Entries by Harshita Sharma

Comparison of Evercode™ WT v3 and Chromium™ GEM-X Single Cell 3’ Kit v4 in Mouse Brain Nuclei

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    Comparison of Evercode™ WT v3 and Chromium™ GEM-X Single Cell 3’ Kit v4 in Mouse Brain Nuclei

    Comparison Highlights

    1. Evercode WT v3 delivers superior gene detection in head-to-head sensitivity tests.
    2. Cell type proportions remain consistently represented.
    3. Analysis of differential gene expression shows Evercode WT v3 identifies 2× more genes than competing methods.

    WT-vs-Gem-x-mouse-brain-tech-note-experimental-design-1536x546

    Study Overview
    Two embryonic mouse brains were sagittally dissected and flash-frozen by a third-party vendor.
    One half from each brain was processed by a 10x Genomics certified provider for nuclei isolation and library preparation, while the other halves were processed by Parse Biosciences using their own workflow.
    Sequencing was performed by a third-party, and data analysis was completed using each manufacturer’s respective pipeline.



    View tech Note

    Dr. Ebru Boslem

    ANZ Market Manager - Research Genomics

    As the official distributor in Australia and New Zealand, Decode Science makes accessing genomics solutions straightforward. Our role is to connect your lab with advanced technologies, ensuring you get the right solution for your sequencing projects—delivered locally with support when you need it.



    Get In Touch Today

    Optimized CRISPR/Cas9 Gene Knockout PDF

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    Accelerate knockout experiments with XDel’s next-generation CRISPR design.

    EditCo Bio’s XDel technology eliminates the need for guide RNA pre-screening, using a coordinated multi-gRNA design that delivers consistently high on-target editing across immortalized, primary, and iPSC lines. Validated through 768 edited samples and 4,816 NGS libraries, XDel achieves robust knockout efficiency while minimizing off-target effects—saving time and improving reproducibility across diverse cell types.

    Validated performance. Proven precision.
    With a standardized amplicon sequencing QC workflow and high-throughput automation, XDel enables scalable, high-confidence Cas9-mediated editing for both pooled and single-cell clone analysis. Download the full guide to explore the data, workflows, and results behind EditCo Bio’s high-efficiency gene knockout strategy.

    Optimized CRISPR/Cas9 Gene Knockout pdf EditCo Bio

    Unlock to Download Sheet




      Download Now >

      Hamza Hassan

      Business Development Manager

      As the official distributor in Australia and New Zealand, Decode Science makes accessing genomics solutions straightforward. Our role is to connect your lab with advanced technologies, ensuring you get the right solution for your sequencing projects—delivered locally with support when you need it.



      Get In Touch Today

      Excel Sheet: STOmics Validated Tissue List

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      STOmics Validated Tissue List

      Our STOmics validated tissue list provides researchers with a comprehensive reference of hundreds of tissue types successfully tested using Stereo-seq, the cutting-edge spatial transcriptomics technology. Each tissue entry includes detailed sample information, experimental parameters, and test results, allowing scientists to make informed decisions before starting their single-cell or spatial transcriptomics experiments. By consulting this list, you can ensure compatibility with your tissue samples and streamline your experimental design.

      The list not only highlights tissue types that have been validated but also provides insights into the experimental conditions that yielded the most reliable results. Researchers can leverage this information to optimize sample preparation, sequencing protocols, and data quality control measures. This reduces trial-and-error, saves valuable time and resources, and ensures reproducibility across studies. It is an essential tool for anyone planning to use Stereo-seq for spatial gene expression profiling.

      In addition, our STOmics validated tissue list supports better planning for large-scale studies and comparative analyses. By providing a centralized reference for tissue performance, it helps guide tissue selection, anticipate potential challenges, and maximize experimental success. Whether you are exploring new tissue types or scaling up existing workflows, this validated tissue list is your key resource for robust, high-quality spatial transcriptomics research.

      STOmics-Validated-Tissue-List

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        Notices:

        The STOmics validated tissue list was generated using standard tissue and sample types, all of which are frozen. Each tissue sample had an area of less than 1 cm² and was sectioned at a thickness of 10 μm. Most experiments were performed using the Stereo-seq Transcriptomics Kit V1.2, with a few using V1.1. Sequencing depth ranged from 1–3 G reads per sample, and data were processed using the Stereo-seq Analysis Workflow (SAW) versions V2.1.0–V5.1.3. Testing was conducted between 2020 and 2022.

        Please note that all test parameters and results are highly dependent on the tissue and sample type. This information should be used as a reference guide to help design and optimize your own experiments, rather than as definitive outcomes for all samples.

        Key parameters included in the list:

        1. MID (K): Bin200_Median_MID in thousands

        2. GENETYPE (K): Bin200_Median_Genetype in thousands

        Dr. Ebru Boslem

        ANZ Market Manager - Research Genomics

        As the official distributor in Australia and New Zealand, Decode Science makes accessing genomics solutions straightforward. Our role is to connect your lab with advanced technologies, ensuring you get the right solution for your sequencing projects—delivered locally with support when you need it.



        Get In Touch Today

        Data Set: Parse 10 Million Human PBMCs in a Single Experiment

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          Scale Single-Cell Research Like Never Before

          Key Takeaways

          1. Analyze 10 million cells across 1,152 samples in a single experiment

          2. Increase statistical power by profiling more cells per sample

          3. Capture detailed cellular responses to perturbations and drug treatments

          10 Million Human PBMCs in a Single Experiment

          Figure 1: Experimental Design Overview
          Approximately 10 million PBMCs from 12 healthy donors were treated with 90 different cytokines in a single GigaLab experiment, covering 1,092 experimental conditions.

          Cells were thawed, washed, and seeded at 1 million cells per well across 12 plates. After 24-hour cytokine treatment, cells were fixed, barcoded, and processed for whole transcriptome sequencing. Libraries were sequenced on the Ultima Genomics platform, achieving ~31,000 reads per cell, with 62.45% cell retention after barcoding.

          Results?

          After data processing with the Parse Analysis Pipeline v1.4.0, integration, and classification, 9,697,974 cells across 18 immune cell types were identified—including rare populations that are typically missed in smaller experiments. Each condition yielded a median of 7,400 cells, enabling high-resolution analysis of immune responses.

          Differential expression analysis identified how cytokines influenced gene activity across cell types. Many cytokines triggered strong transcriptional responses, with over 50 genes upregulated per treatment.

          Figure 2: Single-Cell UMAP Overview
          9,697,974 PBMCs from 12 donors were integrated with Harmony, clustered using Scanpy, and manually annotated, revealing 18 immune cell types present across all donors and experimental conditions.

          Figure 3: Cytokine-Induced Gene Changes
          A heatmap summarizes the averaged number of genes significantly upregulated (log fold change >0.3, p <0.001) for each cell type and cytokine, highlighting which immune cells respond most strongly to specific cytokine treatments.

          Example tutorial vignettes from Parse Biosciences and Fabian Theis’ lab at Helmoltz-Munich:

          Parse 10M PBMC Cytokines Clustering Tutorial
          Joey Pangallo, Efi Papalexi – Parse Biosciences, Seattle, WA
          Step-by-step example of analyzing 10 million PBMCs treated with cytokines using the Evercode workflow. Covers data loading, preprocessing, Leiden clustering, and generating UMAP plots with Scanpy.

          Parse 10M PBMC Cytokines Clustering Tutorial (Downsampled)
          Joey Pangallo, Efi Papalexi – Parse Biosciences, Seattle, WA
          Same workflow as above, starting with a downsampled dataset of 1 million cells. Ideal for quicker exploration or limited CPU memory setups.

          scCODA Parse 10M PBMC Cytokines
          Artur Szałata, Dominik Klein, Soeren Becker, Fabian Theis – Helmholtz-Munich
          Demonstrates analysis of cell proportion changes across 10 million PBMCs. Shows how using the full dataset improves statistical significance of perturbation effects. Based on scCODA, a Bayesian model for compositional single-cell data analysis (Nat Commun 12, 6876, 2021).

          Parse 10M PBMC Cytokines Dask Workflow
          Artur Szałata, Dominik Klein, Soeren Becker, Fabian Theis – Helmholtz-Munich
          Walks through preprocessing the 10M cell dataset using Dask. Loads data chunk-wise to reduce memory use and demonstrates highly variable gene selection for downstream analysis.

          Dataset License: CC BY-NC 4.0 (non-commercial use). Commercial licensing inquiries: support@parsebiosciences.com

          QUICK DOWNLOAD FILES

          10M PBMC 12donor 90cytokines h5ad (212 GB)

          Parse 10M PBMC cytokines clustering tutorial

          Parse 10M PBMC cytokines clustering tutorial on downsampled data

          scCODA Parse 10M PBMC cytokines

          Parse 10M PBMC cytokines Dask workflow

          Dr. Ebru Boslem

          ANZ Market Manager - Research Genomics

          As the official distributor in Australia and New Zealand, Decode Science makes accessing genomics solutions straightforward. Our role is to connect your lab with advanced technologies, ensuring you get the right solution for your sequencing projects—delivered locally with support when you need it.



          Get In Touch Today

          DNBSEQ T7+

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          MGI T7+ 2025

          T7+: Ultra-Fast, High-Throughput Sequencing Without Compromise

          T7+ is an integrated ultra-high-throughput sequencing platform built for labs that demand speed, accuracy, and scale. Leveraging MGI’s DNBSEQ™ Technology and SM2.0 biochemistry, it delivers over 14Tb of high-quality sequencing data in 24 hours, making large-scale genomics projects—from population studies to clinical pipelines—both feasible and efficient. Its 7-in-1 modular design automates the entire workflow, reducing hands-on time and minimizing potential errors.

          Beyond sheer performance, T7+ is engineered with clinical relevance in mind. Its capacity for up to 35,000 whole-genome sequences annually ensures that your lab can meet high-throughput demands without compromising turnaround times. This efficiency directly translates to faster research insights, improved diagnostic workflows, and smoother integration into daily lab operations, helping you focus on what matters most: accurate, actionable genomic data.



          Download Brochure



          >14 Tb/24h ultra-fast sequencing



          7-in-1 automation: prep to analysis



          QUAD-Flow Cells: PE150 & PE100 simultaneous



          Q40 >90% high-quality output



          Ergonomic & modular design



          Smart system with diagnostics & self-healing



          Omni-smart hub guides workflows



          Checkpoint resume for uninterrupted runs

          Learn more about how each feature works as you scroll.

          Watch How T7+ Works

          Why It Matters?

          Every hour matters when precision, speed, and reliability determine outcomes. T7+ addresses these challenges by combining ultra-high throughput, rapid turnaround, and intelligent automation, so you can focus on results rather than processes.

          Ultra-Fast Sequencing

          Ultra-Fast Sequencing:

          The proprietary TDI camera and high-density flow cells deliver over 14 Tb of high-quality data in 24 hours, supporting up to 35,000 whole-genome sequences per year. Large-scale projects can now be completed without bottlenecks.

          Seamless Automation

          Seamless Automation:

          The 7-in-1 workflow integrates DNB preparation, loading, sequencing, waste management, data analysis, and compression. This reduces hands-on time, minimizes errors, and produces ready-to-analyze FASTQ files with Q40 >90%.

          Chris Wicky

          Clinical Genomics Manager - ANZ & Country Manager - NZ

          Get a complete overview of T7+ performance, throughput, workflow automation, and configuration options. For guidance on integrating T7+ into your operations, Decode Science can provide personalized support and local assistance.



          Download Brochure



          OR TALK TO ME DIRECTLY

          Omni Start Hub

          Smart & Intuitive Operation:

          Minimalist design, adjustable screen angles, and the Omni-smart hub guide operations with ease, making daily sequencing as simple as interacting with a smartphone.

          Data compression lossless

          Reliable Data Management:

          Built-in lossless data compression reduces storage and bandwidth needs by up to 5× without compromising accuracy. Intelligent checkpointing ensures sequencing resumes seamlessly after interruptions.

          Empower Multi-Omics

          Versatility for Multi-Omics:

          T7+ supports WGS, spatio-temporal omics, cell-omics, proteomics, epigenomics, transcriptomics, and more, making it adaptable to evolving research and operational needs.

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          FAQs

          What is a TDI Camera?

          A TDI (Time Delay and Integration) camera is a high-performance imaging system used in MGI’s T20×2 ultra-high throughput sequencer to capture fluorescence signals with exceptional sensitivity and speed. Unlike conventional cameras that take static images, a TDI camera continuously scans across the sequencing slide, synchronizing image acquisition with sample movement. This technique integrates multiple exposures of the same area over time, significantly boosting signal strength and reducing noise. In the T20*, the TDI line-scan cameras work alongside a liquid-immersion optical lens and a large field-of-view objective to capture more fluorescence data per unit time with higher resolution. The result is faster, more accurate base identification and greater sequencing throughput — a cornerstone technology enabling MGI’s record-breaking data generation efficiency.

          What is DNBSEQ Technology?

          DNBSEQ is MGI’s proprietary sequencing platform based on DNA Nanoball (DNB) technology. Instead of traditional bridge amplification used by other platforms, DNBSEQ amplifies DNA fragments through rolling circle replication, creating dense, uniform DNA nanoballs that are then arrayed on a patterned flow cell. This approach eliminates amplification errors, reduces duplication rates, and enhances signal precision. Combined with MGI’s two-color fluorescence detection and advanced imaging systems, DNBSEQ delivers high-throughput, low-cost, and highly accurate sequencing results. The platform supports a wide range of applications—from whole genome and single-cell sequencing to metagenomics and oncology research—while offering superior data consistency and scalability compared to conventional NGS systems.

          What is SM 2.0?

          Standard MPS 2.0 (SM 2.0) is MGI’s next-generation sequencing chemistry designed to significantly enhance the accuracy and performance of its DNBSEQ™ platforms. By refining enzyme systems, optimizing fluorescent dyes, and improving data interpretation algorithms, SM 2.0 delivers exceptional sequencing quality—achieving over 85% of bases at Q40, or 99.99% base-calling accuracy. These advancements reduce noise, improve signal clarity, and minimize bias from upstream preparation. As a result, researchers gain higher confidence in detecting low-frequency mutations, SNPs, and InDels across applications such as whole genome sequencing, single-cell studies, and microbiome analysis. In essence, SM 2.0 sets a new industry standard for precision, reliability, and data quality in high-throughput sequencing.

          What happens if there’s a power outage or system interruption during a run?

          T7+ features checkpoint resume technology and proactive fault detection, allowing sequencing to continue without data loss once power or system issues are resolved.

          How much hands-on time is required per sequencing run?

          The 7-in-1 integrated workflow minimizes manual intervention—preparation and monitoring are streamlined, so staff can focus on data analysis rather than instrument operation.

          Can T7+ handle varying sample volumes or project scales?

          Yes. The modular QUAD-Flow Cell system allows independent runs, supporting both small batches and large-scale sequencing without compromising speed or accuracy.

          How easy is it to integrate T7+ into an existing lab workflow?

          The platform is designed to fit seamlessly into existing operations, with smart guidance, automated data processing, and flexible output formats that simplify downstream analysis.

          Ready To Order?

          As the authorised distributor for MGI in Australia and New Zealand, Decode Science makes adopting the T7+ effortless. We connect your lab with MGI’s ultra-high-throughput sequencing technology, helping you implement T7+ for faster, more reliable genomic results—with local support and guidance whenever you need it.



          Get a Quote

          MGI Portfolio

          Twist Oncology – DNA CGP Panel

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          PRODUCTS

          Comprehensive Genomic Profiling for Oncology Research



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          The new Twist Oncology - DNA CGP panel offers 562-gene coverage for complete tumour profiling

          Comprehensive Genomic Profiling (CGP) uses next-generation sequencing (NGS) to evaluate multiple clinically relevant biomarkers within a solid tumor. It provides detailed genomic resolution, enabling the detection of single nucleotide variants (SNVs), insertions and deletions (indels), copy number variations (CNVs), select gene fusions, and key cancer genomic signatures such as tumor mutational burden (TMB) and microsatellite instability (MSI).

          By consolidating this information into a single assay, CGP offers a complete view of a tumor’s molecular profile, reducing the need for multiple tumor-specific panels or separate testing methods.

          Why CGP Matters


          Unified Testing Platform

          Combines samples from all tumor types into a single test platform, enabling efficient batching and streamlined workflow.



          Actionable Insights

          Focuses on clinically and research-relevant information, supporting treatment decisions and drug development strategies.



          Cost-Effective Efficiency

          More efficient and economical than whole-exome sequencing (WES) for oncology, lowering resource use while maintaining comprehensive genomic coverage.

          Chris Wicky

          Clinical Genomics Manager - ANZ & Country Manager - NZ

          If you’d like to see how this fits your current setup, I can walk you through integration options or pilot testing. The new Twist Oncology – DNA CGP Panel provides 562-gene coverage for comprehensive tumor profiling.



          Get In Touch Today

          Twist Tumor DNA CGP Panel

          Enable improved Tx Selection and enhanced Clinical Research 

          Fixed Panel + Customisation Options



          FIXED PANEL

          • 562 genes analyzed for SNVs and hotspot mutations (+39 genes compared to TSO500)

          • Microsatellite instability (MSI) detection across ~50 sites

          • Copy number variation (CNV) analysis for 57 clinically relevant genes

          • Selected fusions and tumor mutational burden (TMB) scoring for complete tumor profiling



          CUSTOMISATION OPTION

          • Add custom biomarkers to differentiate your lab’s testing capabilities

          • Adaptable for specific clinical or research needs

          End-to-End Twist NGS Workflow Compatibility:

          • Library preparations: EF2.0, cfDNA

          • Hybridization solutions with options for software analytics

          • Streamlined workflow for enhanced lab efficiency

          Now available in Australia and New Zealand through Decode Science.

          Example Data Metrics

          Example sequencing QC metrics averaged across data down sampled to 2000x raw coverage (32M 2×150 reads). 4.5 Gb of Data is enough for VAF detections ranging ~2%. Data available upon request.

          Panel target size 2.4 Mb
          Example input 50 ng
          Mean Target Coverage 515x
          On-Target Rate 77%
          Fold-80 Base Penalty 1.32
          Duplication Rate 20%
          Target bases covered >100x 99.5%

          Advantages of Twist Oncology Panel

          CONTENT

          TSO-500 : Content is locked at 523 genes in 2025 and beyond

          Twist CGP : Offers an updated CPG panel of 562 genes with Twist dsDNA probes

          CUSTOMISATION

          TSO-500 : Not Possible

          Twist CGP : Can easily modify content to add genomic features or new biomarkers

          COMPATIBILITY

          TSO-500 : Product is locked into Illumina Platform Ecosystem

          Twist CGP : Twist can enable Illumina short-read platforms and non-Illumina platforms (Ultima, Element, etc.)

          WORKFLOW

          TSO-500 : Requires an overnight capture + 2nd Hybridization Capture

          Twist CGP : Single overnight hybridization capture (Option Trinity on Element)

          COMPETITIVE PRICING

          TSO-500 : High cost per sample for IVD kit pricing

          Twist CGP : Can offer competitive pricing and modular kit options.

          MODULAR PRODUCT

          TSO-500 : Purchase is an all inclusive kit, no option for purchasing components

          Twist CGP : Twist can sell modules, or custom configurations through OEM services

          Customer Testimonial

          "At LifeStrands Genomics Australia, we rely heavily on Twist’s NGS probes and reagents across nearly all our assays... Twist’s probe design flexibility and scalability have allowed us to tailor both DNA and RNA panels that suit a wide range of solid tumours without compromising sensitivity or turnaround times. We view Twist not just as a vendor, but as a strategic partner in advancing precision oncology."
          Dr. Vivek Rathi, MD MSc FRCPA
          Medical Director LifeStrands Genomics Australia (Genoox User)

          Ready To Order?

          As the official distributor for Twist Bioscience in Australia and New Zealand, Decode Science makes accessing CGP Panel straightforward. Our role is to connect your lab with Twist’s advanced technologies, ensuring you get the right custom panel solution for your sequencing projects—delivered locally with support when you need it.



          Get a Quote

          DNBSEQ-T1+

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          Accelerate high-throughput genomic testing with DNBSEQ-T1+

          The DNBSEQ-T1+ is one of the fastest T-level benchtop sequencers available globally—built on MGI’s proven DNBSEQ™ technology for accuracy, scalability, and reliability. Designed for clinical and translational genomics labs, the T1+ supports dual flow cell operation, delivering up to 1.2 terabases (Tb) of sequencing data within 24 hours (600 Gb per flow cell).

          For laboratories managing time-sensitive or high-volume projects, this means faster turnaround, improved workflow efficiency, and reduced dependence on external bioinformatics infrastructure. The optional integrated bioinformatics module enables automated secondary analysis immediately after sequencing, helping clinicians and molecular pathologists move from raw data to interpretable results without delay.

          In practice, DNBSEQ-T1+ helps streamline comprehensive genomic profiling (CGP), oncology testing, and clinical research pipelines—supporting both diagnostic accuracy and operational consistency across runs.


          High-Speed, High-Throughput Sequencing

          Generate up to 1.2 Tb of data in a single run with dual flow cell operation.

          Choose from FCL, FCM, or FCS flow cells to match your throughput needs—from small clinical batches to large oncology cohorts.

          Maintain >93% Q30 and >90% Q40 base quality across read lengths up to PE150.

          Complete full runs in as little as 7–24 hours, supporting faster reporting and clinical turnaround.



          Versatile Applications Across Clinical Genomics

          Flexible read lengths (SE50–PE300) suit NIPT, RNA-Seq, oncology panels, WES, WGS, and methylation studies.

          Supports coverage depth from 1 Gb to 120 Gb per sample, enabling both targeted assays and whole-genome workflows.

          Ideal for translational and precision medicine—from pathogen detection to tumour profiling.



          Integrated DNB Make & Load Technology

          DNB M&L (Make & Load) module automates DNB preparation and loading directly within the sequencer.

          Delivers consistent, contamination-free results with minimal hands-on time.

          Each flow cell operates independently, supporting different read lengths or applications in parallel.

          Enables an end-to-end “Make–Sequence–Analyse” workflow that saves time and reduces error.



          Smart Configurations and Automated Analysis

          Available in two setups: DNBSEQ-T1+ RS (flexible throughput) and T1+ ARS (with built-in bioinformatics).

          The ARS configuration automatically triggers advanced data analysis post-run, streamlining bioinformatics pipelines.

          Simplifies data interpretation for clinicians and molecular pathologists, improving workflow efficiency and diagnostic accuracy.

          Chris Wicky

          Clinical Genomics Manager - ANZ & Country Manager - NZ

          Download the DNBSEQ-T1+ brochure for a complete overview of performance metrics, application data, and configuration options. For guidance on how this platform fits your lab’s workflow, Decode Science can walk you through integration and local support options.



          Download Brochure



          OR TALK TO ME DIRECTLY

          Watch How T1+ Works

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          FAQs

          How can the DNBSEQ-T1+ support my existing oncology or CGP workflows?

          The T1+ integrates seamlessly into oncology and comprehensive genomic profiling (CGP) pipelines, providing the depth and coverage needed for both solid tumour and liquid biopsy applications. With PE150 read lengths and up to 1.2 Tb per run, it supports multi-sample batching without compromising turnaround time.

          What data quality can I expect for clinical reporting?

          Across all flow cell types, >93% of bases exceed Q30 and >90% exceed Q40, ensuring high-confidence variant detection for SNVs, indels, CNVs, and fusions. This level of consistency reduces the need for re-runs and strengthens the reliability of reported results.

          How fast can I expect sequencing results for patient samples?

          Depending on the mode, runs complete within 7–24 hours, with automated secondary analysis available immediately post-run on the T1+ ARS configuration. This supports faster clinical reporting and improved patient turnaround.

          Does the DNBSEQ-T1+ simplify lab workflows or require extra setup?

          The DNB Make & Load module automates DNB preparation within the sequencer, reducing manual steps, contamination risk, and hands-on time. Most labs can run end-to-end sequencing with minimal intervention after library prep.

          Can I run different assays on the same instrument?

          Yes. Each flow cell operates independently, allowing different read lengths or applications—for example, running oncology panels alongside RNA-Seq or WES on the same instrument without downtime.

          Ready To Order?

          As the authorised distributor for MGI in Australia and New Zealand, Decode Science makes adopting the DNBSEQ-T1+ effortless. We bridge your lab with MGI’s high-throughput sequencing technology, helping you implement the T1+ for faster, more reliable genomic insights—supported locally whenever you need it.



          Get a Quote

          MGI Portfolio

          G99

          T7

          G400

          E25

          High Throughput Antibody Production

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          PRODUCTS

          High Throughput Antibody Production



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          Introducing CHO and HEK293 Antibody Production

          Twist Bioscience helps researchers speed up antibody discovery with Express Antibody Production using CHO and HEK293 expression systems. Our high-throughput antibody production platform can generate anywhere from dozens to thousands of antibodies, enabling efficient antibody screening for binding specificity and biophysical properties.

          By leveraging Twist’s end-to-end gene-to-protein workflow, you can eliminate common antibody production bottlenecks—saving valuable time and research costs. Starting with Twist Express Genes ensures faster production times and antibodies built entirely from your custom gene sequences.

          Key Features

          CHO Express Antibodies

          1. From 13 business days*
          2. 1 mL and 8 mL scales available
          3. Average Yields = 640 ug



          Start Order

          HEK293 Express Antibodies

          1. From 10 business days*
          2. 1 mL and 8 mL scales available
          3. Average = Yields 760 ug



          Start Order

          Why Twist for Antibody Production?


          Customization

          Design antibodies with optimal binding affinity, specificity, and reduced immunogenicity.



          Speed & Efficiency

          Rapid, sequence-perfect DNA synthesis accelerates your antibody development timeline.



          Scalable Production

          From small-scale studies to large-scale drug discovery, scale antibody production with ease.



          Cutting-Edge Technology

          Access the latest gene synthesis innovations without high costs.



          Expert Support

          Get 24/7 guidance from antibody design to submission.

          You design it. We build it.

          IgG Workflow - Antibody Production

          What Scientists Have to Say

          Wyatt McDonnell

          CEO & Founding Scientist • Infinnimune

          Using Twist’s solutions saves us hundreds of thousands of dollars annually in labor costs. The cost efficiency of Twist Express Antibodies allows us to test four times as many antibodies each year as we otherwise could.

          Dr. Ahuva Nissim

          Professor in Antibody and Therapeutic Engineering • Queen Mary University of London

          Working with Twist…was a great experience…[Twist’s] support was amazing. We have performed the first validation selections which looks promising…

          Pierre Martineau

          Deputy Director, Cancer Research Institute of Montpellier • Founder and Scientific Advisor, iMAb

          We have performed the first selections using the Fab and scFv libraries. No problem in both cases, we got clones and some look really promising.

          Ready To Order?

          Our team can help you in placing the order. Click below to get a quote and fast ordering.



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          Know More About...

          Cyto-Mine® Chroma

          Cytomine Sphere Bio - Decode Science

          Cyto-Mine®

          Have a question?

          Get a call from your local Decode Science representative to help you find the best fit genomics products for you.


            Or give us a call at:

            1300 581 991

            Cinical Oncology Has new

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            Clinical Blog Update

            Updated: Clinical & Pracsoft version 4.3 upgrade and performance improvement tips

             

            From 5 December 2024, Services Australia will no longer support AIR uploads from Clinical V4.2 or earlier.

            Over 60% of MedicalDirector Clincial customers are now using version 4.3

            We understand that some practices may have encountered challenges when upgrading to Clinical and Pracsoft version 4.3. To help, we’ve compiled a list of suggested actions for your organisation’s System Administrator or IT provider to work through.

            If you haven’t upgrade to 4.3 yet, time is running out to remain compliant for AIR uploads from 5 December 2024.  Here are some of the other features you’ll benefit from when you upgrade to Clinical & Pracsoft 4.3:

            • Emails can now be sent with PDF attachments, can be password protected and can be sent directly from the patients file
            • Revamped Smartbar (formally Sidebar) with the latest Smart Connect Care tools
            • Add Progress Notes from anywhere in the patient workflow, via a new floating panel
            • Record a patient’s gender identity and preferred pronouns
            • A growing range of intelligent tools and marketplace partners appearing within the Smartbar

            Learn more and upgrade today

            Clinical and Pracsoft version 4.3 IT performance check list

            These configurations are important for running software upgrades reliably and may also help improve overall performance, which can be affected by frequent scanning or blocking of MedicalDirector software activity by your IT environment’s rules and configuration.

            This broad overview is applicable to a variety of software and hardware scenarios, however should not be considered an all-encompassing solution for your specific healthcare setting. These resources attempt to cover the range of different firewall and antivirus applications available, each with their own method of handling exceptions for permitted files, folders and communications activity.

            The procedures outlined for handling exceptions align with industry standards, where software vendors are expected to advise which Ports and URLs need to be accessible, and the site’s Systems Administrator is responsible for interpreting the requirements and applying them appropriately within the context of the environment they are responsible for.

            We strongly recommend seeking assistance with configuring your specific firewall and antivirus software by consulting your organisation’s Systems Administrator or IT provider.

            CRISPR Reagents Products from EditCo - Decode Science

            Let’s Find You an Application That Helps
            Your Research

            Get a call from your local Decode Science representative to help you find the best fit genomics products for you.


              Or give us a call at:

              1300 581 991

              Arrayed gRNA Libraries

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              PRODUCTS

              Arrayed gRNA Libraries

              Arrayed gRNA Libraries

              Smarter, Faster, and More Efficient CRISPR Screening

              Achieve unparalleled knockout efficiency with EditCo’s multi-guide CRISPR design. Our Arrayed CRISPR gRNA Libraries eliminate the inefficiencies of traditional loss-of-function screens, offering a reliable and ready-to-transfect solution. With up to three spatially coordinated sgRNAs per gene, our approach ensures higher knockout success, reduces false negatives, and eliminates the need for complex NGS data analysis. Designed for both human and mouse genes, our libraries provide fast delivery, robust quality control, and seamless Sanger sequencing analysis—so you can focus on results, not troubleshooting.



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              Whole Genome CRISPR Libraries for Comprehensive Gene Editing

              EditCo’s Whole Human and Whole Mouse Genome Libraries provide unmatched gene coverage with our multi-guide design, ensuring high editing efficiency across 20,000+ gene targets. Designed for seamless transfection, these libraries reduce false negatives and eliminate time-consuming preparation, making large-scale CRISPR screening easier than ever.

              • – Comprehensive Coverage: Target the entire human or mouse genome with high knockout efficiency.
              • – Ready-to-Use Libraries: Pre-plated and transfection-ready, minimizing preparation time.
              • – Enhanced Stability: Chemically modified sgRNAs resist degradation and prevent immune responses.
              • – Flexible Formats: Available in 96- or 384-well plates with multi-guide sgRNAs for reliable gene disruption.

              Accelerate Target Discovery with Pathway Libraries

              EditCo’s 30+ Pathway Libraries, including druggable targets, GPCRs, kinases, and immuno-oncology genes, provide a powerful tool for target identification studies. Designed with our multi-guide CRISPR strategy, these libraries ensure high knockout efficiency and fewer false negatives. Select libraries ship in as little as one week, helping you start your screen faster.

              • – Diverse Pathway Coverage: Includes key gene sets for drug discovery and functional studies.
              • – Fast Shipping: Select libraries ready to ship within a week.
              • – High-Efficiency Knockouts: Multi-guide sgRNAs deliver precise, predictable gene disruption.
              • – Ready-to-Use Format: Available in 96- or 384-well plates with modified sgRNAs for stability.

              Available Gene Pathways

              Optimal Knockout Efficiency for High-Throughput Screening

               

              XDel technology delivers precise, high-efficiency knockouts by using a multi-guide RNA strategy that ensures consistent and reliable gene editing. Unlike traditional single-guide methods, XDel induces fragment deletions in early exons, maximizing on-target accuracy while minimizing variability and off-target effects.

              • Superior editing efficiency – Multi-guide design achieves higher and more consistent knockouts
              • Reduced off-target effects – XDel minimizes unintended edits compared to single-guide methods
              • Sustained knockout effects – Gene edits remain stable across multiple cell passages
              • High viability & protein depletion – Maintains cell health while ensuring effective functional knockouts

              Achieve robust genotype and phenotype screening with XDel’s optimized CRISPR knockout technology.

              XDel multiple gRNA creates fragment deletions

              Image: XDel multiple gRNA creates fragment deletions

              Image: XDel design includes up to 3 modified sgRNAs (grey bars) that target a single gene of interest

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              Gene Knockout kits

              Arrayed gRNA Libraries

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