverse array of crucial sample types effortlessly with the latest Bionano SP DNA prep kits.

                  These kits excel at purifying Ultra-High Molecular Weight (UHMW) DNA from tissues, tumors, bone marrow aspirate (BMA), blood, cells, as well as various plant and animal tissues. This versatility makes Optical Genome Mapping (OGM) applicable across a wide spectrum of studies and applications, including oncology, constitutional genetic disease research, bioprocessing, and general scientific inquiry.

                  Bionano’s SP kits necessitate 1.5 * 10^6 cells (for blood, cell lines, and BMA) or 10 – 30 mg of tissue as input. Employing a lyse, bind, and wash process along with novel paramagnetic disks, these kits enable the isolation of UHMW DNA in approximately four hours. This streamlined workflow ensures efficient extraction of high-quality DNA, empowering researchers across various fields to unlock the mysteries of the genome with ease.

                  Boost your workflow throughput by integrating the efficiency of automation.

                  Through a pioneering collaboration with the Hamilton Company, Bionano presents the groundbreaking Long String Star V – the world’s inaugural automated platform tailored for the isolation of Ultra-High Molecular Weight (UHMW) DNA.

                  The Long String Star V stands as an assay-ready workstation, harmoniously designed to complement Bionano’s G2.LS DNA Isolation kits. With this innovative platform, a single operator can seamlessly extract UHMW DNA from up to 24 samples per day, revolutionizing sample processing efficiency while maintaining high-quality results. Experience unparalleled productivity and precision as you propel your research forward with the Long String Star V automation system.

                  The Hamilton Long String Star V

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