Evercode WT Mini

February 20, 2024/in Evercode, Parse, Partners/by Harshita Sharma

PRODUCTS

Evercode WT Mini

Introducing Evercode™ WT Mini V2, the revolutionary solution for single-cell whole transcriptome analysis. Designed to operate without the need for additional instruments, the Evercode™ WT Mini V2 allows you to delve into single-cell transcriptomics with ease and convenience.

Key features include:

Compact Design: The Evercode™ WT Mini V2 is perfectly sized for researchers looking to explore single-cell transcriptomics on a smaller scale. Its compact design makes it ideal for generating proof-of-concept results before scaling up to larger platforms.
Quality Results: Experience the exceptional quality of results achievable with Parse technology. The Evercode™ WT Mini V2 enables you to obtain reliable and accurate transcriptomic data from individual cells, providing valuable insights into your biological samples.
Scalability: As your research progresses, seamlessly transition to larger platforms such as the Evercode™ WT or Evercode™ WT Mega to delve deeper into your biology. The Evercode™ WT Mini V2 serves as an ideal starting point for expanding your single-cell transcriptomics studies.

With Evercode™ WT Mini V2, unlock the potential of single-cell transcriptomics and embark on a journey of discovery in your research. Explore the complexities of gene expression at the single-cell level and uncover new insights into cellular heterogeneity and biological processes.

Higher Sensitivity with Evercode WT v2

Experience unmatched sensitivity in gene detection with Evercode WT v2. In a comparative study conducted in mouse brain samples, Evercode WT v2 outperformed the Chromium Next GEM Single Cell 3’ Kit v3.1, detecting an average of 84% more genes at a common read depth target of 20,000 reads per cell.

With Evercode WT v2, you can uncover a broader spectrum of genes and gain deeper insights into gene expression profiles, providing invaluable information for your research endeavors. Elevate your single-cell transcriptomics studies to new heights with the superior sensitivity of Evercode WT v2

Lower multiplet rates than droplet-based approaches

Achieve significantly lower multiplet rates compared to droplet-based approaches with Evercode WT. In a human-mouse species mixing experiment utilizing Evercode WT, we observed an impressively low multiplet rate of only 2.3%. This rate is substantially lower than what is typically encountered with droplet-based methods.

By leveraging Evercode WT, researchers can confidently minimize the occurrence of multiplets, ensuring greater accuracy and reliability in single-cell transcriptomic analysis. This enhanced precision allows for more accurate interpretation of biological data and deeper insights into complex biological systems.

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OGM Data Services

February 19, 2024/in Bionano, Partners/by Harshita Sharma

PRODUCTS

OGM Data Services

USING OGM IN YOUR RESEARCH

Incorporating Optical Genome Mapping (OGM) into your research opens up a realm of possibilities for detecting genome-wide structural variations with unparalleled sensitivity and unbiased analysis. Unlike sequencing-based technologies and conventional cytogenetic techniques, OGM offers a comprehensive and highly sensitive approach to uncovering structural variations within the genome.

By leveraging our services laboratory, you can embark on projects to analyze samples using OGM. Our expert team will guide you through the process, ensuring accurate and reliable results. Whether you’re exploring genetic anomalies in cancer, investigating constitutional genetic disorders, or studying complex genomic rearrangements, OGM provides a powerful tool for uncovering structural variations with precision and efficiency.

With OGM, you can gain deeper insights into the genomic landscape of your samples, leading to breakthroughs in understanding disease mechanisms, identifying potential therapeutic targets, and advancing personalized medicine initiatives. Join us in harnessing the transformative potential of OGM to drive forward your research and uncover the hidden secrets of the genome.

HOW IT WORKS

During an Optical Genome Mapping (OGM) research project with our services laboratory, you’ll embark on a collaborative journey with our experienced team.

Here’s how it works:

Project Initiation: You’ll collaborate with our team to define the scope of your research project. Together, we’ll discuss your research question, objectives, and sample set selection.
Sample Analysis: Once the project scope is defined, our laboratory will perform OGM and initial structural variant analysis on your selected sample set. Using state-of-the-art technology and methodologies, we’ll generate high-quality data to address your research needs.
Collaboration and Communication: Throughout the project, we’ll maintain open communication channels to ensure that your research goals are met. We’ll provide regular updates on the progress of the analysis and seek your input as needed.
Data Delivery: At the conclusion of the project, you’ll receive comprehensive deliverables, including raw molecules data, assemblies, and annotated structural variant (SV) calls. Additionally, we’ll provide training on our proprietary visualization software, empowering you to explore and interpret the results effectively.
Data Integration: Our team will support you in integrating OGM results with other data types, such as sequencing and array data. We’ll facilitate exports to various file formats, including VCF files, enabling seamless comparison and combination of OGM results with other datasets.

Through this collaborative approach, we aim to deliver actionable insights that advance your research objectives and drive scientific discovery. Join us in unlocking the full potential of OGM to uncover the mysteries of the genome and accelerate breakthroughs in your field of study.

COMPARISON ANALYSIS

Structural variants called against GRCh37/hg19 or GRCh38/hg38 will be filtered against a control database or gene list of choice based on the project goals. Dual or trio variant annotation can be run for various applications. These include identifying de novo or inherited variants in germline samples, somatic variants in matched tumor-control samples, and targeted structural variants in edited versus unedited control cell lines. Just indicate the relationship between samples in the intake form.

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Bionano Portfolio

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Compute Solutions

February 19, 2024/in Bionano, Partners/by Harshita Sharma

PRODUCTS

Compute Solutions

Experience comprehensive solutions for Optical Genome Mapping (OGM) data management and processing with Bionano Compute. Our suite encompasses a full spectrum of hardware, software, and cloud-based solutions, ensuring a seamless workflow from start to finish.

Bionano Compute offers end-to-end experiment management and bioinformatics processing, empowering researchers with robust tools for efficient data analysis. Additionally, it provides convenient management and monitoring tools tailored for the Saphyr™ and Stratys™ instruments, streamlining operations and enhancing productivity.

With Bionano Compute, researchers can harness the power of advanced technology to unlock insights from genomic data with unparalleled ease and efficiency.

The Stratys™ Compute high-performance workstation ensures seamless scalability for your workflow demands.

Fueled by NVIDIA RTX GPUs, it offers expedited runtimes and reduced compute costs, thanks to its cutting-edge technology. With each software release, expect accelerated performance, enhancing overall efficiency.

Experience unparalleled sensitivity in detecting all classes of structural variants (SVs) across the genome with the latest informatics pipeline tailored for Optical Genome Mapping (OGM) data.

Installed alongside the Stratys instrument, the Stratys Compute workstation minimizes IT burdens and implementation time, optimizing your setup for streamlined operations.

Reduce infrastructure costs and expand your Optical Genome Mapping (OGM) capacity effortlessly with Bionano Compute On Demand.

This pay-per-use solution, accessible via the Bionano Access web server for Bionano Solve operations, revolutionizes OGM data analysis from the Saphyr™ or Stratys™ instruments without necessitating additional infrastructure. Enjoy the flexibility and scalability your experiments demand with Compute On Demand.

Key advantages of Compute On Demand include:

Analyze large genomes and numerous samples simultaneously, maximizing throughput and efficiency.
Perform pipeline analysis operations seamlessly, without concerns about server capacity constraints.
Safeguard data integrity with encryption measures, ensuring secure operations and compliance with data protection regulations.
Maintain data center compliance with IPAA, CSA, SOC2, and ITAR regulations, guaranteeing adherence to industry standards and regulations.

With Bionano Compute On Demand, unlock the full potential of your OGM experiments while optimizing costs and maintaining data security and compliance.

Experience high-speed, on-site Optical Genome Mapping (OGM) data processing tailored for the Saphyr™ with the Saphyr™ Compute Server.

This compact solution delivers cluster-like performance at an affordable cost, revolutionizing your data analysis capabilities.

Key features of the Saphyr™ Compute Server include:

Cluster-like Performance: Enjoy the power of multiple simultaneous analyses and sustained throughput, reducing downtime and accelerating your research.
Rapid Analysis: Perform rare variant analysis and annotation of a human genome in approximately nine hours, enabling swift insights into complex genomic structures.
User-Friendly Interface: Seamlessly integrate the Saphyr™ Compute Server into any network setup with its simple web-based interface, ensuring compatibility and ease of use.

With the Saphyr™ Compute Server, spend less time waiting for data and more time delving into meaningful results, advancing your research endeavors with unparalleled efficiency and speed.

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Sample Preparation Kits

February 19, 2024/in Bionano, Partners/by Harshita Sharma

PRODUCTS

Sample Preparation Kits

Effortlessly prepare samples for Optical Genome Mapping (OGM) with Bionano’s comprehensive Sample Preparation Solutions, ensuring accurate identification of structural variants.

OGM necessitates labeled ultra-high molecular weight (UHMW) DNA, and Bionano offers a diverse range of DNA sample prep kits designed for simple and reliable isolation of UHMW DNA from various sample types. Once DNA isolation is complete, our Direct Label and Stain (DLS) kits can efficiently label DNA for compatibility with the Saphyr system.

With our Generation 2 Kits, featuring robust enhancements and optimizations to the sample preparation OGM workflow, you can achieve sample-to-answer results in just 3 to 4 days! Experience accelerated and streamlined sample preparation, paving the way for enhanced genomic analysis and structural variant detection.

Attain robust isolation and labeling of Ultra-High Molecular Weight (UHMW) DNA, crucial for visualizing large genomic structural variants.

Bionano’s innovative Solution Phase (SP) technology facilitates the isolation of DNA fragments exceeding 1 Megabase pair (Mbp) in length, consistently yielding average fragments surpassing 230 kilobase pairs (kbp).

To contextualize, while short-read sequencing generates reads up to 150 base pairs (bp) in length, even leading high-accuracy long-read sequencing methods offer read lengths limited to approximately 25 kilobases (kb). Bionano’s SP technology surpasses these limitations, enabling the analysis of genomic structural variants with unprecedented detail and accuracy.

Extract DNA from a diverse array of crucial sample types effortlessly with the latest Bionano SP DNA prep kits.

These kits excel at purifying Ultra-High Molecular Weight (UHMW) DNA from tissues, tumors, bone marrow aspirate (BMA), blood, cells, as well as various plant and animal tissues. This versatility makes Optical Genome Mapping (OGM) applicable across a wide spectrum of studies and applications, including oncology, constitutional genetic disease research, bioprocessing, and general scientific inquiry.

Bionano’s SP kits necessitate 1.5 * 10^6 cells (for blood, cell lines, and BMA) or 10 – 30 mg of tissue as input. Employing a lyse, bind, and wash process along with novel paramagnetic disks, these kits enable the isolation of UHMW DNA in approximately four hours. This streamlined workflow ensures efficient extraction of high-quality DNA, empowering researchers across various fields to unlock the mysteries of the genome with ease.

Boost your workflow throughput by integrating the efficiency of automation.

Through a pioneering collaboration with the Hamilton Company, Bionano presents the groundbreaking Long String Star V – the world’s inaugural automated platform tailored for the isolation of Ultra-High Molecular Weight (UHMW) DNA.

The Long String Star V stands as an assay-ready workstation, harmoniously designed to complement Bionano’s G2.LS DNA Isolation kits. With this innovative platform, a single operator can seamlessly extract UHMW DNA from up to 24 samples per day, revolutionizing sample processing efficiency while maintaining high-quality results. Experience unparalleled productivity and precision as you propel your research forward with the Long String Star V automation system.

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Stratys

February 19, 2024/in Bionano, Partners/by Harshita Sharma

PRODUCTS

Stratys

Elevate the OGM Sample-to-Report Workflow with the Stratys™ System

Embark on a revolutionary journey towards enhanced workflow speed and simplicity by leveraging the power of Optical Genome Mapping (OGM) combined with the cutting-edge Bionano Stratys™ System. With this innovative approach, break free from the limitations of conventional cytogenetics and sequencing techniques, as you delve into the comprehensive detection of all classes of structural variants. Experience a paradigm shift in genetic analysis, where efficiency and precision converge to unlock new realms of understanding within the genome.

*Lower VAF percentages can be achieved when using the Stratys Plus Chip, which enables up to 1200x genome coverage.

STRATYS CHIPS

Experience unparalleled efficiency and tailored performance with STRATYS CHIPS – your gateway to optimized reagents and consumables for diverse applications. Tailor your journey to results with a versatile array of chips meticulously crafted to align with your unique requirements. Within the STRATYS chips, immerse DNA molecules in a precise nanofluidic environment, where they seamlessly linearize across hundreds of thousands of nanochannels. Through advanced imaging, unravel the intricate genomic architecture and uncover subtle structural variations with unparalleled clarity and accuracy.

STRATYS COMPUTE

Maximize workflow efficiency with STRATYS COMPUTE, your solution for streamlined data processing, ensuring a seamless flow of operations.

Data Processing Powerhouse: Powered by NVIDIA RTX GPUs, STRATYS COMPUTE boasts remarkable processing power, enabling significantly faster runtimes and reduced compute costs. Leveraging cutting-edge technology, software releases drive acceleration, enhancing overall performance.

Support a Constant Flow of Data: Benefit from STRATYS COMPUTE’s advanced technology and intelligent processing, facilitating a continuous stream of data from the Stratys instrument. This ensures optimal scalability of your workflow, maintaining productivity at scale.

Best Sensitivity for OGM: Equipped with the latest informatics pipeline for Optical Genome Mapping (OGM) data, STRATYS COMPUTE delivers unparalleled sensitivity for genome-wide detection of all classes of structural variants (SVs) using OGM technology.

Minimal IT Resources Required: Designed for ease of implementation, the STRATYS COMPUTE workstation can be conveniently installed alongside the Stratys instrument without the need for a dedicated data center. This reduces IT overhead and minimizes implementation time, ensuring a hassle-free setup process.

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Saphyr

February 19, 2024/in Bionano, Partners/by Harshita Sharma

PRODUCTS

Saphyr

Reveal genome-wide structural variation with the Saphyr™ optical genome mapping system.

Consistently identify structural variants across all classes with a resolution as low as 500 base pairs (bp) and a variant allele frequency (VAF) as low as 5% utilizing optical genome mapping (OGM) through the Saphyr™ system. Saphyr™ stands as the foremost tool for detecting structural variants, surpassing the capabilities of next-generation sequencing (NGS) methods and traditional cytogenetic approaches, thus capturing genomic variations often overlooked by these technologies.

Achieve broad, unbiased genomic coverage with flexible data collection.

The Saphyr™ system offers adaptable genomic coverage, enabling the identification of heterozygous or infrequent variants present in mosaic samples and heterogeneous tumors.

In just six hours, obtain a comprehensive 100X coverage of a human genome. To uncover deeper and rarer variants, merely prolong the data collection time on Saphyr™ without incurring additional consumable costs. Achieve an impressive 400X coverage within a 24-hour period, facilitating structural variant (SV) detection down to a 5% variant allele frequency (VAF). Extend runtime further to explore variants with even lower VAF levels.

Enjoy seamless integration and workflow efficiency with the Saphyr™ Chip® consumable and Saphyr™ system.

The Saphyr Chips feature hundreds of thousands of highly parallel nanochannels, which efficiently linearize long, labeled DNA molecules, enabling direct imaging of your samples by the Saphyr instrument.

Sample loading onto the Saphyr Chip is swift and straightforward. Easily pipette up to three samples into individual flow cells on the chip. With the capability to load up to two chips onto the Saphyr instrument per run, achieve a maximum throughput of six samples per operation.

Benefit from the Saphyr instrument and chips’ integration of machine learning-based adaptive loading and automatic run optimization. These features ensure hassle-free scanning and optimize throughput speed, allowing for walk-away operation and the fastest achievable throughput for each run.

Guarantee optimal performance through automated health system monitoring accessible remotely.

The Saphyr™ Assure Service offers an optional (opt-in) automated health monitoring feature, which consistently evaluates data quality and instrument functionality. This feature detects potential issues before they impact data quality and performance, enabling Bionano Support to proactively address any concerns and conduct necessary repairs with minimal downtime.

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Franklin

January 30, 2024/in Genoox, Partners/by Harshita Sharma

PRODUCTS

Franklin

Introducing Franklin – a groundbreaking initiative that seamlessly integrates public data sets with real-world evidence, revolutionizing clinical diagnosis, expediting clinical reporting, ensuring consistent classification, all while fostering a thriving community of genomic professionals and upholding data sovereignty and security.

Impacting Lives at the
Point of Care

Your Gateway to the
Actionable Genome

The Power of
Community

Actionable Insights: With Franklin, genomic professionals can redirect their focus from navigating evidence to delving into actionable insights. Our mission is to construct the most extensive and diverse real-world evidence dataset, unlocking answers to any genomic query through the collaborative power of the community, data, and insights.

Franklin’s Community: Who makes up the Franklin community? Our genomic professionals hail from every facet of the medical genetics domain and span the globe. From genetic counselors, expert physicians, and oncologists to variant scientists, bioinformaticians, clinical geneticists, researchers, and pharmacologists, Franklin unites a diverse array of specialists dedicated to advancing genomic knowledge and practice.

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Our team at Decode Science can help connect you with the experts at Genoox, to arrange a customised demo for your group.

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Your Research

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DNBSEQ-E25

January 29, 2024/in MGI, Partners, Sequencing Platforms/by Harshita Sharma

E25: Sequencing on the Go

Not every sequencing question belongs in a core facility. Whether you’re working at a remote field site, a resource-limited clinic, a teaching lab, or simply need a dedicated benchtop instrument without competing for shared equipment time, the DNBSEQ-E25 puts high-quality sequencing where you need it. Weighing just 15 kg and requiring nothing more than a power source, the E25 integrates microfluidic flow cell technology, CMOS-based detection, and self-luminous dye chemistry into a single compact unit that takes you from loaded sample to FASTQ output — no ancillary hardware, no bioinformatics workstation, no internet connection.

What sets the E25 apart from other portable or benchtop sequencers is the degree to which the entire workflow is self-contained. The built-in computing module handles base calling and report generation on-board, and the enhanced E25A model extends this to full data analysis pipelines for applications including whole-genome sequencing. There’s no washing required between runs, setup takes roughly 10 minutes, and the system supports both MGI and App-C libraries without primer substitutio

But... Why E25?

Specifications

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Supports MGI and App-C libraries and requires no primer substitutions
Reads*	Read Length**	Data Output	Run Time***	Q30****
25 M	SE100	2.5 Gb	5 hrs	>90%
25 M	PE150	7.5 Gb	20 hrs	>80%
* The maximum number of valid reads is obtained by running a specific standard library. Actual performance may vary depending on sample type and library construction method. SE100 consumables can be used for SE50 sequencing; PE150 consumables can be used for PE100 sequencing. Read lengths can be customized in the sequencer user interface. * Run time includes DNB loading and FASTQ generation. Barcode sequencing time is excluded. **** Q30 and run time are averaged across the entire run using a standard library. Actual performance may vary depending on sample type, library quality, insert size, etc.

Product Model

E25, E25A*

Power, Dimensions & Net Weight

Rated Power: 25V DC, 5A
Dimensions (L×W×H): 348 mm × 312 mm × 257 mm
Net Weight: 15 kg

Operating Environment Requirements

Temperature: 15℃–30℃
Relative Humidity: 20% RH – 80% RH
Atmospheric Pressure: 70 kPa – 106 kPa
Pollution Level: Level 2

* For indoor use only.

Why It Matters to You

How You Can Achieve These Results

Considering portable sequencing for your lab or field site?

We can advise on applications, library compatibility, and how the E25 fits into your current workflow. Simply reach out to me.

What our customer says...

Dr Lyman Ngiam (PhD)

Postdoctoral Research Fellow at Centre for Environmental and Agricultural Solutions to Antimicrobial Resistance

"Both E25 and D4 have demonstrated the capability to generate sequencing results within a single day. The prebuilt library preparation protocol and streamlined sequencing workflow make the system highly user-friendly, enabling anyone with piptetting skill to perform sequencing runs with ease.
The simplified operation has significantly reduced preparation time. Notably, the system’s ability to work with low starting DNA concentrations makes it particularly versatile, allowing sequencing of a wide range of sample matrices without the need to obtain high DNA yields beforehand.
Overall, it is an efficient and practical platform, essentially a "load-and-go" system."

MGI Portfolio

DNBSEQ T7+

DNBSEQ-T1+

DNBSEQ-E25

DNBSEQ-G400

DNBSEQ-T7

DNBSEQ-G99

DNBSEQ-G400

January 29, 2024/in MGI, Partners, Sequencing Platforms/by Harshita Sharma

G400: Seamless, Fast, and Precise Sequencing

Most genomics labs don’t run one application — they run many. The DNBSEQ-G400 is designed for exactly this reality. With two independent flow cell slots, two flow cell formats (FCS and FCL), and read configurations spanning SE50 through to PE200 and even SE400, the G400 lets you run different applications simultaneously on the same instrument without compromising on turnaround or data quality. Powered by MGI’s StandardMPS 2.0 reagent chemistry, the platform achieves Q40 accuracy across key read lengths — a level of base-calling precision that reduces error rates and strengthens confidence in variant calls, differential expression, and any downstream analysis where per-base accuracy matters.

What makes the G400 particularly practical for mid-scale genomics operations is the balance between throughput and flexibility. The large flow cell (FCL) delivers up to 1,800M reads and 540 Gb per flow cell at PE150, putting whole-genome sequencing, large RNA-seq experiments, and high-depth exome batches comfortably within reach. Meanwhile, the small flow cell (FCS) supports faster, lower-volume runs — ideal for targeted panels, amplicon sequencing, or urgent turnaround samples — without wasting capacity.

Flexible Enough for Every Application on Your List

Running multiple sequencing applications and need a single platform that handles them all? Our team can walk you through flow cell configurations, throughput planning, and how the G400 fits alongside your existing setup.

Why It Matters to You

For Genomics Core Facilities

Your users submit everything from targeted panels to whole genomes, and they all want results yesterday. The G400’s dual flow cell design lets you batch high-throughput projects on the FCL while running urgent or low-volume jobs on the FCS — simultaneously. Q40 data quality across key read lengths means fewer reruns and higher first-pass success rates, keeping your queue moving and your users satisfied.

For Cancer & Clinical Research Labs

Somatic variant detection demands accuracy. Q40-grade base quality reduces false positive variant calls, particularly at low allele frequencies where sequencing errors and true variants are hardest to distinguish. The G400’s flexible read lengths also let you run tumour-normal WGS, RNA-seq for gene expression, and targeted hotspot panels on a single platform — simplifying your instrument fleet and standardising your data quality.

For Translational & Pharma Research Groups

Drug target validation, biomarker discovery, and companion diagnostic development all require reproducible, high-quality sequencing data across multiple assay types. The G400 supports the breadth of applications these programmes demand — WGS, WES, RNA-seq, methylation, targeted panels — on a single instrument with consistent Q40 performance, reducing the platform-to-platform variability that complicates cross-study comparisons.

For Agricultural & Environmental Genomics

Genotyping-by-sequencing, amplicon panels for pathogen surveillance, metagenomic profiling, and small genome assemblies all fit comfortably within the G400’s output range. The SE400 read mode is particularly relevant for applications requiring longer contiguous reads without moving to a long-read platform. For labs processing high sample volumes across diverse project types, the dual flow cell system keeps throughput high while accommodating varied experimental designs.

Specifications & resources

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Performance by Read Length
Read Length	Data Output/Flow Cell	Data Quality Q30*	Data Quality Q40*	Run Time**
SE50-FCL	75 Gb ~ 90 Gb	>90%	>85%	~14 h
SE100-FCL	150 Gb ~ 180 Gb	>90%	>85%	~25 h
SE400-FCL	600 Gb ~ 720 Gb	>70%	/	~109 h
PE100-FCL	300 Gb ~ 360 Gb	>85%	>85%	~35 h / 38 h***
PE150-FCL	450 Gb ~ 540 Gb	>85%	>85%	~50 h / 56 h***
PE200-FCL	600 Gb ~ 720 Gb	>75%	/	~107 h
SE100-FCS	55 Gb	>85%	/	~13 h
PE100-FCS	110 Gb	>85%	/	~22 h / 26 h***
PE150-FCS	165 Gb	>85%	/	~31 h / 37 h***
* The percentage of bases above Q30 and Q40 is the average from internal standard libraries across the full run. Actual results may vary depending on sample type, library quality, and insert fragment length. Q40 is only achievable with StandardMPS 2.0 reagents.
** Run time is calculated based on dual-slide mode and includes sample loading, sequencing, base calling, and data processing.
*** 35 h, 50 h, 22 h, and 31 h reflect reduced times with the latest system upgrade.

MGI Portfolio

MGISTP-B1000

MGISP-7000

MGISP-3000

MGISP-100

MGISP-NE32

MGIFLP-L50

MGISP-960

MGISP-NEX

MGISP-NE384

MGISP-Smart 8

DNBSEQ-T7

January 29, 2024/in MGI, Partners, Sequencing Platforms/by Harshita Sharma

Turbocharge Your Sequencing with MGI DNBSEQ-T7

High-throughput sequencing projects often stall when data volume, turnaround time, or workflow scalability become limiting factors — especially in whole genome, deep exome, transcriptome, and epigenome studies. Traditional platforms struggle to keep pace, leading to longer runtimes, bottlenecks between runs, and delayed analysis.

DNBSEQ-T7 solves this by delivering ultra-high-throughput sequencing designed specifically for data-intensive genomics.
Built on DNBSEQ™ Technology, it combines advanced biochemical, fluidic, and optical systems to generate up to 6 terabytes of high-quality sequencing data per day, enabling faster completion of large and parallel sequencing projects.

Designed for population-scale studies and production sequencing, DNBSEQ-T7 allows labs to run multiple workflows simultaneously without compromising data quality or consistency. It fits seamlessly into large genomics programs where speed, scale, and sustained performance are critical.

For genomics core facilities and research institutes running high-volume sequencing operations, DNBSEQ-T7 removes throughput constraints and accelerates time to results—without forcing workflow trade-offs.

But... Why T7?

SPECIFICATIONS

Dimensions & Weight

Dimensions (L × W × H): 1656 mm × 903 mm × 1815 mm
Net Weight: 765 kg

Power

Power Type: 200 V~240 V, 50/60 Hz, 30 A
Rated Power: 3000 VA

Floor Bearing Capacity

Over 650 kg/m²

Operational Environment Requirements

Temperature: 19°C~25°C; fluctuation < 2°C per hour
Relative Humidity: 30% RH ~ 80% RH; non-condensing
Atmospheric Pressure: 80 kPa ~ 106 kPa
Waterproof Rating: IPX0
Altitude: Below 2000 meters

Bandwidth for Network Connection

300 Mb/s: For local storage network uploads

Number of Flow Cells : 1-4

Reads : 5800 M

Read Length

PE100:
1. Data Output: 1 – 4 Tb
2. Run Time: 20 – 22 hr
3. Q30: >85%
PE150:
1. Data Output: 1.5 – 6 Tb
2. Run Time: 24 – 30 hr
3. Q30: >85%

The maximum number of effective reads is based on the sequencing of an internal standard library. Actual output may vary with sample types and library preparation methods.

Run time includes DNB loading, sequencing, and base calling. The percentage of base above Q30 is the average of an internal standard library over the entire run. The actual performance is affected by factors such as sample type, library quality, and insert fragment length.

The DNBSEQ sequencing platforms are for Research Use Only. Not for use in diagnostic procedures.

DNBSEQ-T7 (CE-IVD)

Product Code: 900-000241-00

DNBSEQ-T7RS

Product Code: 900-000242-00

For guidance on integrating T7 into your research, Decode Science can provide personalised support and local assistance. Simply reach out to me.

RESOURCES

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MGI Portfolio

Author Archive for: Harshita

About Harshita Sharma

Entries by Harshita Sharma

Evercode WT Mini

10K CELLS

12 SAMPLES

EXPONENTIALLY SCALABLE

NO INSTRUMENT REQUIRED

UNMATCHED DATA QUALITY

WORKS WITH FIXED CELLS AND NUCLEI

Let’s Find You an Application That Helps Your Research

OGM Data Services

HOW IT WORKS

COMPARISON ANALYSIS

Let’s Find You an Application That Helps Your Research

Compute Solutions

Let’s Find You an Application That Helps Your Research

Sample Preparation Kits

Let’s Find You an Application That Helps Your Research

Stratys

500 bp

5%

12 Samples

1200x

Let’s Find You an Application That Helps Your Research

Saphyr

Let’s Find You an Application That Helps Your Research

Franklin

Impacting Lives at the Point of Care

Your Gateway to the Actionable Genome

The Power of Community

Let’s Find You an Application That Helps Your Research

Truly Portable Sequencing

Integrated Detection, No Optical System Required

Sample to Report — No External Computing

Download brochure instantly...

Product Model

Power, Dimensions & Net Weight

Operating Environment Requirements

Ebru Boslem

What our customer says...

Contact Decode Science Today

Q40 Data Quality as Standard

Dual Flow Cell, Dual Application Flexibility

C. Read Length Versatility from SE50 to SE400

D. Production-Ready Throughput in a Manageable Footprint

Chris Wicky

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Reads Per Run

Samples

Read Lengths

DNBSEQ-T7 (CE-IVD)

DNBSEQ-T7RS

Ebru Boslem

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