Knockout Immortalized Cells

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PRODUCTS

Knockout Immortalized Cells

Knock-in Immortalized Cell Lines

Reliable, Reproducible CRISPR Editing for Breakthrough Discoveries

Spend Less Time on Editing, More on Innovation: EditCo’s advanced automation eliminates time-consuming steps, allowing you to focus on impactful research.

Superior Performance & Scalability: Our CRISPR platform delivers high knockout efficiencies, ensuring consistent, reproducible results across experiments.

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EditCo Knockout Immortalized Cells

Characterize Genes Associated with Neurodegenerative Disease:

Develop immortalized cell line models to uncover and characterize genes involved in Parkinson’s Disease.

Investigate a Protein’s Mechanism of Action:

Accelerate your data generation with high-quality reagents that avoid high off-target issues to quickly and confidently confirm protein function.

Expedite Drug Discovery
Research:

Validate a new drug lead without having to invest time learning or optimizing CRISPR.

Thoroughly Confirm Your Phenotype in Multiple Models in Parallel:

Generate data in time for your next board meeting or publication by running assays in parallel to identify your targets.

XDel Knockout Cell Pools & Clones - EditCo | Decode Science
XDel Knockout Cell Pools & Clones

XDel is an advanced CRISPR knockout tool that eliminates uncertainty in gene editing. Using a groundbreaking guide RNA design approach, it provides highly effective, reliable, and repeatable gene knockouts, enabling researchers to speed up their breakthroughs with assurance.

  • – Higher Efficiency & Consistency: XDel technology ensures superior on-target knockout rates with minimal variability.
  • – Reduced Off-Target Effects: Achieve precise edits with lower unintended mutations compared to single-guide methods.
  • – Validated & Scalable: Persistent protein depletion enables direct use in functional assays, drug discovery, and disease modeling.
CRISPR Knockout Cell Pools & Clones
CRISPR Knockout Cell Pools & Clones

Accelerate your research with high-efficiency CRISPR Knockout Cell Pools & Clones from EditCo. Our cell pools provide a mix of edited and unedited cells for immediate assays, while clonal lines ensure precise gene knockouts with sequence-verified accuracy.

  • – 50%+ knockout efficiency in cell pools
  • – Up to 95% protein knockout for functional validation
  • – Single, double, or triple knockouts available
  • – Comprehensive QC & sequencing reports included
Knockout Cell Libraries – High-Throughput CRISPR Screening Made Easy

EditCo’s Knockout Cell Libraries enable high-efficiency CRISPR screening with over 90% editing success in a ready-to-use 96-well arrayed format. Designed for functional assays and drug target discovery, our libraries eliminate transfection challenges and infrastructure barriers.

  • – Multi-guide CRISPR design for precise knockouts
  • – High-throughput screening with scalable workflows
  • – Comprehensive QC & sequencing reports included
  • – Compatible with diverse assays for discovery & validation
Knockout Cell Libraries – High-Throughput CRISPR Screening Made Easy
Ready to Order?
Our team can help you in placing the order. Click below to get a quote and fast ordering.
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Immortalized Cells Portfolio

Knockout Immortalized Cells

Knock-in Immortalized Cells

Let’s Find You an Application That Helps Your Research

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

    Or give us a call at:

    1300 581 991

    Knock-in iPS Cells

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    PRODUCTS

    Knock-in iPS Cells

    iPSC_min

    Advanced CRISPR Knock-Ins for iPSC Research

    EditCo’s advanced CRISPR knock-ins empower neuroscience, cardiovascular, and regenerative medicine research by delivering precise edits in iPSCs while maintaining their quality, pluripotency, and integrity. Our high-throughput automated platform ensures fast lead times and high editing efficiencies, allowing you to focus on downstream applications like assay development and differentiation.

    With minimal off-target effects, our platform offers a range of knock-ins, including single nucleotide variants, tags, and small insertions (<100 bp), available in both homozygous and heterozygous states, as well as in clone or pool formats. Trust EditCo’s robust editing process to accelerate your discoveries with artifact-free, reliable CRISPR-edited iPSCs.

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    Knock-in Immortalized Cells

    Isogenic Neuronal Lines:

    Create isogenic neuronal lines by reverting disease SNV genotypes to wild type with CRISPR-edited iPSCs.

    Drug Screening:

    Enhance drug screening with gene-corrected control lines for disease-relevant cell types.

    Protein Tagging:

    Tag target proteins to study subcellular localization under endogenous regulation.

    Disease Modeling:

    Model mutations in disease-relevant cell types using high-quality edited iPSCs.

    iPS cells were assessed for standard pluripotency markers

    Image: iPS cells were assessed for standard pluripotency markers, three days post-editing.

    Single-guide RNA Knock-in Cell Pools

    Achieve high-efficiency CRISPR iPSC knock-ins with EditCo’s Knock-in iPS Cell Pools. These pools offer a mix of edited and unedited cells, giving you flexibility for clonal isolation. Our optimized platform ensures precise edits, while you have the option to perform clonal isolation yourself. For those looking for a fully automated process, explore our Knock-in iPS Cell Clones for homogeneity and convenience.

    Features:

    • – Cell Source: EditCo or customer supplied
    • – Available Edits: SNV, Tag, or Insertion
    • – CRISPR Design: Synthetic modified sgRNA, Donor ssODN
    • – Add-ons: QC for pluripotency testing

    Deliverables:

    • – Edited cell pools (2 vials with 5 million cells)
    • – Regular updates, sequencing data, and comprehensive QC reports

    EditCo ensures robust editing with high efficiency across a variety of iPSC lines, maintaining pluripotency and delivering consistent, reliable results.

    Single-guide RNA Knock-in Cell Clones

    EditCo’s Knock-in iPS Cell Clones provide homogeneous populations derived from single CRISPR-edited cells. Skip the editing and cloning process, and move directly into functional assays with high-quality, reliable clones. We manage the entire CRISPR editing and cloning process, ensuring you receive precise, genetically modified clones for accelerated research.

    Features:

    • – Cell Source: EditCo or customer supplied
    • – Genetic Modifications: SNV, Tag, or Insertion (Homozygous or Heterozygous)
    • – CRISPR Design: Synthetic modified sgRNA, Donor ssODN
    • – Add-ons: Additional clones, QC for pluripotency and karyotype testing

    Deliverables:

    • – 2 independent clones with the required knock-in (2 vials of 500,000 cells each)
    • – Regular progress updates, sequencing data, and comprehensive QC reports

    EditCo ensures precise SNV editing and delivers reliable, pluripotent clones ready for your downstream applications.

    SNV editing in iPS cell clones

    Image: 100% SNV editing in iPS cell clones.

    Use EditCo’s iPS Cell Lines or Bring Your Own
    EditCo provides iPS cell lines for all engineered cell orders at no extra cost. Alternatively, you can onboard your own cell lines.

    EditCo-supplied cell lines

    * Parental vials available for evaluation prior to booking an edit

    Ready to Order?
    Our team can help you in placing the order. Click below to get a quote and fast ordering.
    Get a Quote
    IPS Cells Portfolio

    Knockout iPS Cells

    Knock-in iPS Cells

    Let’s Find You an Application That Helps Your Research

    Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

      Or give us a call at:

      1300 581 991

      Knockout iPS Cells

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      PRODUCTS

      Knockout iPS Cells

      Knockout iPS Cells

      Precise and efficient models for cutting-edge disease research.

      EditCo’s cutting-edge CRISPR technology ensures accurate and efficient gene editing while maintaining iPSC quality, pluripotency, and overall cell integrity. Our automated platform, optimized guide design, and superior reagents enable high-efficiency knock-ins and knockouts, minimizing errors and off-target effects. With a focus on delivering reliable and functional gene modifications, our robust process allows researchers to confidently assay gene functions, model diseases, and explore new therapeutic targets.

      Whether you need precise knockouts or complex knock-ins, EditCo’s advanced editing solutions provide the accuracy and consistency required for high-impact scientific discoveries in biomedical research.

      Get a Quote
      Knock-in Immortalized Cells

      Gene Function Studies:

      Disrupt your target gene to assess its role in a phenotype or cellular function.

      Gene-Disease Linkage:

      Investigate genetic factors in neurodegenerative diseases using edited iPSCs and neuronal cell types.

      Pathway Analysis:

      Knock out genes in your disease pathway. Differentiate cells into disease-relevant types and test for drug targets.

      Target Validation:

      Validate targets in CRISPR-edited iPSCs to confirm gene-disease linkage in cell models.

      Single Guide Pools Results
      XDel Knockout Cell Pools and Clones

      XDel is a CRISPR technology for precise, efficient gene editing. With a unique guide RNA design, it ensures reproducible knockouts without affecting pluripotency or cell integrity, accelerating research in gene function, disease modeling, and drug development.

      • – High Efficiency: Superior editing and consistent knockouts.
      • – Reliable Results: Persistent protein depletion validated through assays.
      • – Reproducibility: Minimized variability for dependable outcomes.
      XDel Knockout Cell Pools & Clones - EditCo | Decode Science
      XDel multiple guide RNA off-target editing efficiency

      Features

      • – Cell Source: EditCo or customer supplied.
      • – Available Edits: Indel, fragment deletion, homozygous, or heterozygous.
      • – Design: Synthetic modified sgRNA.
      • – Add-Ons: Additional clones, testing.
      • – Deliverables: Updates, edited cell pools (2 vials), sequencing data, and QC reports.

      Superior Editing
      XDel offers more consistent and efficient on-target editing than single-guide RNA methods, ensuring reliable results.

      Reduced Off-Target Effects
      XDel delivers lower off-target editing compared to single-guide RNA, ensuring better precision.

      Robust Knockouts
      XDel pools maintain genomic stability, confirmed by karyotyping and PluriTest™.

      How XDel Works
      XDel uses up to 3 coordinated guides for reliable knockouts, offering more consistent edits than traditional single-guide methods.

      XDel pools and clones
      Multi-guide schematic-new
      Ready to Order?
      Our team can help you in placing the order. Click below to get a quote and fast ordering.
      Get a Quote
      IPS Cells Portfolio

      Knockout iPS Cells

      Knock-in iPS Cells

      Let’s Find You an Application That Helps Your Research

      Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

        Or give us a call at:

        1300 581 991

        Knock-in Immortalized Cells

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        PRODUCTS

        Knock-in Immortalized Cells

        Arrayed CRISPR sgRNA Libraries

        Get CRISPR-Engineered Cell Lines Faster and More Efficiently.

        EditCo’s Knock-in Immortalized Cells provide a fast and efficient way to integrate engineered cells into your research, using automated transfection optimization and RNP-based delivery to ensure high editing success with minimal off-target effects.

        By eliminating the delays and challenges of DIY CRISPR projects, our cost-effective solution enables you to model more genes and variants across multiple cell lines, accelerating your path to discovery without overspending.

        Get a Quote
        Knock-in Immortalized Cells

        Tag and Quantify Your Protein:

        Easily purify and measure your target protein with
        precise tagging.

        Create a Disease Model:

        Modify genes to introduce or correct mutations for studying disease phenotypes.

        Analyze Gene Regulation:

        Develop reporter cell lines with promoter tags to monitor
        gene activity.

        Uncover Protein Interactions:

        Use affinity tags to map protein-protein interactions and identify key partners.

        Single Guide Pools Results
        Cost-Effective CRISPR Knock-in Cell Pools – Flexible & Efficient

        EditCo’s Knock-in Immortalized Cell Pools provide a high-throughput, budget-friendly solution for introducing precise edits while maintaining a mixed population of edited and unedited cells.

        • – Optimized transfection for high-efficiency knock-ins
        • – Supports SNVs, tags, and large insertions with advanced HDR strategies
        • – Flexible clonal isolation—manage it yourself or opt for our Knock-in Clones
        • – Comprehensive QC & sequencing reports for reliable validation
        Precision-Verified CRISPR Knock-in Clones – Ready for Your Research

        EditCo’s Knock-in Immortalized Cell Clones provide a sequence-verified, clonal population for precise, high-quality knock-ins. Whether modifying SNVs, tagging proteins, or inserting large sequences, our automated isolation process ensures you receive a single-cell-derived clone with your desired edit.

        • – Guaranteed precision with fully validated knock-ins
        • – Endogenous tagging & SNV editing for functional studies
        • – Streamlined delivery with complete QC & sequencing reports
        • – Customizable options including additional clones & intermediate pools

        Skip the complexity—get ready-to-use, precision-edited clones with EditCo!

        Ready to Order?
        Our team can help you in placing the order. Click below to get a quote and fast ordering.
        Get a Quote
        Immortalized Cells Portfolio

        Knockout Immortalized Cells

        Knock-in Immortalized Cells

        Let’s Find You an Application That Helps Your Research

        Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

          Or give us a call at:

          1300 581 991