Entries by Harshita Sharma

Stratys

PRODUCTS

Stratys

Bionano Stratys Product

Elevate the OGM Sample-to-Report Workflow with the Stratys™ System

Embark on a revolutionary journey towards enhanced workflow speed and simplicity by leveraging the power of Optical Genome Mapping (OGM) combined with the cutting-edge Bionano Stratys™ System. With this innovative approach, break free from the limitations of conventional cytogenetics and sequencing techniques, as you delve into the comprehensive detection of all classes of structural variants. Experience a paradigm shift in genetic analysis, where efficiency and precision converge to unlock new realms of understanding within the genome.

500 bp

Detect SVs starting at
500 bp

5%

VAF at 5% or lower*

12 Samples

Scalable throughput

1200x

Up to 1200x target effective coverage

*Lower VAF percentages can be achieved when using the Stratys Plus Chip, which enables up to 1200x genome coverage.

Stratys Performance

STRATYS CHIPS

Experience unparalleled efficiency and tailored performance with STRATYS CHIPS – your gateway to optimized reagents and consumables for diverse applications. Tailor your journey to results with a versatile array of chips meticulously crafted to align with your unique requirements. Within the STRATYS chips, immerse DNA molecules in a precise nanofluidic environment, where they seamlessly linearize across hundreds of thousands of nanochannels. Through advanced imaging, unravel the intricate genomic architecture and uncover subtle structural variations with unparalleled clarity and accuracy.

STRATYS COMPUTE

Maximize workflow efficiency with STRATYS COMPUTE, your solution for streamlined data processing, ensuring a seamless flow of operations.

Data Processing Powerhouse: Powered by NVIDIA RTX GPUs, STRATYS COMPUTE boasts remarkable processing power, enabling significantly faster runtimes and reduced compute costs. Leveraging cutting-edge technology, software releases drive acceleration, enhancing overall performance.

Support a Constant Flow of Data: Benefit from STRATYS COMPUTE’s advanced technology and intelligent processing, facilitating a continuous stream of data from the Stratys instrument. This ensures optimal scalability of your workflow, maintaining productivity at scale.

Best Sensitivity for OGM: Equipped with the latest informatics pipeline for Optical Genome Mapping (OGM) data, STRATYS COMPUTE delivers unparalleled sensitivity for genome-wide detection of all classes of structural variants (SVs) using OGM technology.

Minimal IT Resources Required: Designed for ease of implementation, the STRATYS COMPUTE workstation can be conveniently installed alongside the Stratys instrument without the need for a dedicated data center. This reduces IT overhead and minimizes implementation time, ensuring a hassle-free setup process.

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Bionano Portfolio

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    Saphyr

    PRODUCTS

    Saphyr

    Saphyr System

    Reveal genome-wide structural variation with the Saphyr™ optical genome mapping system.

    Consistently identify structural variants across all classes with a resolution as low as 500 base pairs (bp) and a variant allele frequency (VAF) as low as 5% utilizing optical genome mapping (OGM) through the Saphyr™ system. Saphyr™ stands as the foremost tool for detecting structural variants, surpassing the capabilities of next-generation sequencing (NGS) methods and traditional cytogenetic approaches, thus capturing genomic variations often overlooked by these technologies.

    Achieve broad, unbiased genomic coverage with flexible data collection.

    The Saphyr™ system offers adaptable genomic coverage, enabling the identification of heterozygous or infrequent variants present in mosaic samples and heterogeneous tumors.

    In just six hours, obtain a comprehensive 100X coverage of a human genome. To uncover deeper and rarer variants, merely prolong the data collection time on Saphyr™ without incurring additional consumable costs. Achieve an impressive 400X coverage within a 24-hour period, facilitating structural variant (SV) detection down to a 5% variant allele frequency (VAF). Extend runtime further to explore variants with even lower VAF levels.

    Enjoy seamless integration and workflow efficiency with the Saphyr™ Chip® consumable and Saphyr™ system.

    The Saphyr Chips feature hundreds of thousands of highly parallel nanochannels, which efficiently linearize long, labeled DNA molecules, enabling direct imaging of your samples by the Saphyr instrument.

    Sample loading onto the Saphyr Chip is swift and straightforward. Easily pipette up to three samples into individual flow cells on the chip. With the capability to load up to two chips onto the Saphyr instrument per run, achieve a maximum throughput of six samples per operation.

    Benefit from the Saphyr instrument and chips’ integration of machine learning-based adaptive loading and automatic run optimization. These features ensure hassle-free scanning and optimize throughput speed, allowing for walk-away operation and the fastest achievable throughput for each run.

    Guarantee optimal performance through automated health system monitoring accessible remotely.

    The Saphyr™ Assure Service offers an optional (opt-in) automated health monitoring feature, which consistently evaluates data quality and instrument functionality. This feature detects potential issues before they impact data quality and performance, enabling Bionano Support to proactively address any concerns and conduct necessary repairs with minimal downtime.

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      Franklin

      PRODUCTS

      Franklin

      Introducing Franklin – a groundbreaking initiative that seamlessly integrates public data sets with real-world evidence, revolutionizing clinical diagnosis, expediting clinical reporting, ensuring consistent classification, all while fostering a thriving community of genomic professionals and upholding data sovereignty and security.

       



      Impacting Lives at the
      Point of Care



      Your Gateway to the
      Actionable Genome



      The Power of
      Community

      Actionable Insights: With Franklin, genomic professionals can redirect their focus from navigating evidence to delving into actionable insights. Our mission is to construct the most extensive and diverse real-world evidence dataset, unlocking answers to any genomic query through the collaborative power of the community, data, and insights.

      Franklin’s Community: Who makes up the Franklin community? Our genomic professionals hail from every facet of the medical genetics domain and span the globe. From genetic counselors, expert physicians, and oncologists to variant scientists, bioinformaticians, clinical geneticists, researchers, and pharmacologists, Franklin unites a diverse array of specialists dedicated to advancing genomic knowledge and practice.

      Franklin dashboard

      Want to try before you buy?

      Our team at Decode Science can help connect you with the experts at Genoox, to arrange a customised demo for your group.

      Let’s Find You an Application That Helps
      Your Research

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        DNBSEQ-E25

        PRODUCTS

        DNBSEQ-E25

        DNBSEQ-E25 : Sequence Your Samples On-The-Go

        Embark on a streamlined sequencing journey from sample to report with the DNBSEQ-E25 sequencer. This compact and standalone system is designed to operate effortlessly inside or outside the lab, providing versatility in its usage. The E25 seamlessly integrates a microfluidic chip, an integrated CMOS detection module, self-luminous dye, and a proprietary computing module. This harmonious combination results in a lightweight and cost-effective instrument that breaks free from location restrictions, allowing you to conduct sequencing processes with ease and efficiency. The DNBSEQ-E25 is your solution for convenient and accessible sequencing wherever you need it.

        Plug-and-Play

        This integrated sequencer is ideal for remote sites, providing ease-of-use and convenience.

        Efficient

        Quick and easy setup means you can start your run in just 10 minutes.

        Hassle-free

        No washing between runs streamlines your sequencing.

        Plug-And-Play

        Experience seamless and hassle-free sequencing with our plug-and-play solution. The DNBSEQ-E25 incorporates an integrated microfluidic sequencing chip with a CMOS detection module underneath each spot. This innovative design minimizes environmental sensitivity, reduces costs, and lightens the weight of the sequencer. The result is a truly plug-and-play system, streamlining the sequencing process and providing you with an efficient and user-friendly solution for your research needs.

        E25 Features with DecodeScience

        Data Analysis Has Never Been Easier

        Simplify your data analysis process with the DNBSEQ-E25, where efficiency meets ease. The advanced model, DNBSEQ-E25A, takes it a step further by incorporating an enhanced computing module capable of running data analysis for various applications, including whole-genome sequencing. These sequencing platforms operate as standalone systems, managing the entire workflow from sample to result without the need for a network connection. This not only ensures ease of use but also eliminates the risk of data breaches, providing you with a secure and reliable solution for your sequencing needs.

        E25 Data

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          DNBSEQ-G400

          PRODUCTS

          DNBSEQ-G400

          MGI G400

          DNBSEQ-G400 : Your Day-to-Day Sequencing Solution

          Elevate your day-to-day sequencing experience with the DNBSEQ-G400, your comprehensive sequencing solution. This system offers a versatile range of sequencing options, accommodating read lengths of up to SE400/PE300 and supporting two flow cell types. With built-in primary data analysis and optimized optical and biochemical systems, the DNBSEQ-G400 ensures a seamless and efficient sequencing process for your daily research needs. Trust in this innovative solution to deliver reliable and high-quality results, making it an essential tool for your routine sequencing endeavors.

          Accurate

          Our proprietary DNBSEQ technology ensures exceptional accuracy, eliminating clonal errors and index hopping-generating >99% SNP/indel precision and sensitivity.

          Versatile

          With a wide dynamic range (between 55 GB and 1440 GB per run per day) the G400 supports multiple read lengths, from SE50 up to SE400 or PE300.

          Flexible

          Choose between two flow cell types, depending on your throughput and runtime requirements. PE150 sequencing can be completed in as little as 37 hours.

          Features

          The sequencing platform offers a broad data output range of 55 Gb to 1440 Gb per run, with PE150(FCS) sequencing achieving full capacity in just 37 hours. It supports various read lengths, including SE50, SE100, SE400, PE100, PE150, PE200, and PE300. The platform’s versatility extends to diverse applications, encompassing basic research, clinical research, forensics, and agriculture, making it suitable for a wide range of scientific and investigative endeavors.

          DNBSEQ-G400

          Performance of G400 with DecodeScience

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            DNBSEQ-T7

            PRODUCTS

            DNBSEQ-T7

            DNBSEQ-T7 : Turbocharge your Sequencing

            Experience a sequencing revolution with the T7, designed to turbocharge efficiency across diverse projects such as whole genome, deep exome, epigenome, transcriptome, single-cell omics, spatial omics, and more. The T7 not only optimizes the entire sequencing process but also achieves extraordinary productivity. With the capability to generate a staggering 20,000 30x whole genomes in just one year, all at an affordable cost of $150 per genome, the T7 sets a new benchmark for high-quality data acquisition at an unparalleled speed. Embrace the future of genomics research with the T7, where efficiency meets affordability without compromising data quality.

            Flexible

            The T7 offers unmatched flexibility with its 4 independent flow cells, empowering you to run them at any time without the need to batch large quantities of samples

            Fast

            Achieve 24/7 production with your large sequencing project by generating 7 Tb data in 24 hours with automatic washes in between runs

            Accessible

            With a cost of $150 per Genome or $1.5/Gb, the T7 opens the doors to accessibility for your groundbreaking sequencing projects

            Say Goodbye to Amplification Errors Associated with PCR

            Bid farewell to amplification errors linked with PCR, as our cutting-edge technologies ensure precise and error-free amplification processes. With our advanced solutions, we prioritize accuracy and reliability, ensuring that your results are free from the concerns associated with amplification errors. Embrace a new era in PCR technology where precision and confidence in your data are paramount.

            T7Inside Workflow

            Independent Flow Cells

            Experience unparalleled flexibility in your sequencing workflows with the inclusion of 4 independent flow cells in our technology. These independent flow cells grant you the freedom to run sequencing processes at any time, eliminating the necessity to batch large quantities of samples. This innovative design empowers you to adapt your sequencing runs to specific requirements, offering enhanced efficiency and customization in your research endeavors.

            T7 Quad Cells

            Performane of T7 with DecodeScience

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              DNBSEQ-G99

              PRODUCTS

              DNBSEQ-G99

              G99 with DecodeScience

              DNBSEQ-G99 : The Ultimate in Sequencing Speed

              Introducing the DNBSEQ-G99, the epitome of sequencing speed and efficiency. This groundbreaking sequencer stands as the fastest ever created, offering unparalleled performance in low- to mid-range throughput, making it an exceptional choice for targeted gene and small genome sequencing research. The G99 features a triangular configuration on the patterned array, achieving a higher density of DNA Nanoballs (DNBs) and consequently yielding an impressive data output of up to 48 gigabytes per run.

              Equipped with a proprietary high-resolution objective lens and a high-precision temperature control system, the DNBSEQ-G99 sets a new standard for efficiency. With a remarkable run time for PE150 sequencing, completing the process within just 12 hours, this sequencer ensures swift and reliable results. Notably, during PE100 or PE150 sequencing runs, informative preliminary reports are available within the first 2.5 hours, providing researchers with rapid insights into their experiments. The DNBSEQ-G99 redefines sequencing capabilities, offering researchers an unprecedented combination of speed, density, and data output for accelerated and informative sequencing workflows.

              Fast

              Get up to 48 Gb (PE150 sequencing) in less than 12 hours.

              Flexible

              Run two independent flow cells at any time.

              Easy-to-Use

              Pre-loaded cartridges minimize human errors.

              Dual Flow Cells for Maximum Flexibility

              The DNBSEQ-G99 introduces a remarkable feature—dual flow cells for maximum flexibility. This innovative capability allows the sequencer to run two flow cells independently, providing users with the adaptable option to plug-and-play as needed. This dual-flow cell design enhances versatility and enables researchers to tailor their sequencing experiments to specific requirements, further expanding the utility and flexibility of the DNBSEQ-G99 in various applications.

              Dual Flow Cells for Maximum Flexibility G99

              Get up to 48 Gb per sequencing run

              Unlock unparalleled sequencing capabilities with the DNBSEQ-G99 and achieve up to 48 gigabytes of data per sequencing run. This impressive data output sets a new standard in sequencing efficiency, providing researchers with extensive genomic information in a single run. The DNBSEQ-G99 empowers users to generate large volumes of high-quality data, enabling comprehensive insights and accelerating advancements in genomics research.

              Performance of G99 with DecodeScience

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              MGI Portfolio

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                MGISP-7000

                PRODUCTS

                MGISP-7000

                MGISTP-7000 Features with DecodeScience

                MGISP-7000: Precision Meets Speedy Automation

                The MGISTP-7000 ushers in a new era of laboratory automation, meticulously designed to fulfill the requirements of high productivity without compromising safety or quality. This innovative system seamlessly integrates key functionalities, including barcode identification, tube decapping, automated liquid transfer, and negative pressure protection. By doing so, it establishes itself as a comprehensive and efficient sample preparation solution, streamlining processes and ensuring precision throughout the laboratory workflow.

                High Reliability

                Barcode data can be auto-transferred to other automation or LIMS for traceability

                Safe

                Two HEPA filters and UV light enhance safety for liquid transfers and lab technicians

                Automated

                Load sample tubes in a standard rack with one click to automate pre-analysis steps

                High-Throughput Automated Nucleic Acid Extraction Platform

                The MGISTP-7000 stands as a groundbreaking advancement in laboratory automation, specifically revolutionizing sample transfer and nucleic acid detection processes. Noteworthy for its unwavering commitment to safety, the system incorporates dual HEPA filters and an integrated UV light, creating and maintaining a pristine, contamination-free environment. The ISO5 air filter captures an impressive 99.995% of particles at 0.3um, complemented by a specialized venting mechanism efficiently removing potentially contaminated air from the lab space.

                In terms of user experience, the MGISTP-7000’s software is designed with a strong emphasis on user-centricity. With a single click, it automates pre-analytical steps, showcasing both efficiency and user-friendly operation. The robust mechanics of the system can transfer 192 samples to 96-Well Microplates in just 40 minutes, further contributing to its powerful and efficient performance.

                On the connectivity front, the MGISTP-7000 stands out for its compatibility with ZLIMS, allowing for seamless integration with third-party analytical instruments. This adaptability ensures its compatibility with the evolving needs of laboratory workflows.

                Selecting the MGISTP-7000 guarantees a harmonious blend of efficiency, safety, and advanced capabilities in your lab workflows, representing a significant step forward in high-throughput automated nucleic acid extraction platforms.

                About MGISTP-7000 with DecodeScience

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                  MGISP-3000

                  PRODUCTS

                  MGISP-3000

                  MGISP-3000 with DecodeScience

                  MGISP-3000: Unmatched Speed, Unrivaled Safety

                  MGISP-3000 establishes a new benchmark in laboratory automation, harmonizing high-throughput efficiency with unmatched safety measures. Boasting features such as ISO5 air filtration, one-click sample pre-analysis, and seamless ZLIMS integration, it provides a comprehensive and secure solution for modern lab workflows.

                  High Reliability

                  Barcode data can be auto-transferred to other automation or LIMS for traceability

                  Safe

                  Two HEPA filters and UV light enhance safety for liquid transfers and lab technicians

                  Automated

                  Load sample tubes in a standard rack with one click to automate pre-analysis steps

                  MGISP-3000: Elevating Lab Automation and Safety Standards

                   

                  The MGISP-3000 stands as a pinnacle in lab automation, seamlessly blending high-throughput efficiency with a paramount focus on safety. With features such as ISO5 air filters and external exhaust, it creates an ultra-clean workspace, ensuring a secure environment for various lab tasks.

                  Its user-friendly design simplifies operations with a single-click automation of pre-analysis steps, guaranteeing a swift and error-free experience through an intuitive interface. This innovation not only prioritizes safety but also enhances the overall efficiency of laboratory workflows.

                  The MGISP-3000 is future-ready, demonstrating seamless integration capabilities with ZLIMS and third-party systems like RT-PCR. This adaptability makes it a versatile solution for evolving lab requirements, ensuring it stays in sync with the latest advancements in the field.

                  Moreover, MGISP-3000 goes beyond the conventional by combining top-notch safety measures, streamlined operations, and scalability. It introduces features such as barcode tracking and automated tube sealing, providing a comprehensive solution that meets the demands of high throughput without compromising quality.

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                    MGISP-100

                    PRODUCTS

                    MGISP-100

                    MGISP-100 With DecodeScience

                    MGISP-100 : Precision Prep, Peak Performance

                    Introducing MGISP-100, an advanced automated workstation featuring an 8-channel pipette, specifically designed for sequencing library preparation. This state-of-the-art system excels in processing samples in bulk, guaranteeing both stability and cost-effectiveness to elevate lab productivity. Tailored to meet user requirements, MGISP-100 comes equipped with a range of integrated tools, including PCR machines, UV lamps, and temperature modules. It promotes hands-free, precise, and streamlined operations, ensuring efficient and reliable sequencing library preparation processes.

                    Open Platform

                    Tailored development crafted to meet specific and unique requirements

                    Comprehensive Protection

                    Equipped with a UV lamp and laminar flow hood for a thorough contamination prevention approach

                    Comprehensive Functions

                    Incorporates essential functional modules such as the PCR machine, magnetic rack, temperature modules

                    Economic & Efficient

                    Fully autonomous system, processes samples in bulk, significantly minimising the need for manual intervention

                    The MGISP-100 stands as an advanced automated workstation

                    The MGISP-100 represents a pinnacle in automated workstations, skillfully designed with an 8-channel pipette to facilitate seamless sequencing library preparations. Its batch processing capability ensures uniform outputs, optimizing operational expenses and elevating laboratory efficiency. In addition to its core features, the MGISP-100 is equipped with a suite of integrated tools, including PCR machines, UV lamps, and precise temperature modules, ensuring a meticulous and autonomous operational experience.

                    The versatile capabilities of MGISP-100 extend across various stages of the laboratory workflow, encompassing nucleic acid extraction, enzymatic reactions, size selection, DNB making, magnetic beads purification, PCR, target capture, and incorporating a HEPA system for enhanced contamination control.

                    MGISP-100 Workflow and Features

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