Sequencing Platforms Archives

DNBSEQ T7+

October 22, 2025/in MGI, Partners, Sequencing Platforms/by Harshita Sharma

T7+: Ultra-Fast, High-Throughput Sequencing Without Compromise

T7+ is an integrated ultra-high-throughput sequencing platform built for labs that demand speed, accuracy, and scale. Leveraging MGI’s DNBSEQ™ Technology and SM2.0 biochemistry, it delivers over 14Tb of high-quality sequencing data in 24 hours, making large-scale genomics projects—from population studies to clinical pipelines—both feasible and efficient. Its 7-in-1 modular design automates the entire workflow, reducing hands-on time and minimizing potential errors.

Beyond sheer performance, T7+ is engineered with clinical relevance in mind. Its capacity for up to 35,000 whole-genome sequences annually ensures that your lab can meet high-throughput demands without compromising turnaround times. This efficiency directly translates to faster research insights, improved diagnostic workflows, and smoother integration into daily lab operations, helping you focus on what matters most: accurate, actionable genomic data.

>14 Tb/24h ultra-fast sequencing

7-in-1 automation: prep to analysis

QUAD-Flow Cells: PE150 & PE100 simultaneous

Q40 >90% high-quality output

Ergonomic & modular design

Smart system with diagnostics & self-healing

Omni-smart hub guides workflows

Checkpoint resume for uninterrupted runs

Learn more about how each feature works as you scroll.

Watch How T7+ Works

Why It Matters?

Every hour matters when precision, speed, and reliability determine outcomes. T7+ addresses these challenges by combining ultra-high throughput, rapid turnaround, and intelligent automation, so you can focus on results rather than processes.

Get a complete overview of T7+ performance, throughput, workflow automation, and configuration options. For guidance on integrating T7+ into your operations, Decode Science can provide personalized support and local assistance.

Download T7 Plus Brochure

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DNBSEQ T7+

DNBSEQ-T1+

DNBSEQ-E25

DNBSEQ-G400

DNBSEQ-T7

DNBSEQ-G99

DNBSEQ-T1+

October 8, 2025/in MGI, Partners, Sequencing Platforms/by Harshita Sharma

Accelerate high-throughput genomic testing with DNBSEQ-T1+

The DNBSEQ-T1+ is one of the fastest T-level benchtop sequencers available globally—built on MGI’s proven DNBSEQ™ technology for accuracy, scalability, and reliability. Designed for clinical and translational genomics labs, the T1+ supports dual flow cell operation, delivering up to 1.2 terabases (Tb) of sequencing data within 24 hours (600 Gb per flow cell).

For laboratories managing time-sensitive or high-volume projects, this means faster turnaround, improved workflow efficiency, and reduced dependence on external bioinformatics infrastructure. The optional integrated bioinformatics module enables automated secondary analysis immediately after sequencing, helping clinicians and molecular pathologists move from raw data to interpretable results without delay.

In practice, DNBSEQ-T1+ helps streamline comprehensive genomic profiling (CGP), oncology testing, and clinical research pipelines—supporting both diagnostic accuracy and operational consistency across runs.

High-Speed, High-Throughput Sequencing

Generate up to 1.2 Tb of data in a single run with dual flow cell operation.

Choose from FCL, FCM, or FCS flow cells to match your throughput needs—from small clinical batches to large oncology cohorts.

Maintain >93% Q30 and >90% Q40 base quality across read lengths up to PE150.

Complete full runs in as little as 7–24 hours, supporting faster reporting and clinical turnaround.

Versatile Applications Across Clinical Genomics

Flexible read lengths (SE50–PE300) suit NIPT, RNA-Seq, oncology panels, WES, WGS, and methylation studies.

Supports coverage depth from 1 Gb to 120 Gb per sample, enabling both targeted assays and whole-genome workflows.

Ideal for translational and precision medicine—from pathogen detection to tumour profiling.

Integrated DNB Make & Load Technology

DNB M&L (Make & Load) module automates DNB preparation and loading directly within the sequencer.

Delivers consistent, contamination-free results with minimal hands-on time.

Each flow cell operates independently, supporting different read lengths or applications in parallel.

Enables an end-to-end “Make–Sequence–Analyse” workflow that saves time and reduces error.

Smart Configurations and Automated Analysis

Available in two setups: DNBSEQ-T1+ RS (flexible throughput) and T1+ ARS (with built-in bioinformatics).

The ARS configuration automatically triggers advanced data analysis post-run, streamlining bioinformatics pipelines.

Simplifies data interpretation for clinicians and molecular pathologists, improving workflow efficiency and diagnostic accuracy.

Download the DNBSEQ-T1+ brochure for a complete overview of performance metrics, application data, and configuration options. For guidance on how this platform fits your lab’s workflow, Decode Science can walk you through integration and local support options.

Watch How T1+ Works

DNBSEQ-E25

January 29, 2024/in MGI, Partners, Sequencing Platforms/by Harshita Sharma

E25: Sequencing on the Go

Not every sequencing question belongs in a core facility. Whether you’re working at a remote field site, a resource-limited clinic, a teaching lab, or simply need a dedicated benchtop instrument without competing for shared equipment time, the DNBSEQ-E25 puts high-quality sequencing where you need it. Weighing just 15 kg and requiring nothing more than a power source, the E25 integrates microfluidic flow cell technology, CMOS-based detection, and self-luminous dye chemistry into a single compact unit that takes you from loaded sample to FASTQ output — no ancillary hardware, no bioinformatics workstation, no internet connection.

What sets the E25 apart from other portable or benchtop sequencers is the degree to which the entire workflow is self-contained. The built-in computing module handles base calling and report generation on-board, and the enhanced E25A model extends this to full data analysis pipelines for applications including whole-genome sequencing. There’s no washing required between runs, setup takes roughly 10 minutes, and the system supports both MGI and App-C libraries without primer substitutio

But... Why E25?

Specifications

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Supports MGI and App-C libraries and requires no primer substitutions
Reads*	Read Length**	Data Output	Run Time***	Q30****
25 M	SE100	2.5 Gb	5 hrs	>90%
25 M	PE150	7.5 Gb	20 hrs	>80%
* The maximum number of valid reads is obtained by running a specific standard library. Actual performance may vary depending on sample type and library construction method. SE100 consumables can be used for SE50 sequencing; PE150 consumables can be used for PE100 sequencing. Read lengths can be customized in the sequencer user interface. * Run time includes DNB loading and FASTQ generation. Barcode sequencing time is excluded. **** Q30 and run time are averaged across the entire run using a standard library. Actual performance may vary depending on sample type, library quality, insert size, etc.

Product Model

E25, E25A*

Power, Dimensions & Net Weight

Rated Power: 25V DC, 5A
Dimensions (L×W×H): 348 mm × 312 mm × 257 mm
Net Weight: 15 kg

Operating Environment Requirements

Temperature: 15℃–30℃
Relative Humidity: 20% RH – 80% RH
Atmospheric Pressure: 70 kPa – 106 kPa
Pollution Level: Level 2

* For indoor use only.

Why It Matters to You

How You Can Achieve These Results

Considering portable sequencing for your lab or field site?

We can advise on applications, library compatibility, and how the E25 fits into your current workflow. Simply reach out to me.

What our customer says...

Dr Lyman Ngiam (PhD)

Postdoctoral Research Fellow at Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance

"Both E25 and D4 have demonstrated the capability to generate sequencing results within a single day. The prebuilt library preparation protocol and streamlined sequencing workflow make the system highly user-friendly, enabling anyone with piptetting skill to perform sequencing runs with ease. The simplified operation has significantly reduced preparation time. Notably, the system’s ability to work with low starting DNA concentrations makes it particularly versatile, allowing sequencing of a wide range of sample matrices without the need to obtain high DNA yields beforehand. Overall, it is an efficient and practical platform, essentially a "load-and-go" system."

MGI Portfolio

DNBSEQ T7+

DNBSEQ-T1+

DNBSEQ-E25

DNBSEQ-G400

DNBSEQ-T7

DNBSEQ-G99

DNBSEQ-G400

January 29, 2024/in MGI, Partners, Sequencing Platforms/by Harshita Sharma

G400: Seamless, Fast, and Precise Sequencing

Most genomics labs don’t run one application — they run many. The DNBSEQ-G400 is designed for exactly this reality. With two independent flow cell slots, two flow cell formats (FCS and FCL), and read configurations spanning SE50 through to PE200 and even SE400, the G400 lets you run different applications simultaneously on the same instrument without compromising on turnaround or data quality. Powered by MGI’s StandardMPS 2.0 reagent chemistry, the platform achieves Q40 accuracy across key read lengths — a level of base-calling precision that reduces error rates and strengthens confidence in variant calls, differential expression, and any downstream analysis where per-base accuracy matters.

What makes the G400 particularly practical for mid-scale genomics operations is the balance between throughput and flexibility. The large flow cell (FCL) delivers up to 1,800M reads and 540 Gb per flow cell at PE150, putting whole-genome sequencing, large RNA-seq experiments, and high-depth exome batches comfortably within reach. Meanwhile, the small flow cell (FCS) supports faster, lower-volume runs — ideal for targeted panels, amplicon sequencing, or urgent turnaround samples — without wasting capacity.

Flexible Enough for Every Application on Your List

Running multiple sequencing applications and need a single platform that handles them all? Our team can walk you through flow cell configurations, throughput planning, and how the G400 fits alongside your existing setup.

Why It Matters to You

For Genomics Core Facilities

Your users submit everything from targeted panels to whole genomes, and they all want results yesterday. The G400’s dual flow cell design lets you batch high-throughput projects on the FCL while running urgent or low-volume jobs on the FCS — simultaneously. Q40 data quality across key read lengths means fewer reruns and higher first-pass success rates, keeping your queue moving and your users satisfied.

For Cancer & Clinical Research Labs

Somatic variant detection demands accuracy. Q40-grade base quality reduces false positive variant calls, particularly at low allele frequencies where sequencing errors and true variants are hardest to distinguish. The G400’s flexible read lengths also let you run tumour-normal WGS, RNA-seq for gene expression, and targeted hotspot panels on a single platform — simplifying your instrument fleet and standardising your data quality.

For Translational & Pharma Research Groups

Drug target validation, biomarker discovery, and companion diagnostic development all require reproducible, high-quality sequencing data across multiple assay types. The G400 supports the breadth of applications these programmes demand — WGS, WES, RNA-seq, methylation, targeted panels — on a single instrument with consistent Q40 performance, reducing the platform-to-platform variability that complicates cross-study comparisons.

For Agricultural & Environmental Genomics

Genotyping-by-sequencing, amplicon panels for pathogen surveillance, metagenomic profiling, and small genome assemblies all fit comfortably within the G400’s output range. The SE400 read mode is particularly relevant for applications requiring longer contiguous reads without moving to a long-read platform. For labs processing high sample volumes across diverse project types, the dual flow cell system keeps throughput high while accommodating varied experimental designs.

Specifications & resources

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Performance by Read Length
Read Length	Data Output/Flow Cell	Data Quality Q30*	Data Quality Q40*	Run Time**
SE50-FCL	75 Gb ~ 90 Gb	>90%	>85%	~14 h
SE100-FCL	150 Gb ~ 180 Gb	>90%	>85%	~25 h
SE400-FCL	600 Gb ~ 720 Gb	>70%	/	~109 h
PE100-FCL	300 Gb ~ 360 Gb	>85%	>85%	~35 h / 38 h***
PE150-FCL	450 Gb ~ 540 Gb	>85%	>85%	~50 h / 56 h***
PE200-FCL	600 Gb ~ 720 Gb	>75%	/	~107 h
SE100-FCS	55 Gb	>85%	/	~13 h
PE100-FCS	110 Gb	>85%	/	~22 h / 26 h***
PE150-FCS	165 Gb	>85%	/	~31 h / 37 h***
* The percentage of bases above Q30 and Q40 is the average from internal standard libraries across the full run. Actual results may vary depending on sample type, library quality, and insert fragment length. Q40 is only achievable with StandardMPS 2.0 reagents.
** Run time is calculated based on dual-slide mode and includes sample loading, sequencing, base calling, and data processing.
*** 35 h, 50 h, 22 h, and 31 h reflect reduced times with the latest system upgrade.

MGI Portfolio

MGISTP-B1000

MGISP-7000

MGISP-3000

MGISP-100

MGISP-NE32

MGIFLP-L50

MGISP-960

MGISP-NEX

MGISP-NE384

MGISP-Smart 8

DNBSEQ-T7

January 29, 2024/in MGI, Partners, Sequencing Platforms/by Harshita Sharma

Turbocharge Your Sequencing with MGI DNBSEQ-T7

High-throughput sequencing projects often stall when data volume, turnaround time, or workflow scalability become limiting factors — especially in whole genome, deep exome, transcriptome, and epigenome studies. Traditional platforms struggle to keep pace, leading to longer runtimes, bottlenecks between runs, and delayed analysis.

DNBSEQ-T7 solves this by delivering ultra-high-throughput sequencing designed specifically for data-intensive genomics.
Built on DNBSEQ™ Technology, it combines advanced biochemical, fluidic, and optical systems to generate up to 6 terabytes of high-quality sequencing data per day, enabling faster completion of large and parallel sequencing projects.

Designed for population-scale studies and production sequencing, DNBSEQ-T7 allows labs to run multiple workflows simultaneously without compromising data quality or consistency. It fits seamlessly into large genomics programs where speed, scale, and sustained performance are critical.

For genomics core facilities and research institutes running high-volume sequencing operations, DNBSEQ-T7 removes throughput constraints and accelerates time to results—without forcing workflow trade-offs.

But... Why T7?

SPECIFICATIONS

Dimensions & Weight

Dimensions (L × W × H): 1656 mm × 903 mm × 1815 mm
Net Weight: 765 kg

Power

Power Type: 200 V~240 V, 50/60 Hz, 30 A
Rated Power: 3000 VA

Floor Bearing Capacity

Over 650 kg/m²

Operational Environment Requirements

Temperature: 19°C~25°C; fluctuation < 2°C per hour
Relative Humidity: 30% RH ~ 80% RH; non-condensing
Atmospheric Pressure: 80 kPa ~ 106 kPa
Waterproof Rating: IPX0
Altitude: Below 2000 meters

Bandwidth for Network Connection

300 Mb/s: For local storage network uploads

Number of Flow Cells : 1-4

Reads : 5800 M

Read Length

PE100:
1. Data Output: 1 – 4 Tb
2. Run Time: 20 – 22 hr
3. Q30: >85%
PE150:
1. Data Output: 1.5 – 6 Tb
2. Run Time: 24 – 30 hr
3. Q30: >85%

The maximum number of effective reads is based on the sequencing of an internal standard library. Actual output may vary with sample types and library preparation methods.

Run time includes DNB loading, sequencing, and base calling. The percentage of base above Q30 is the average of an internal standard library over the entire run. The actual performance is affected by factors such as sample type, library quality, and insert fragment length.

The DNBSEQ sequencing platforms are for Research Use Only. Not for use in diagnostic procedures.

DNBSEQ-T7 (CE-IVD)

Product Code: 900-000241-00

DNBSEQ-T7RS

Product Code: 900-000242-00

For guidance on integrating T7 into your research, Decode Science can provide personalised support and local assistance. Simply reach out to me.

RESOURCES

Download DNBSEQ-T7 Brochure For More Details

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MGI Portfolio

DNBSEQ T7+

DNBSEQ-T1+

DNBSEQ-E25

DNBSEQ-G400

DNBSEQ-T7

DNBSEQ-G99

January 29, 2024/in MGI, Partners, Sequencing Platforms/by Harshita Sharma

G99: Lightning-Fast, High-Precision

Speed matters in genomics — and not just for urgent clinical samples. Faster turnaround means tighter experimental iteration, shorter time-to-answer for surveillance workflows, and more efficient use of lab time across every application. The DNBSEQ-G99 is engineered around this principle. Delivering PE150 sequencing with Q40 base quality in approximately 12 hours, it is one of the fastest benchtop sequencers in its throughput class. That speed comes from coordinated advances in biochemistry, optics, fluidics, and temperature control — not from cutting corners on data quality. Q40 accuracy (fewer than 1 in 10,000 miscalled bases) is maintained across key read lengths using MGI’s StandardMPS 2.0 reagents, giving you high-confidence data on the first pass.

What gives the G99 its breadth is the three-tier flow cell system. The FCS (40M reads) handles small targeted panels and rapid-turnaround jobs. The FCL (80M reads) covers the mid-range — oncology panels, microbial genomes, RNA-seq, methylation, and more — with read lengths from SE50 through PE300 and even SE400 for forensics and long-amplicon work. And the FCU (200M reads) extends into whole-exome sequencing territory, delivering up to 120 Gb per flow cell at PE150 and supporting batches of 8 or more exomes per run. With dual flow cell slots running independently, you can pair any two of these formats in a single run — matching throughput to demand without wasting capacity or waiting for a full batch.

Q40 Accuracy in 12 Hours — The Benchtop Sequencer Built for Speed, Flexibility, and Clinical-Grade Data

Need help matching flow cell format and read length to your application? Our sequencing specialists can model your sample batching, per-sample costs, and turnaround times — reach out and we’ll respond at the earliest.

Specifications

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For guidance on integrating T7 into your research, Decode Science can provide personalised support and local assistance. Simply reach out to me.

Why It Matters to You

For Clinical & Diagnostic Genomics Labs

Turnaround time is a clinical deliverable, not a convenience metric. PE150 in 12 hours with Q40 accuracy means panels and exomes can be reported within clinically relevant timeframes. The G99's App-D compatibility with Illumina libraries simplifies validation and transition for labs moving from existing platforms, and the optional bioinformatics module (G99A) enables on-board analysis without external compute infrastructure — reducing IT overhead and data security complexity.

For Oncology Panel & Precision Medicine Groups

Somatic variant calling at low allele frequencies demands both accuracy and depth. Q40 data quality reduces false positive calls that waste follow-up resources, while the G99's flexible batching — from a handful of samples on the FCS to larger cohorts on the FCU — means you're not over-sequencing small batches or under-powering large ones. Methylation-based cancer detection panels are equally well served, with PE150 support at the depths these assays require.

For Infectious Disease & Public Health Surveillance

Pathogen identification, resistance profiling, metagenomic screening, and 16S community analysis all run on the G99. SE50 and SE100 modes handle rapid pathogen detection with same-day turnaround. PE300 on the FCL or FCU supports full 16S sequencing for microbiome and environmental monitoring. ATOPlex respiratory and COVID-19 panel workflows are directly supported, and the dual flow cell system lets you run surveillance samples alongside research projects without scheduling conflicts.

Our team is ready to guide you through solutions that match your lab or clinical needs.

>14 Tb/24h ultra-fast sequencing

7-in-1 automation: prep to analysis

QUAD-Flow Cells: PE150 & PE100 simultaneous

Q40 >90% high-quality output

Ergonomic & modular design

Smart system with diagnostics & self-healing

Omni-smart hub guides workflows

Checkpoint resume for uninterrupted runs

Ultra-Fast Sequencing:

Seamless Automation:

Chris Wicky

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Smart & Intuitive Operation:

Reliable Data Management:

Versatility for Multi-Omics:

High-Speed, High-Throughput Sequencing

Versatile Applications Across Clinical Genomics

Integrated DNB Make & Load Technology

Smart Configurations and Automated Analysis

Chris Wicky

Truly Portable Sequencing

Integrated Detection, No Optical System Required

Sample to Report — No External Computing

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Product Model

Power, Dimensions & Net Weight

Operating Environment Requirements

Ebru Boslem

What our customer says...

Contact Decode Science Today

Q40 Data Quality as Standard

Dual Flow Cell, Dual Application Flexibility

C. Read Length Versatility from SE50 to SE400

D. Production-Ready Throughput in a Manageable Footprint

Chris Wicky

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Reads Per Run

Samples

Read Lengths

DNBSEQ-T7 (CE-IVD)

DNBSEQ-T7RS

Ebru Boslem

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Contact Decode Science Today

PE150 at Q40 in 12 Hours

Three Flow Cell Formats, One Instrument

Read Lengths from SE50 to SE400 — Including PE300

Chris Wicky

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Ebru Boslem

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