High Throughput Antibody Production

PRODUCTS

High Throughput Antibody Production

Introducing CHO and HEK293 Antibody Production

Twist Bioscience helps researchers speed up antibody discovery with Express Antibody Production using CHO and HEK293 expression systems. Our high-throughput antibody production platform can generate anywhere from dozens to thousands of antibodies, enabling efficient antibody screening for binding specificity and biophysical properties.

By leveraging Twist’s end-to-end gene-to-protein workflow, you can eliminate common antibody production bottlenecks—saving valuable time and research costs. Starting with Twist Express Genes ensures faster production times and antibodies built entirely from your custom gene sequences.

Key Features

CHO Express Antibodies

  1. From 13 business days*
  2. 1 mL and 8 mL scales available
  3. Average Yields = 640 ug

HEK293 Express Antibodies

  1. From 10 business days*
  2. 1 mL and 8 mL scales available
  3. Average = Yields 760 ug
Why Twist for Antibody Production?

Customization

Design antibodies with optimal binding affinity, specificity, and reduced immunogenicity.

Speed & Efficiency

Rapid, sequence-perfect DNA synthesis accelerates your antibody development timeline.

Scalable Production

From small-scale studies to large-scale drug discovery, scale antibody production with ease.

Cutting-Edge Technology

Access the latest gene synthesis innovations without high costs.

Expert Support

Get 24/7 guidance from antibody design to submission.

You design it. We build it.
IgG Workflow - Antibody Production
What Scientists Have to Say

Wyatt McDonnell

CEO & Founding Scientist • Infinnimune

Using Twist’s solutions saves us hundreds of thousands of dollars annually in labor costs. The cost efficiency of Twist Express Antibodies allows us to test four times as many antibodies each year as we otherwise could.

Dr. Ahuva Nissim

Professor in Antibody and Therapeutic Engineering • Queen Mary University of London

Working with Twist…was a great experience…[Twist’s] support was amazing. We have performed the first validation selections which looks promising…

Pierre Martineau

Deputy Director, Cancer Research Institute of Montpellier • Founder and Scientific Advisor, iMAb

We have performed the first selections using the Fab and scFv libraries. No problem in both cases, we got clones and some look really promising.
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    Arrayed gRNA Libraries

    PRODUCTS

    Arrayed gRNA Libraries

    Arrayed gRNA Libraries

    Smarter, Faster, and More Efficient CRISPR Screening

    Achieve unparalleled knockout efficiency with EditCo’s multi-guide CRISPR design. Our Arrayed CRISPR gRNA Libraries eliminate the inefficiencies of traditional loss-of-function screens, offering a reliable and ready-to-transfect solution. With up to three spatially coordinated sgRNAs per gene, our approach ensures higher knockout success, reduces false negatives, and eliminates the need for complex NGS data analysis. Designed for both human and mouse genes, our libraries provide fast delivery, robust quality control, and seamless Sanger sequencing analysis—so you can focus on results, not troubleshooting.

    Whole Genome CRISPR Libraries for Comprehensive Gene Editing

    EditCo’s Whole Human and Whole Mouse Genome Libraries provide unmatched gene coverage with our multi-guide design, ensuring high editing efficiency across 20,000+ gene targets. Designed for seamless transfection, these libraries reduce false negatives and eliminate time-consuming preparation, making large-scale CRISPR screening easier than ever.

    • – Comprehensive Coverage: Target the entire human or mouse genome with high knockout efficiency.
    • – Ready-to-Use Libraries: Pre-plated and transfection-ready, minimizing preparation time.
    • – Enhanced Stability: Chemically modified sgRNAs resist degradation and prevent immune responses.
    • – Flexible Formats: Available in 96- or 384-well plates with multi-guide sgRNAs for reliable gene disruption.
    Accelerate Target Discovery with Pathway Libraries

    EditCo’s 30+ Pathway Libraries, including druggable targets, GPCRs, kinases, and immuno-oncology genes, provide a powerful tool for target identification studies. Designed with our multi-guide CRISPR strategy, these libraries ensure high knockout efficiency and fewer false negatives. Select libraries ship in as little as one week, helping you start your screen faster.

    • – Diverse Pathway Coverage: Includes key gene sets for drug discovery and functional studies.
    • – Fast Shipping: Select libraries ready to ship within a week.
    • – High-Efficiency Knockouts: Multi-guide sgRNAs deliver precise, predictable gene disruption.
    • – Ready-to-Use Format: Available in 96- or 384-well plates with modified sgRNAs for stability.
    Available Gene Pathways
    Optimal Knockout Efficiency for High-Throughput Screening

     

    XDel technology delivers precise, high-efficiency knockouts by using a multi-guide RNA strategy that ensures consistent and reliable gene editing. Unlike traditional single-guide methods, XDel induces fragment deletions in early exons, maximizing on-target accuracy while minimizing variability and off-target effects.

    • Superior editing efficiency – Multi-guide design achieves higher and more consistent knockouts
    • Reduced off-target effects – XDel minimizes unintended edits compared to single-guide methods
    • Sustained knockout effects – Gene edits remain stable across multiple cell passages
    • High viability & protein depletion – Maintains cell health while ensuring effective functional knockouts

    Achieve robust genotype and phenotype screening with XDel’s optimized CRISPR knockout technology.

    XDel multiple gRNA creates fragment deletions

    Image: XDel multiple gRNA creates fragment deletions

    Image: XDel design includes up to 3 modified sgRNAs (grey bars) that target a single gene of interest

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    Ready to Order?

    Let’s Find You an Application That Helps Your Research

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      Gene Knockout Kits

      PRODUCTS

      Gene Knockout Kits

      national-cancer-institute-c-wqrSCjVf4-unsplash (2)

      EditCo Gene Knockout Kits: Reliable and Efficient CRISPR Solutions

      EditCo’s Gene Knockout Kit offers a simplified, highly efficient solution for generating human and mouse protein-coding gene knockouts. Unlike traditional CRISPR methods, which rely on a single guide RNA (gRNA) to create random indels, EditCo’s multi-guide approach ensures consistent and precise gene disruption. This method generates fragment deletions at the targeted loci, providing a more reliable and predictable knockout, ultimately enhancing experimental success. With fast delivery times (kits arrive in just 5 days), users can avoid the trial and error of guide screening and proceed quickly with their experiments. The process is streamlined further with an easy online ordering portal, which includes the option to purchase controls, SpCas9 nuclease, and Transfection Optimization kits to complement your knockout experiment. This solution guarantees high knockout efficiency, making gene editing faster and more reliable than ever before.

      Gene knockout cells

      Human and Mouse Knockouts

      Guaranteed for human and mouse genes (excluding non-essential genes), ensuring high knockout efficiency.

      Multi-Guide sgRNA

      Chemically modified sgRNA resists degradation and prevents immune responses for reliable gene editing.

      Complete CRISPR Solution

      Optional add-ons like the Transfection Optimization Kit, SpCas9 nuclease, and controls for a comprehensive experiment.

      Kit Contents

      Includes multiguide sgRNA, SpCas9 EZ Scaffold, buffers, water, and quality control documents for PCR and sequencing.

      Guaranteed Knockouts with Multi-Guide CRISPR

      EditCo’s Gene Knockout Kit uses a multi-guide gRNA approach to ensure reliable and efficient gene disruption. This method targets a single exon with three spatially coordinated gRNAs, creating multiple double-strand breaks and resulting in large fragment deletions. Compared to single-guide CRISPR, our multi-guide strategy significantly increases knockout efficiency, with over 75% large deletions and a 29.2% improvement in knockout success.

      • – High Knockout Efficiency: Multi-guide format provides up to 89.9% knockout success across 32 genetic targets.
      • – Reduced Off-Target Effects: Less occurrence of off-target edits compared to single-guide methods.
      • – Consistent Results: Fragment deletions lead to sustained protein depletion over time, confirmed through Western blot analysis.
      • – Reliable Gene Editing: Achieve complete knockout in just 7 days post-transfection.

      Image: Better knockout efficiency was found across 32 genetic targets assessed.

      Image: EditCo’s Gene Knockout Kit was designed to increase the efficacy of CRISPR-mediated knockouts.

      Image: Multi-guide gRNA for each target resulted in >75% large deletion outcomes.

      Image: Editing of three genes (CDK9, CINP, COASY) in HEK293 cells (transfected via nucleofection) using the multi-guide approach resulted in high knockout efficiencies, as indicated by Knockout (KO) Scores

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      CRISPR Reagents Portfolio

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        Knockout T-cells

        PRODUCTS

        Knockout CD8+ & CD4+ T Cells

        Knockout Tcells

        Advanced CRISPR Knock-Ins for iPSC Research

        EditCo delivers efficient gene editing with guaranteed >80% efficiency in human primary cells, achieving >90% in many cases, using a smart multi-guide design and a 7-day protocol for results in 2 weeks or faster. Their Primary Cell KO Pools produce functionally consistent cell populations, ideal for drug discovery or biological modeling, while maintaining high viability and functionality. Researchers can use EditCo-supplied cells or their own CD8+/CD4+ T cells, ensuring flexibility and reliability. By minimizing failed experiments and false negatives, EditCo saves time and resources, offering 1M-cell EC Pools for high-quality, rapid, and dependable gene editing.

        EditCo Knockout Immortalized Cells

        Focus on your experiment while they handle CRISPR

        Their KO Primary T-cells ensure >80% editing efficiency, available with EditCo-supplied cells or your own experimental/clinical samples.

        Choose your starting point

        Options include EditCo-supplied cells or customer-provided samples, with edits available for single knockouts using multi-guide synthetic sgRNA.

        Transparent and detailed results

        Receive regular updates, 2 vials of edited cell pools (>1M cells/vial), control-transfected pools, gRNA sequences, NGS primers, sequencing reports, and a detailed QC analysis.

        Reliable and validated outcomes

        Each order includes a QC report with mycoplasma testing, passage number, and NGS analysis to ensure high-quality, functional edited cells.

        Image: High editing efficiency across multiple donors.

        Image: EditCo KO CD8+ T cell pools can be thawed and expanded for weeks, with or without TCR stimulation.

        Next-Level Edited CD8+ T Cells – Powerful, Stable, and Ready for Action

        Take your research further with precision-engineered CD8+ T cells that combine high editing efficiency, long-term stability, and exceptional functionality. Designed to maintain their knockout integrity, expand effortlessly post-thaw, and deliver strong antigen-specific responses, these cells are built for performance. Whether you’re exploring immune responses or advancing cell therapy, these edited T cell pools provide the reliability and power you need.

         

        🔬 Unmatched Editing Precision – Achieve over 90% knockout efficiency across multiple donors, maintaining stability before and after cryopreservation.

        🧬 Thrives & Expands with Ease – These cells stay healthy and proliferate for weeks, with or without stimulation, ensuring flexibility in your experiments.

        Optimized for Real-World Function – A single round of activation preserves normal function, preventing overstimulation and exhaustion.

        🎯 Potent, Targeted Cytotoxicity – Strong antigen-specific activation, with robust CD107a expression, ensures effective tumor-killing potential.

         

        Power up your research with CD8+ T cells engineered to perform when it matters most.

        CD4+ T Cells - Stability and Functionality Post-Editing

        The editing of CD4+ T cells has shown high efficiency and stability, with a robust ability to maintain functionality after the editing process. The efficiency of the CD4+ T cell editing was determined through ICE analysis, with results demonstrating high editing efficacy across multiple loci while ensuring cell viability during the freezing stage. Post-editing, the cells can be thawed and expanded without loss of functionality or editing efficiency. Cytokine production in edited T cells, including IFNg, IL2, and TNFa, indicates that the editing process does not negatively impact the cells’ ability to produce essential cytokines upon stimulation. These edited pools also show high viability, making them suitable for further downstream assays.

        • – High editing efficiency of CD4+ T cells determined by ICE analysis.
        • – No reduction in cell viability after freezing, as indicated by flow cytometry
        • – Successful expansion and thawing of edited cells without affecting functionality
        • – Edited cells exhibit high levels of cytokine production (IFNg, IL2, TNFa) post-stimulation 
        • – High viability and expansion potential, with >90% viability after 14 days in culture 
        • – Statistical analysis shows significant cytokine differences between edited and mock cells 

        Image: Editing Efficiency and Viability for CD4+ T cell pools.

        Image: Editing Efficiency leads to protein depletion as shown by flow cytometry

        Image: CD4+ pool stability after thaw.

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        Let’s Find You an Application That Helps Your Research

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          Knockout Immortalized Cells

          PRODUCTS

          Knockout Immortalized Cells

          Knock-in Immortalized Cell Lines

          Reliable, Reproducible CRISPR Editing for Breakthrough Discoveries

          Spend Less Time on Editing, More on Innovation: EditCo’s advanced automation eliminates time-consuming steps, allowing you to focus on impactful research.

          Superior Performance & Scalability: Our CRISPR platform delivers high knockout efficiencies, ensuring consistent, reproducible results across experiments.

          EditCo Knockout Immortalized Cells

          Characterize Genes Associated with Neurodegenerative Disease:

          Develop immortalized cell line models to uncover and characterize genes involved in Parkinson’s Disease.

          Investigate a Protein’s Mechanism of Action:

          Accelerate your data generation with high-quality reagents that avoid high off-target issues to quickly and confidently confirm protein function.

          Expedite Drug Discovery
          Research:

          Validate a new drug lead without having to invest time learning or optimizing CRISPR.

          Thoroughly Confirm Your Phenotype in Multiple Models in Parallel:

          Generate data in time for your next board meeting or publication by running assays in parallel to identify your targets.

          XDel Knockout Cell Pools & Clones - EditCo | Decode Science
          XDel Knockout Cell Pools & Clones

          XDel is an advanced CRISPR knockout tool that eliminates uncertainty in gene editing. Using a groundbreaking guide RNA design approach, it provides highly effective, reliable, and repeatable gene knockouts, enabling researchers to speed up their breakthroughs with assurance.

          • – Higher Efficiency & Consistency: XDel technology ensures superior on-target knockout rates with minimal variability.
          • – Reduced Off-Target Effects: Achieve precise edits with lower unintended mutations compared to single-guide methods.
          • – Validated & Scalable: Persistent protein depletion enables direct use in functional assays, drug discovery, and disease modeling.
          CRISPR Knockout Cell Pools & Clones
          CRISPR Knockout Cell Pools & Clones

          Accelerate your research with high-efficiency CRISPR Knockout Cell Pools & Clones from EditCo. Our cell pools provide a mix of edited and unedited cells for immediate assays, while clonal lines ensure precise gene knockouts with sequence-verified accuracy.

          • – 50%+ knockout efficiency in cell pools
          • – Up to 95% protein knockout for functional validation
          • – Single, double, or triple knockouts available
          • – Comprehensive QC & sequencing reports included
          Knockout Cell Libraries – High-Throughput CRISPR Screening Made Easy

          EditCo’s Knockout Cell Libraries enable high-efficiency CRISPR screening with over 90% editing success in a ready-to-use 96-well arrayed format. Designed for functional assays and drug target discovery, our libraries eliminate transfection challenges and infrastructure barriers.

          • Multi-guide CRISPR design for precise knockouts
          • High-throughput screening with scalable workflows
          • – Comprehensive QC & sequencing reports included
          • – Compatible with diverse assays for discovery & validation
          Knockout Cell Libraries – High-Throughput CRISPR Screening Made Easy
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          Immortalized Cells Portfolio

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            Knock-in iPS Cells

            PRODUCTS

            Knock-in iPS Cells

            iPSC_min

            Advanced CRISPR Knock-Ins for iPSC Research

            EditCo’s advanced CRISPR knock-ins empower neuroscience, cardiovascular, and regenerative medicine research by delivering precise edits in iPSCs while maintaining their quality, pluripotency, and integrity. Our high-throughput automated platform ensures fast lead times and high editing efficiencies, allowing you to focus on downstream applications like assay development and differentiation.

            With minimal off-target effects, our platform offers a range of knock-ins, including single nucleotide variants, tags, and small insertions (<100 bp), available in both homozygous and heterozygous states, as well as in clone or pool formats. Trust EditCo’s robust editing process to accelerate your discoveries with artifact-free, reliable CRISPR-edited iPSCs.

            Knock-in Immortalized Cells

            Isogenic Neuronal Lines:

            Create isogenic neuronal lines by reverting disease SNV genotypes to wild type with CRISPR-edited iPSCs.

            Drug Screening:

            Enhance drug screening with gene-corrected control lines for disease-relevant cell types.

            Protein Tagging:

            Tag target proteins to study subcellular localization under endogenous regulation.

            Disease Modeling:

            Model mutations in disease-relevant cell types using high-quality edited iPSCs.

            iPS cells were assessed for standard pluripotency markers

            Image: iPS cells were assessed for standard pluripotency markers, three days post-editing.

            Single-guide RNA Knock-in Cell Pools

            Achieve high-efficiency CRISPR iPSC knock-ins with EditCo’s Knock-in iPS Cell Pools. These pools offer a mix of edited and unedited cells, giving you flexibility for clonal isolation. Our optimized platform ensures precise edits, while you have the option to perform clonal isolation yourself. For those looking for a fully automated process, explore our Knock-in iPS Cell Clones for homogeneity and convenience.

            Features:

            • – Cell Source: EditCo or customer supplied
            • – Available Edits: SNV, Tag, or Insertion
            • – CRISPR Design: Synthetic modified sgRNA, Donor ssODN
            • – Add-ons: QC for pluripotency testing

            Deliverables:

            • Edited cell pools (2 vials with 5 million cells)
            • Regular updates, sequencing data, and comprehensive QC reports

            EditCo ensures robust editing with high efficiency across a variety of iPSC lines, maintaining pluripotency and delivering consistent, reliable results.

            Single-guide RNA Knock-in Cell Clones

            EditCo’s Knock-in iPS Cell Clones provide homogeneous populations derived from single CRISPR-edited cells. Skip the editing and cloning process, and move directly into functional assays with high-quality, reliable clones. We manage the entire CRISPR editing and cloning process, ensuring you receive precise, genetically modified clones for accelerated research.

            Features:

            • – Cell Source: EditCo or customer supplied
            • – Genetic Modifications: SNV, Tag, or Insertion (Homozygous or Heterozygous)
            • – CRISPR Design: Synthetic modified sgRNA, Donor ssODN
            • – Add-ons: Additional clones, QC for pluripotency and karyotype testing

            Deliverables:

            • 2 independent clones with the required knock-in (2 vials of 500,000 cells each)
            • Regular progress updates, sequencing data, and comprehensive QC reports

            EditCo ensures precise SNV editing and delivers reliable, pluripotent clones ready for your downstream applications.

            SNV editing in iPS cell clones

            Image: 100% SNV editing in iPS cell clones.

            Use EditCo’s iPS Cell Lines or Bring Your Own
            EditCo provides iPS cell lines for all engineered cell orders at no extra cost. Alternatively, you can onboard your own cell lines.

            EditCo-supplied cell lines

            * Parental vials available for evaluation prior to booking an edit

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            IPS Cells Portfolio

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              Knockout iPS Cells

              PRODUCTS

              Knockout iPS Cells

              Knockout iPS Cells

              Precise and efficient models for cutting-edge disease research.

              EditCo’s cutting-edge CRISPR technology ensures accurate and efficient gene editing while maintaining iPSC quality, pluripotency, and overall cell integrity. Our automated platform, optimized guide design, and superior reagents enable high-efficiency knock-ins and knockouts, minimizing errors and off-target effects. With a focus on delivering reliable and functional gene modifications, our robust process allows researchers to confidently assay gene functions, model diseases, and explore new therapeutic targets.

              Whether you need precise knockouts or complex knock-ins, EditCo’s advanced editing solutions provide the accuracy and consistency required for high-impact scientific discoveries in biomedical research.

              Knock-in Immortalized Cells

              Gene Function Studies:

              Disrupt your target gene to assess its role in a phenotype or cellular function.

              Gene-Disease Linkage:

              Investigate genetic factors in neurodegenerative diseases using edited iPSCs and neuronal cell types.

              Pathway Analysis:

              Knock out genes in your disease pathway. Differentiate cells into disease-relevant types and test for drug targets.

              Target Validation:

              Validate targets in CRISPR-edited iPSCs to confirm gene-disease linkage in cell models.

              Single Guide Pools Results
              XDel Knockout Cell Pools and Clones

              XDel is a CRISPR technology for precise, efficient gene editing. With a unique guide RNA design, it ensures reproducible knockouts without affecting pluripotency or cell integrity, accelerating research in gene function, disease modeling, and drug development.

              • – High Efficiency: Superior editing and consistent knockouts.
              • – Reliable Results: Persistent protein depletion validated through assays.
              • – Reproducibility: Minimized variability for dependable outcomes.
              XDel Knockout Cell Pools & Clones - EditCo | Decode Science
              XDel multiple guide RNA off-target editing efficiency

              Features

              • – Cell Source: EditCo or customer supplied.
              • – Available Edits: Indel, fragment deletion, homozygous, or heterozygous.
              • – Design: Synthetic modified sgRNA.
              • – Add-Ons: Additional clones, testing.
              • – Deliverables: Updates, edited cell pools (2 vials), sequencing data, and QC reports.

              Superior Editing
              XDel offers more consistent and efficient on-target editing than single-guide RNA methods, ensuring reliable results.

              Reduced Off-Target Effects
              XDel delivers lower off-target editing compared to single-guide RNA, ensuring better precision.

              Robust Knockouts
              XDel pools maintain genomic stability, confirmed by karyotyping and PluriTest™.

              How XDel Works
              XDel uses up to 3 coordinated guides for reliable knockouts, offering more consistent edits than traditional single-guide methods.

              XDel pools and clones
              Multi-guide schematic-new
              Ready to Order?
              Our team can help you in placing the order. Click below to get a quote and fast ordering.
              IPS Cells Portfolio

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                Knock-in Immortalized Cells

                PRODUCTS

                Knock-in Immortalized Cells

                Arrayed CRISPR sgRNA Libraries

                Get CRISPR-Engineered Cell Lines Faster and More Efficiently.

                EditCo’s Knock-in Immortalized Cells provide a fast and efficient way to integrate engineered cells into your research, using automated transfection optimization and RNP-based delivery to ensure high editing success with minimal off-target effects.

                By eliminating the delays and challenges of DIY CRISPR projects, our cost-effective solution enables you to model more genes and variants across multiple cell lines, accelerating your path to discovery without overspending.

                Knock-in Immortalized Cells

                Tag and Quantify Your Protein:

                Easily purify and measure your target protein with
                precise tagging.

                Create a Disease Model:

                Modify genes to introduce or correct mutations for studying disease phenotypes.

                Analyze Gene Regulation:

                Develop reporter cell lines with promoter tags to monitor
                gene activity.

                Uncover Protein Interactions:

                Use affinity tags to map protein-protein interactions and identify key partners.

                Single Guide Pools Results
                Cost-Effective CRISPR Knock-in Cell Pools – Flexible & Efficient

                EditCo’s Knock-in Immortalized Cell Pools provide a high-throughput, budget-friendly solution for introducing precise edits while maintaining a mixed population of edited and unedited cells.

                • – Optimized transfection for high-efficiency knock-ins
                • – Supports SNVs, tags, and large insertions with advanced HDR strategies
                • – Flexible clonal isolation—manage it yourself or opt for our Knock-in Clones
                • – Comprehensive QC & sequencing reports for reliable validation
                Precision-Verified CRISPR Knock-in Clones – Ready for Your Research

                EditCo’s Knock-in Immortalized Cell Clones provide a sequence-verified, clonal population for precise, high-quality knock-ins. Whether modifying SNVs, tagging proteins, or inserting large sequences, our automated isolation process ensures you receive a single-cell-derived clone with your desired edit.

                • – Guaranteed precision with fully validated knock-ins
                • – Endogenous tagging & SNV editing for functional studies
                • – Streamlined delivery with complete QC & sequencing reports
                • – Customizable options including additional clones & intermediate pools

                Skip the complexity—get ready-to-use, precision-edited clones with EditCo!

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                Immortalized Cells Portfolio

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                  SR-X™ Biomarker Detection System

                  PRODUCTS

                  SR-X™ Biomarker Detection System

                  THE SR-X™ BIOMARKER DETECTION SYSTEM

                  The SR-X Ultra-Sensitive Biomarker Detection System leverages advanced Simoa® bead technology to provide researchers with a compact, cost-effective solution for ultra-sensitive biomarker detection. Designed for multiplexing, the SR-X can detect up to four analytes per well with minimal sample volume, optimizing both productivity and sample preservation. A comprehensive range of Simoa assay kits is available, delivering significantly enhanced sensitivity compared to traditional immunoassay methods. This ensures precise detection of biomarkers at both normal and acute levels across various sample types.

                  Ultra-sensitive Simoa® Bead Technology

                  Dectect multiplex analytes without compromising sensitivity or specificity

                  Semi-Automated

                  Simple 2-step or 3-step workflow with minimal user intervention

                  Convenient

                  Compact instrument with built-in touchscreen control and comprehensive data analysis tools

                  Flexible

                  Simple custom assay development for both protein and circulating nucleic acid detection

                  Low-maintenance

                  No daily or monthly user maintenance

                  Multiplex Measurement of Low-Abundance Circulating Proteins

                  The SR-X™ system enables multiplex detection of neurodegeneration biomarkers using the Simoa® bead-based assay. Healthy donor sample readings are presented alongside the lower limit of quantification (LLOQ), indicated by dashed lines, for each assay in its validated matrix.

                  Ready to Order?
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                  Quanterix Portfolio

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                  Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

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                    Evercode TCR Mega

                    PRODUCTS

                    Evercode TCR Mega

                    1M CELLS

                    96 SAMPLES

                    Unlock scalable immune profiling capabilities with Evercode™ TCR Mega, empowering you to analyze up to 1 million cells at a time. In the intricate landscape of immunity, comprehensive data is key. With Evercode™ TCR Mega, you can achieve unparalleled resolution in studying TCR clonotype diversity and T-cell states.

                    Benefit from the expansive scale of Evercode™ TCR Mega, which offers a host of advantages alongside the wealth of information provided by WT profiles. Whether you’re exploring immune responses, investigating cellular dynamics, or delving into immunotherapy research, Evercode™ TCR Mega equips you with the tools to navigate the complexities of the immune system with confidence and precision.

                    EXPONENTIALLY
                    SCALABLE

                    Evercode's combinatorial barcoding
                    enables you to dramatically
                    scale up the cells and samples per experiment.

                    NO INSTRUMENT
                    REQUIRED

                    If you have a centrifuge,
                    thermal cycler,
                    and some pipettes,
                    you’re ready to go.

                    UNMATCHED DATA QUALITY

                    Better detect lowly expressed
                    genes and avoid ambient RNA common
                    in droplet-based
                    single cell sequencing.

                    WORKS WITH FIXED CELLS AND NUCLEI

                    Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

                    Up to 1 million cells in a single experiment

                    Experience the power of scale with Evercode. Conduct experiments with up to 1 million cells in a single run, unlocking the immense diversity within the immune repertoire like never before. With Evercode, identify an extensive array of TCR clonotypes, providing unparalleled insights into immune function and response.

                    Not only can Evercode detect clonotypes, but it also offers the capability to map them to T cell subtype clusters. By analyzing gene expression profiles from nearly 1 million T cells isolated from PBMCs, Evercode enables the classification of cells into distinct T cell subtypes. This comprehensive approach ensures a deeper understanding of immune dynamics and facilitates more nuanced analysis of immune responses.

                    High TCR detection in activated and primary T cells

                    Experience outstanding TCR detection in both activated and primary T cells with our cutting-edge profiling techniques. In our investigation, T cells derived from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation through culture for 3 days with CD3/CD28 beads and IL-2 (Activated).

                    Our results demonstrate robust TCR detection in both experimental conditions, highlighting the versatility and reliability of our methodology across diverse T cell states. Whether profiling primary T cells or their activated counterparts, our approach ensures accurate and comprehensive characterization of the TCR repertoire, providing invaluable insights into immune responses and cellular dynamics.

                    Trust in our advanced profiling techniques to deliver precise and high-fidelity data, enabling a deeper understanding of T cell biology and immunological processes. With our innovative methodologies, delve into the complexities of the immune system with confidence and clarity, paving the way for transformative discoveries in immunology.

                    Comprehensive immune repertoire detection

                    Immerse yourself in unparalleled detection of the immune repertoire with the Evercode™ TCR kit, meticulously crafted to offer the most comprehensive profile attainable. In a groundbreaking study spanning 8 donors, our kit revealed the identification of nearly 500,000 unique beta chain clonotypes.

                    Notably, the majority of these clonotypes were deemed rare, emphasizing the remarkable sensitivity and depth of our detection capabilities. With the Evercode™ TCR kit at your disposal, you gain the ability to unveil the complete spectrum of immune diversity, from commonplace to exceptionally rare clonotypes. This empowers you to delve into the intricacies of immune responses with unparalleled precision and breadth, opening new avenues for exploration and discovery in immunology.

                    tcr parse workflow
                    Ready to Order?
                    Our team can help you in placing the order. Click below to get a quote and fast ordering.

                    Let’s Find You an Application That Helps Your Research

                    Get a call from your local Decode Science representative to help you find the best fit genomics products for you.

                      Or give us a call at:

                      1300 581 991