DNBSEQ T7+

MGI T7+ 2025
T7+: Ultra-Fast, High-Throughput Sequencing Without Compromise

T7+ is an integrated ultra-high-throughput sequencing platform built for labs that demand speed, accuracy, and scale. Leveraging MGI’s DNBSEQ™ Technology and SM2.0 biochemistry, it delivers over 14Tb of high-quality sequencing data in 24 hours, making large-scale genomics projects—from population studies to clinical pipelines—both feasible and efficient. Its 7-in-1 modular design automates the entire workflow, reducing hands-on time and minimizing potential errors.

Beyond sheer performance, T7+ is engineered with clinical relevance in mind. Its capacity for up to 35,000 whole-genome sequences annually ensures that your lab can meet high-throughput demands without compromising turnaround times. This efficiency directly translates to faster research insights, improved diagnostic workflows, and smoother integration into daily lab operations, helping you focus on what matters most: accurate, actionable genomic data.

>14 Tb/24h ultra-fast sequencing

7-in-1 automation: prep to analysis

QUAD-Flow Cells: PE150 & PE100 simultaneous

Q40 >90% high-quality output

Ergonomic & modular design

Smart system with diagnostics & self-healing

Omni-smart hub guides workflows

Checkpoint resume for uninterrupted runs

Learn more about how each feature works as you scroll.

Watch How T7+ Works
Why It Matters?

Every hour matters when precision, speed, and reliability determine outcomes. T7+ addresses these challenges by combining ultra-high throughput, rapid turnaround, and intelligent automation, so you can focus on results rather than processes.

Ultra-Fast Sequencing

Ultra-Fast Sequencing:

The proprietary TDI camera and high-density flow cells deliver over 14 Tb of high-quality data in 24 hours, supporting up to 35,000 whole-genome sequences per year. Large-scale projects can now be completed without bottlenecks.

Seamless Automation

Seamless Automation:

The 7-in-1 workflow integrates DNB preparation, loading, sequencing, waste management, data analysis, and compression. This reduces hands-on time, minimizes errors, and produces ready-to-analyze FASTQ files with Q40 >90%.

Chris Wicky

Clinical Genomics Manager - ANZ & Country Manager - NZ

Get a complete overview of T7+ performance, throughput, workflow automation, and configuration options. For guidance on integrating T7+ into your operations, Decode Science can provide personalized support and local assistance.
Omni Start Hub

Smart & Intuitive Operation:

Minimalist design, adjustable screen angles, and the Omni-smart hub guide operations with ease, making daily sequencing as simple as interacting with a smartphone.

Data compression lossless

Reliable Data Management:

Built-in lossless data compression reduces storage and bandwidth needs by up to 5× without compromising accuracy. Intelligent checkpointing ensures sequencing resumes seamlessly after interruptions.

Empower Multi-Omics

Versatility for Multi-Omics:

T7+ supports WGS, spatio-temporal omics, cell-omics, proteomics, epigenomics, transcriptomics, and more, making it adaptable to evolving research and operational needs.

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FAQs
What is a TDI Camera?

A TDI (Time Delay and Integration) camera is a high-performance imaging system used in MGI’s T20×2 ultra-high throughput sequencer to capture fluorescence signals with exceptional sensitivity and speed. Unlike conventional cameras that take static images, a TDI camera continuously scans across the sequencing slide, synchronizing image acquisition with sample movement. This technique integrates multiple exposures of the same area over time, significantly boosting signal strength and reducing noise. In the T20*, the TDI line-scan cameras work alongside a liquid-immersion optical lens and a large field-of-view objective to capture more fluorescence data per unit time with higher resolution. The result is faster, more accurate base identification and greater sequencing throughput — a cornerstone technology enabling MGI’s record-breaking data generation efficiency.

What is DNBSEQ Technology?

DNBSEQ is MGI’s proprietary sequencing platform based on DNA Nanoball (DNB) technology. Instead of traditional bridge amplification used by other platforms, DNBSEQ amplifies DNA fragments through rolling circle replication, creating dense, uniform DNA nanoballs that are then arrayed on a patterned flow cell. This approach eliminates amplification errors, reduces duplication rates, and enhances signal precision. Combined with MGI’s two-color fluorescence detection and advanced imaging systems, DNBSEQ delivers high-throughput, low-cost, and highly accurate sequencing results. The platform supports a wide range of applications—from whole genome and single-cell sequencing to metagenomics and oncology research—while offering superior data consistency and scalability compared to conventional NGS systems.

What is SM 2.0?

Standard MPS 2.0 (SM 2.0) is MGI’s next-generation sequencing chemistry designed to significantly enhance the accuracy and performance of its DNBSEQ™ platforms. By refining enzyme systems, optimizing fluorescent dyes, and improving data interpretation algorithms, SM 2.0 delivers exceptional sequencing quality—achieving over 85% of bases at Q40, or 99.99% base-calling accuracy. These advancements reduce noise, improve signal clarity, and minimize bias from upstream preparation. As a result, researchers gain higher confidence in detecting low-frequency mutations, SNPs, and InDels across applications such as whole genome sequencing, single-cell studies, and microbiome analysis. In essence, SM 2.0 sets a new industry standard for precision, reliability, and data quality in high-throughput sequencing.

What happens if there’s a power outage or system interruption during a run?

T7+ features checkpoint resume technology and proactive fault detection, allowing sequencing to continue without data loss once power or system issues are resolved.

How much hands-on time is required per sequencing run?

The 7-in-1 integrated workflow minimizes manual intervention—preparation and monitoring are streamlined, so staff can focus on data analysis rather than instrument operation.

Can T7+ handle varying sample volumes or project scales?

Yes. The modular QUAD-Flow Cell system allows independent runs, supporting both small batches and large-scale sequencing without compromising speed or accuracy.

How easy is it to integrate T7+ into an existing lab workflow?

The platform is designed to fit seamlessly into existing operations, with smart guidance, automated data processing, and flexible output formats that simplify downstream analysis.

Ready To Order?
As the authorised distributor for MGI in Australia and New Zealand, Decode Science makes adopting the T7+ effortless. We connect your lab with MGI’s ultra-high-throughput sequencing technology, helping you implement T7+ for faster, more reliable genomic results—with local support and guidance whenever you need it.
MGI Portfolio

DNBSEQ-T1+

Accelerate high-throughput genomic testing with DNBSEQ-T1+

The DNBSEQ-T1+ is one of the fastest T-level benchtop sequencers available globally—built on MGI’s proven DNBSEQ™ technology for accuracy, scalability, and reliability. Designed for clinical and translational genomics labs, the T1+ supports dual flow cell operation, delivering up to 1.2 terabases (Tb) of sequencing data within 24 hours (600 Gb per flow cell).

For laboratories managing time-sensitive or high-volume projects, this means faster turnaround, improved workflow efficiency, and reduced dependence on external bioinformatics infrastructure. The optional integrated bioinformatics module enables automated secondary analysis immediately after sequencing, helping clinicians and molecular pathologists move from raw data to interpretable results without delay.

In practice, DNBSEQ-T1+ helps streamline comprehensive genomic profiling (CGP), oncology testing, and clinical research pipelines—supporting both diagnostic accuracy and operational consistency across runs.

High-Speed, High-Throughput Sequencing

Generate up to 1.2 Tb of data in a single run with dual flow cell operation.

Choose from FCL, FCM, or FCS flow cells to match your throughput needs—from small clinical batches to large oncology cohorts.

Maintain >93% Q30 and >90% Q40 base quality across read lengths up to PE150.

Complete full runs in as little as 7–24 hours, supporting faster reporting and clinical turnaround.

Versatile Applications Across Clinical Genomics

Flexible read lengths (SE50–PE300) suit NIPT, RNA-Seq, oncology panels, WES, WGS, and methylation studies.

Supports coverage depth from 1 Gb to 120 Gb per sample, enabling both targeted assays and whole-genome workflows.

Ideal for translational and precision medicine—from pathogen detection to tumour profiling.

Integrated DNB Make & Load Technology

DNB M&L (Make & Load) module automates DNB preparation and loading directly within the sequencer.

Delivers consistent, contamination-free results with minimal hands-on time.

Each flow cell operates independently, supporting different read lengths or applications in parallel.

Enables an end-to-end “Make–Sequence–Analyse” workflow that saves time and reduces error.

Smart Configurations and Automated Analysis

Available in two setups: DNBSEQ-T1+ RS (flexible throughput) and T1+ ARS (with built-in bioinformatics).

The ARS configuration automatically triggers advanced data analysis post-run, streamlining bioinformatics pipelines.

Simplifies data interpretation for clinicians and molecular pathologists, improving workflow efficiency and diagnostic accuracy.

Chris Wicky

Clinical Genomics Manager - ANZ & Country Manager - NZ

Download the DNBSEQ-T1+ brochure for a complete overview of performance metrics, application data, and configuration options. For guidance on how this platform fits your lab’s workflow, Decode Science can walk you through integration and local support options.
Watch How T1+ Works
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FAQs
How can the DNBSEQ-T1+ support my existing oncology or CGP workflows?

The T1+ integrates seamlessly into oncology and comprehensive genomic profiling (CGP) pipelines, providing the depth and coverage needed for both solid tumour and liquid biopsy applications. With PE150 read lengths and up to 1.2 Tb per run, it supports multi-sample batching without compromising turnaround time.

What data quality can I expect for clinical reporting?

Across all flow cell types, >93% of bases exceed Q30 and >90% exceed Q40, ensuring high-confidence variant detection for SNVs, indels, CNVs, and fusions. This level of consistency reduces the need for re-runs and strengthens the reliability of reported results.

How fast can I expect sequencing results for patient samples?

Depending on the mode, runs complete within 7–24 hours, with automated secondary analysis available immediately post-run on the T1+ ARS configuration. This supports faster clinical reporting and improved patient turnaround.

Does the DNBSEQ-T1+ simplify lab workflows or require extra setup?

The DNB Make & Load module automates DNB preparation within the sequencer, reducing manual steps, contamination risk, and hands-on time. Most labs can run end-to-end sequencing with minimal intervention after library prep.

Can I run different assays on the same instrument?

Yes. Each flow cell operates independently, allowing different read lengths or applications—for example, running oncology panels alongside RNA-Seq or WES on the same instrument without downtime.

Ready To Order?
As the authorised distributor for MGI in Australia and New Zealand, Decode Science makes adopting the DNBSEQ-T1+ effortless. We bridge your lab with MGI’s high-throughput sequencing technology, helping you implement the T1+ for faster, more reliable genomic insights—supported locally whenever you need it.
MGI Portfolio

High Throughput Antibody Production

PRODUCTS

High Throughput Antibody Production

Introducing CHO and HEK293 Antibody Production

Twist Bioscience helps researchers speed up antibody discovery with Express Antibody Production using CHO and HEK293 expression systems. Our high-throughput antibody production platform can generate anywhere from dozens to thousands of antibodies, enabling efficient antibody screening for binding specificity and biophysical properties.

By leveraging Twist’s end-to-end gene-to-protein workflow, you can eliminate common antibody production bottlenecks—saving valuable time and research costs. Starting with Twist Express Genes ensures faster production times and antibodies built entirely from your custom gene sequences.

Key Features

CHO Express Antibodies

  1. From 13 business days*
  2. 1 mL and 8 mL scales available
  3. Average Yields = 640 ug

HEK293 Express Antibodies

  1. From 10 business days*
  2. 1 mL and 8 mL scales available
  3. Average = Yields 760 ug
Why Twist for Antibody Production?

Customization

Design antibodies with optimal binding affinity, specificity, and reduced immunogenicity.

Speed & Efficiency

Rapid, sequence-perfect DNA synthesis accelerates your antibody development timeline.

Scalable Production

From small-scale studies to large-scale drug discovery, scale antibody production with ease.

Cutting-Edge Technology

Access the latest gene synthesis innovations without high costs.

Expert Support

Get 24/7 guidance from antibody design to submission.

You design it. We build it.
IgG Workflow - Antibody Production
What Scientists Have to Say

Wyatt McDonnell

CEO & Founding Scientist • Infinnimune

Using Twist’s solutions saves us hundreds of thousands of dollars annually in labor costs. The cost efficiency of Twist Express Antibodies allows us to test four times as many antibodies each year as we otherwise could.

Dr. Ahuva Nissim

Professor in Antibody and Therapeutic Engineering • Queen Mary University of London

Working with Twist…was a great experience…[Twist’s] support was amazing. We have performed the first validation selections which looks promising…

Pierre Martineau

Deputy Director, Cancer Research Institute of Montpellier • Founder and Scientific Advisor, iMAb

We have performed the first selections using the Fab and scFv libraries. No problem in both cases, we got clones and some look really promising.
Ready To Order?
Our team can help you in placing the order. Click below to get a quote and fast ordering.

Know More About...

Have a question?

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

    Or give us a call at:

    1300 581 991

    Arrayed gRNA Libraries

    PRODUCTS

    Arrayed gRNA Libraries

    Arrayed gRNA Libraries

    Smarter, Faster, and More Efficient CRISPR Screening

    Achieve unparalleled knockout efficiency with EditCo’s multi-guide CRISPR design. Our Arrayed CRISPR gRNA Libraries eliminate the inefficiencies of traditional loss-of-function screens, offering a reliable and ready-to-transfect solution. With up to three spatially coordinated sgRNAs per gene, our approach ensures higher knockout success, reduces false negatives, and eliminates the need for complex NGS data analysis. Designed for both human and mouse genes, our libraries provide fast delivery, robust quality control, and seamless Sanger sequencing analysis—so you can focus on results, not troubleshooting.

    Whole Genome CRISPR Libraries for Comprehensive Gene Editing

    EditCo’s Whole Human and Whole Mouse Genome Libraries provide unmatched gene coverage with our multi-guide design, ensuring high editing efficiency across 20,000+ gene targets. Designed for seamless transfection, these libraries reduce false negatives and eliminate time-consuming preparation, making large-scale CRISPR screening easier than ever.

    • – Comprehensive Coverage: Target the entire human or mouse genome with high knockout efficiency.
    • – Ready-to-Use Libraries: Pre-plated and transfection-ready, minimizing preparation time.
    • – Enhanced Stability: Chemically modified sgRNAs resist degradation and prevent immune responses.
    • – Flexible Formats: Available in 96- or 384-well plates with multi-guide sgRNAs for reliable gene disruption.
    Accelerate Target Discovery with Pathway Libraries

    EditCo’s 30+ Pathway Libraries, including druggable targets, GPCRs, kinases, and immuno-oncology genes, provide a powerful tool for target identification studies. Designed with our multi-guide CRISPR strategy, these libraries ensure high knockout efficiency and fewer false negatives. Select libraries ship in as little as one week, helping you start your screen faster.

    • – Diverse Pathway Coverage: Includes key gene sets for drug discovery and functional studies.
    • – Fast Shipping: Select libraries ready to ship within a week.
    • – High-Efficiency Knockouts: Multi-guide sgRNAs deliver precise, predictable gene disruption.
    • – Ready-to-Use Format: Available in 96- or 384-well plates with modified sgRNAs for stability.
    Available Gene Pathways
    Optimal Knockout Efficiency for High-Throughput Screening

     

    XDel technology delivers precise, high-efficiency knockouts by using a multi-guide RNA strategy that ensures consistent and reliable gene editing. Unlike traditional single-guide methods, XDel induces fragment deletions in early exons, maximizing on-target accuracy while minimizing variability and off-target effects.

    • Superior editing efficiency – Multi-guide design achieves higher and more consistent knockouts
    • Reduced off-target effects – XDel minimizes unintended edits compared to single-guide methods
    • Sustained knockout effects – Gene edits remain stable across multiple cell passages
    • High viability & protein depletion – Maintains cell health while ensuring effective functional knockouts

    Achieve robust genotype and phenotype screening with XDel’s optimized CRISPR knockout technology.

    XDel multiple gRNA creates fragment deletions

    Image: XDel multiple gRNA creates fragment deletions

    Image: XDel design includes up to 3 modified sgRNAs (grey bars) that target a single gene of interest

    Ready to Order?
    Our team can help you in placing the order. Click below to get a quote and fast ordering.
    Ready to Order?

    Let’s Find You an Application That Helps Your Research

    Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

      Or give us a call at:

      1300 581 991

      Gene Knockout Kits

      EditCo Gene Knockout Kits: Reliable and Efficient CRISPR Solutions

      EditCo’s Gene Knockout Kit offers a simplified, highly efficient solution for generating human and mouse protein-coding gene knockouts.

      Unlike traditional CRISPR methods, which rely on a single guide RNA (gRNA) to create random indels, EditCo’s multi-guide approach ensures consistent and precise gene disruption. This method generates fragment deletions at the targeted loci, providing a more reliable and predictable knockout, ultimately enhancing experimental success.

      With fast delivery times (kits arrive in just 5 days), users can avoid the trial and error of guide screening and proceed quickly with their experiments. The process is streamlined further with an easy online ordering portal, which includes the option to purchase controls, SpCas9 nuclease, and Transfection Optimization kits to complement your knockout experiment.

      This solution guarantees high knockout efficiency, making gene editing faster and more reliable than ever before.

      Why It Matters

      Maximise Gene Disruption

      XDel’s multi-guide CRISPR design consistently delivers higher on-target editing across multiple loci and cell types. By coordinating 2–3 sgRNAs per exon, researchers can achieve complete functional knockouts with minimal variability.

      Precision Editing with Minimal Risk

      Off-target edits are a major concern in gene editing. XDel’s cooperative guide approach allows for lower gRNA concentrations while maintaining efficiency, reducing unintended edits and improving experimental reliability.

      Persistent Protein Depletion, Straight to Assays

      Edited cell pools maintain stable protein loss for weeks, enabling direct use in downstream functional assays. This reduces validation cycles and accelerates your research timelines.

      Why Traditional Knockouts Fall Short

      Despite its power, CRISPR-Cas9 isn’t foolproof. Most conventional knockout strategies rely on a single guide RNA to induce a small insertion or deletion (indel) at the target site. In theory, this should disrupt the reading frame and deactivate the gene — but in practice, it rarely works that cleanly.

      Even minor indels can restore partial functionality or trigger alternative splicing, leaving residual protein activity that undermines downstream results. What should be a “complete knockout” often ends up a mosaic of mixed edits, forcing researchers to spend additional time validating, recloning, or repeating experiments.

      And it doesn’t stop there — when working with complex or sensitive cell models like iPSCs, low editing efficiency and variable expression recovery make reproducibility a constant battle. The result? Weeks lost, inconsistent phenotypes, and data that’s difficult to interpret or publish.

      Researchers need more than chance-based gene disruption.
      They need an approach that targets with precision, edits consistently across cell types, and produces true functional knockouts the first time.

      That’s exactly where XDel Technology steps in.

      XDel Technology – Coordinated, Multi-Guide Editing

      Traditional CRISPR depends on a single cut — a gamble on where repair enzymes will introduce small, random indels. XDel takes a fundamentally smarter approach.

      Instead of one guide, XDel uses up to three sgRNAs targeting sites within the same exon. These guides work together to generate coordinated fragment deletions, ensuring the targeted region is fully removed rather than partially disrupted. The result is a true functional knockout — not a mixture of partial edits.

      This multi-guide design provides several key advantages:

      • Higher knockout efficiency: Coordinated cuts increase the likelihood of complete loss of gene function across all alleles.

      • Cleaner edit outcomes: Large, predictable deletions are easier to confirm with standard PCR or sequencing, reducing downstream validation time.

      • Compatibility across cell types: Proven performance in immortalized, primary, and iPSC models — even those typically resistant to editing.

      By shifting from random indels to engineered deletions, XDel dramatically improves experimental reproducibility and shortens the path from edit design to verified knockout.

      Hamza Hassan

      Business Development Manager- Research and Applied

      Whether your work is in functional genomics, disease modeling, or drug discovery, XDel technology helps you achieve reproducible results faster and with less rework. Decode Science is the official Australian distributor of EditCo. So feel free to reach out to me if you have any questions.
      Data-Proven Performance

      XDel isn’t theory — it’s backed by real, quantitative data across multiple loci and cell types.

      In comparative studies of seven endogenous genes across four different cell lines, XDel’s multi-guide approach consistently outperformed conventional single-guide designs in both knockout efficiency and edit consistency.

      1. Higher and More Consistent On-Target Editing

      Traditional single-guide methods introduce random indels that often yield partial or incomplete knockouts.
      XDel solves this by deploying up to three predesigned sgRNAs targeting a single exon, working together to generate large fragment deletions.
      Across seven endogenous loci in four cell lines, this approach achieved significantly higher and more consistent editing efficiencies — reducing the rework often required in CRISPR experiments.

      On target Editing of XDel vs Single guide Knockout Cells
      2. Stable Protein Depletion Across Time

      Effective gene disruption means sustained loss of protein function, not just transient edits.
      In K562 cells, XDel-mediated knockouts of four membrane proteins maintained stable protein depletion for up to 21 days post-editing — with >90% cell viability throughout.
      These pools are immediately assay-ready, eliminating the need for additional validation or re-editing.

      Click on image to view full size

      3. Fewer Off-Target Edits, Greater Precision

      A key concern with multi-guide systems is off-target activity — but XDel’s design delivers the opposite.
      Rigorous NGS analysis across 63 off-target loci confirmed that XDel edits are more precise than single-guide approaches, showing markedly lower off-target frequencies across both immortalized and iPSC lines.

      Off target Editing of XDel vs Single Guide Knockout cells
      Off target editing across 46 off-target site in 4 immortalized or iPS cell lines
      4. Confirmed Protein Knockout Across Multiple Genes

      Western blot analyses for five independent target genes confirmed complete and consistent protein depletion at days 7, 14, and 21 post-transfection.
      This demonstrates that XDel doesn’t just produce edits — it reliably eliminates functional protein expression across diverse gene targets.

      Protein Depletion - Gene Knockout Cells
      5. High Editing Efficiency at Lower gRNA Concentrations

      The cooperative behavior of XDel’s multi-guide system enables lower total gRNA usage while maintaining exceptional on-target editing rates.
      Even when RNP concentrations were reduced to 0.25×, editing remained high with minimal off-target impact — translating to more cost-efficient and cleaner edits.

      High Editing Efficiency at Lower gRNA Concentrations
      Applications Across Research Areas

      Functional Genomics

      Disease Modeling

      Drug Discovery and Target Validation

      CRISPR Screening and High-Throughput Studies

      Talk to Our Specialist
       

      Decode Science is the official distributor of EditCo in Australia and New Zealand, helping researchers access XDel Knockout Technology with local expertise and technical support. Our team works alongside you to identify the right solutions for your workflow — from targeted knockouts to large-scale CRISPR screens — backed by EditCo’s proven data and Decode’s commitment to reproducibility.

      For more information or project-specific guidance, reach out to Hamza Hassan, our business development manager, to discuss how XDel can accelerate your next experiment.

      CRISPR Reagents Portfolio

      Knockout T-cells

      PRODUCTS

      Knockout CD8+ & CD4+ T Cells

      Knockout Tcells

      Advanced CRISPR Knock-Ins for iPSC Research

      EditCo delivers efficient gene editing with guaranteed >80% efficiency in human primary cells, achieving >90% in many cases, using a smart multi-guide design and a 7-day protocol for results in 2 weeks or faster. Their Primary Cell KO Pools produce functionally consistent cell populations, ideal for drug discovery or biological modeling, while maintaining high viability and functionality. Researchers can use EditCo-supplied cells or their own CD8+/CD4+ T cells, ensuring flexibility and reliability. By minimizing failed experiments and false negatives, EditCo saves time and resources, offering 1M-cell EC Pools for high-quality, rapid, and dependable gene editing.

      EditCo Knockout Immortalized Cells

      Focus on your experiment while they handle CRISPR

      Their KO Primary T-cells ensure >80% editing efficiency, available with EditCo-supplied cells or your own experimental/clinical samples.

      Choose your starting point

      Options include EditCo-supplied cells or customer-provided samples, with edits available for single knockouts using multi-guide synthetic sgRNA.

      Transparent and detailed results

      Receive regular updates, 2 vials of edited cell pools (>1M cells/vial), control-transfected pools, gRNA sequences, NGS primers, sequencing reports, and a detailed QC analysis.

      Reliable and validated outcomes

      Each order includes a QC report with mycoplasma testing, passage number, and NGS analysis to ensure high-quality, functional edited cells.

      Image: High editing efficiency across multiple donors.

      Image: EditCo KO CD8+ T cell pools can be thawed and expanded for weeks, with or without TCR stimulation.

      Next-Level Edited CD8+ T Cells – Powerful, Stable, and Ready for Action

      Take your research further with precision-engineered CD8+ T cells that combine high editing efficiency, long-term stability, and exceptional functionality. Designed to maintain their knockout integrity, expand effortlessly post-thaw, and deliver strong antigen-specific responses, these cells are built for performance. Whether you’re exploring immune responses or advancing cell therapy, these edited T cell pools provide the reliability and power you need.

       

      🔬 Unmatched Editing Precision – Achieve over 90% knockout efficiency across multiple donors, maintaining stability before and after cryopreservation.

      🧬 Thrives & Expands with Ease – These cells stay healthy and proliferate for weeks, with or without stimulation, ensuring flexibility in your experiments.

      Optimized for Real-World Function – A single round of activation preserves normal function, preventing overstimulation and exhaustion.

      🎯 Potent, Targeted Cytotoxicity – Strong antigen-specific activation, with robust CD107a expression, ensures effective tumor-killing potential.

       

      Power up your research with CD8+ T cells engineered to perform when it matters most.

      CD4+ T Cells - Stability and Functionality Post-Editing

      The editing of CD4+ T cells has shown high efficiency and stability, with a robust ability to maintain functionality after the editing process. The efficiency of the CD4+ T cell editing was determined through ICE analysis, with results demonstrating high editing efficacy across multiple loci while ensuring cell viability during the freezing stage. Post-editing, the cells can be thawed and expanded without loss of functionality or editing efficiency. Cytokine production in edited T cells, including IFNg, IL2, and TNFa, indicates that the editing process does not negatively impact the cells’ ability to produce essential cytokines upon stimulation. These edited pools also show high viability, making them suitable for further downstream assays.

      • – High editing efficiency of CD4+ T cells determined by ICE analysis.
      • – No reduction in cell viability after freezing, as indicated by flow cytometry
      • – Successful expansion and thawing of edited cells without affecting functionality
      • – Edited cells exhibit high levels of cytokine production (IFNg, IL2, TNFa) post-stimulation 
      • – High viability and expansion potential, with >90% viability after 14 days in culture 
      • – Statistical analysis shows significant cytokine differences between edited and mock cells 

      Image: Editing Efficiency and Viability for CD4+ T cell pools.

      Image: Editing Efficiency leads to protein depletion as shown by flow cytometry

      Image: CD4+ pool stability after thaw.

      Ready to Order?
      Our team can help you in placing the order. Click below to get a quote and fast ordering.

      Let’s Find You an Application That Helps Your Research

      Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

        Or give us a call at:

        1300 581 991

        Knockout Immortalized Cells

        PRODUCTS

        Knockout Immortalized Cells

        Knock-in Immortalized Cell Lines

        Reliable, Reproducible CRISPR Editing for Breakthrough Discoveries

        Spend Less Time on Editing, More on Innovation: EditCo’s advanced automation eliminates time-consuming steps, allowing you to focus on impactful research.

        Superior Performance & Scalability: Our CRISPR platform delivers high knockout efficiencies, ensuring consistent, reproducible results across experiments.

        EditCo Knockout Immortalized Cells

        Characterize Genes Associated with Neurodegenerative Disease:

        Develop immortalized cell line models to uncover and characterize genes involved in Parkinson’s Disease.

        Investigate a Protein’s Mechanism of Action:

        Accelerate your data generation with high-quality reagents that avoid high off-target issues to quickly and confidently confirm protein function.

        Expedite Drug Discovery
        Research:

        Validate a new drug lead without having to invest time learning or optimizing CRISPR.

        Thoroughly Confirm Your Phenotype in Multiple Models in Parallel:

        Generate data in time for your next board meeting or publication by running assays in parallel to identify your targets.

        XDel Knockout Cell Pools & Clones - EditCo | Decode Science
        XDel Knockout Cell Pools & Clones

        XDel is an advanced CRISPR knockout tool that eliminates uncertainty in gene editing. Using a groundbreaking guide RNA design approach, it provides highly effective, reliable, and repeatable gene knockouts, enabling researchers to speed up their breakthroughs with assurance.

        • – Higher Efficiency & Consistency: XDel technology ensures superior on-target knockout rates with minimal variability.
        • – Reduced Off-Target Effects: Achieve precise edits with lower unintended mutations compared to single-guide methods.
        • – Validated & Scalable: Persistent protein depletion enables direct use in functional assays, drug discovery, and disease modeling.
        CRISPR Knockout Cell Pools & Clones
        CRISPR Knockout Cell Pools & Clones

        Accelerate your research with high-efficiency CRISPR Knockout Cell Pools & Clones from EditCo. Our cell pools provide a mix of edited and unedited cells for immediate assays, while clonal lines ensure precise gene knockouts with sequence-verified accuracy.

        • – 50%+ knockout efficiency in cell pools
        • – Up to 95% protein knockout for functional validation
        • – Single, double, or triple knockouts available
        • – Comprehensive QC & sequencing reports included
        Knockout Cell Libraries – High-Throughput CRISPR Screening Made Easy

        EditCo’s Knockout Cell Libraries enable high-efficiency CRISPR screening with over 90% editing success in a ready-to-use 96-well arrayed format. Designed for functional assays and drug target discovery, our libraries eliminate transfection challenges and infrastructure barriers.

        • Multi-guide CRISPR design for precise knockouts
        • High-throughput screening with scalable workflows
        • – Comprehensive QC & sequencing reports included
        • – Compatible with diverse assays for discovery & validation
        Knockout Cell Libraries – High-Throughput CRISPR Screening Made Easy
        Ready to Order?
        Our team can help you in placing the order. Click below to get a quote and fast ordering.
        Immortalized Cells Portfolio

        Let’s Find You an Application That Helps Your Research

        Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

          Or give us a call at:

          1300 581 991

          Knock-in iPS Cells

          PRODUCTS

          Knock-in iPS Cells

          iPSC_min

          Advanced CRISPR Knock-Ins for iPSC Research

          EditCo’s advanced CRISPR knock-ins empower neuroscience, cardiovascular, and regenerative medicine research by delivering precise edits in iPSCs while maintaining their quality, pluripotency, and integrity. Our high-throughput automated platform ensures fast lead times and high editing efficiencies, allowing you to focus on downstream applications like assay development and differentiation.

          With minimal off-target effects, our platform offers a range of knock-ins, including single nucleotide variants, tags, and small insertions (<100 bp), available in both homozygous and heterozygous states, as well as in clone or pool formats. Trust EditCo’s robust editing process to accelerate your discoveries with artifact-free, reliable CRISPR-edited iPSCs.

          Knock-in Immortalized Cells

          Isogenic Neuronal Lines:

          Create isogenic neuronal lines by reverting disease SNV genotypes to wild type with CRISPR-edited iPSCs.

          Drug Screening:

          Enhance drug screening with gene-corrected control lines for disease-relevant cell types.

          Protein Tagging:

          Tag target proteins to study subcellular localization under endogenous regulation.

          Disease Modeling:

          Model mutations in disease-relevant cell types using high-quality edited iPSCs.

          iPS cells were assessed for standard pluripotency markers

          Image: iPS cells were assessed for standard pluripotency markers, three days post-editing.

          Single-guide RNA Knock-in Cell Pools

          Achieve high-efficiency CRISPR iPSC knock-ins with EditCo’s Knock-in iPS Cell Pools. These pools offer a mix of edited and unedited cells, giving you flexibility for clonal isolation. Our optimized platform ensures precise edits, while you have the option to perform clonal isolation yourself. For those looking for a fully automated process, explore our Knock-in iPS Cell Clones for homogeneity and convenience.

          Features:

          • – Cell Source: EditCo or customer supplied
          • – Available Edits: SNV, Tag, or Insertion
          • – CRISPR Design: Synthetic modified sgRNA, Donor ssODN
          • – Add-ons: QC for pluripotency testing

          Deliverables:

          • Edited cell pools (2 vials with 5 million cells)
          • Regular updates, sequencing data, and comprehensive QC reports

          EditCo ensures robust editing with high efficiency across a variety of iPSC lines, maintaining pluripotency and delivering consistent, reliable results.

          Single-guide RNA Knock-in Cell Clones

          EditCo’s Knock-in iPS Cell Clones provide homogeneous populations derived from single CRISPR-edited cells. Skip the editing and cloning process, and move directly into functional assays with high-quality, reliable clones. We manage the entire CRISPR editing and cloning process, ensuring you receive precise, genetically modified clones for accelerated research.

          Features:

          • – Cell Source: EditCo or customer supplied
          • – Genetic Modifications: SNV, Tag, or Insertion (Homozygous or Heterozygous)
          • – CRISPR Design: Synthetic modified sgRNA, Donor ssODN
          • – Add-ons: Additional clones, QC for pluripotency and karyotype testing

          Deliverables:

          • 2 independent clones with the required knock-in (2 vials of 500,000 cells each)
          • Regular progress updates, sequencing data, and comprehensive QC reports

          EditCo ensures precise SNV editing and delivers reliable, pluripotent clones ready for your downstream applications.

          SNV editing in iPS cell clones

          Image: 100% SNV editing in iPS cell clones.

          Use EditCo’s iPS Cell Lines or Bring Your Own
          EditCo provides iPS cell lines for all engineered cell orders at no extra cost. Alternatively, you can onboard your own cell lines.

          EditCo-supplied cell lines

          * Parental vials available for evaluation prior to booking an edit

          Ready to Order?
          Our team can help you in placing the order. Click below to get a quote and fast ordering.
          IPS Cells Portfolio

          Let’s Find You an Application That Helps Your Research

          Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

            Or give us a call at:

            1300 581 991

            Knockout iPS Cells

            PRODUCTS

            Knockout iPS Cells

            Knockout iPS Cells

            Precise and efficient models for cutting-edge disease research.

            EditCo’s cutting-edge CRISPR technology ensures accurate and efficient gene editing while maintaining iPSC quality, pluripotency, and overall cell integrity. Our automated platform, optimized guide design, and superior reagents enable high-efficiency knock-ins and knockouts, minimizing errors and off-target effects. With a focus on delivering reliable and functional gene modifications, our robust process allows researchers to confidently assay gene functions, model diseases, and explore new therapeutic targets.

            Whether you need precise knockouts or complex knock-ins, EditCo’s advanced editing solutions provide the accuracy and consistency required for high-impact scientific discoveries in biomedical research.

            Knock-in Immortalized Cells

            Gene Function Studies:

            Disrupt your target gene to assess its role in a phenotype or cellular function.

            Gene-Disease Linkage:

            Investigate genetic factors in neurodegenerative diseases using edited iPSCs and neuronal cell types.

            Pathway Analysis:

            Knock out genes in your disease pathway. Differentiate cells into disease-relevant types and test for drug targets.

            Target Validation:

            Validate targets in CRISPR-edited iPSCs to confirm gene-disease linkage in cell models.

            Single Guide Pools Results
            XDel Knockout Cell Pools and Clones

            XDel is a CRISPR technology for precise, efficient gene editing. With a unique guide RNA design, it ensures reproducible knockouts without affecting pluripotency or cell integrity, accelerating research in gene function, disease modeling, and drug development.

            • – High Efficiency: Superior editing and consistent knockouts.
            • – Reliable Results: Persistent protein depletion validated through assays.
            • – Reproducibility: Minimized variability for dependable outcomes.
            XDel Knockout Cell Pools & Clones - EditCo | Decode Science
            XDel multiple guide RNA off-target editing efficiency

            Features

            • – Cell Source: EditCo or customer supplied.
            • – Available Edits: Indel, fragment deletion, homozygous, or heterozygous.
            • – Design: Synthetic modified sgRNA.
            • – Add-Ons: Additional clones, testing.
            • – Deliverables: Updates, edited cell pools (2 vials), sequencing data, and QC reports.

            Superior Editing
            XDel offers more consistent and efficient on-target editing than single-guide RNA methods, ensuring reliable results.

            Reduced Off-Target Effects
            XDel delivers lower off-target editing compared to single-guide RNA, ensuring better precision.

            Robust Knockouts
            XDel pools maintain genomic stability, confirmed by karyotyping and PluriTest™.

            How XDel Works
            XDel uses up to 3 coordinated guides for reliable knockouts, offering more consistent edits than traditional single-guide methods.

            XDel pools and clones
            Multi-guide schematic-new
            Ready to Order?
            Our team can help you in placing the order. Click below to get a quote and fast ordering.
            IPS Cells Portfolio

            Let’s Find You an Application That Helps Your Research

            Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

              Or give us a call at:

              1300 581 991

              Knock-in Immortalized Cells

              PRODUCTS

              Knock-in Immortalized Cells

              Arrayed CRISPR sgRNA Libraries

              Get CRISPR-Engineered Cell Lines Faster and More Efficiently.

              EditCo’s Knock-in Immortalized Cells provide a fast and efficient way to integrate engineered cells into your research, using automated transfection optimization and RNP-based delivery to ensure high editing success with minimal off-target effects.

              By eliminating the delays and challenges of DIY CRISPR projects, our cost-effective solution enables you to model more genes and variants across multiple cell lines, accelerating your path to discovery without overspending.

              Knock-in Immortalized Cells

              Tag and Quantify Your Protein:

              Easily purify and measure your target protein with
              precise tagging.

              Create a Disease Model:

              Modify genes to introduce or correct mutations for studying disease phenotypes.

              Analyze Gene Regulation:

              Develop reporter cell lines with promoter tags to monitor
              gene activity.

              Uncover Protein Interactions:

              Use affinity tags to map protein-protein interactions and identify key partners.

              Single Guide Pools Results
              Cost-Effective CRISPR Knock-in Cell Pools – Flexible & Efficient

              EditCo’s Knock-in Immortalized Cell Pools provide a high-throughput, budget-friendly solution for introducing precise edits while maintaining a mixed population of edited and unedited cells.

              • – Optimized transfection for high-efficiency knock-ins
              • – Supports SNVs, tags, and large insertions with advanced HDR strategies
              • – Flexible clonal isolation—manage it yourself or opt for our Knock-in Clones
              • – Comprehensive QC & sequencing reports for reliable validation
              Precision-Verified CRISPR Knock-in Clones – Ready for Your Research

              EditCo’s Knock-in Immortalized Cell Clones provide a sequence-verified, clonal population for precise, high-quality knock-ins. Whether modifying SNVs, tagging proteins, or inserting large sequences, our automated isolation process ensures you receive a single-cell-derived clone with your desired edit.

              • – Guaranteed precision with fully validated knock-ins
              • – Endogenous tagging & SNV editing for functional studies
              • – Streamlined delivery with complete QC & sequencing reports
              • – Customizable options including additional clones & intermediate pools

              Skip the complexity—get ready-to-use, precision-edited clones with EditCo!

              Ready to Order?
              Our team can help you in placing the order. Click below to get a quote and fast ordering.
              Immortalized Cells Portfolio

              Let’s Find You an Application That Helps Your Research

              Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

                Or give us a call at:

                1300 581 991