Entries by Harshita Sharma

Knockout Immortalized Cells

PRODUCTS

Knockout Immortalized Cells

Knock-in Immortalized Cell Lines

Reliable, Reproducible CRISPR Editing for Breakthrough Discoveries

Spend Less Time on Editing, More on Innovation: EditCo’s advanced automation eliminates time-consuming steps, allowing you to focus on impactful research.

Superior Performance & Scalability: Our CRISPR platform delivers high knockout efficiencies, ensuring consistent, reproducible results across experiments.

EditCo Knockout Immortalized Cells

Characterize Genes Associated with Neurodegenerative Disease:

Develop immortalized cell line models to uncover and characterize genes involved in Parkinson’s Disease.

Investigate a Protein’s Mechanism of Action:

Accelerate your data generation with high-quality reagents that avoid high off-target issues to quickly and confidently confirm protein function.

Expedite Drug Discovery
Research:

Validate a new drug lead without having to invest time learning or optimizing CRISPR.

Thoroughly Confirm Your Phenotype in Multiple Models in Parallel:

Generate data in time for your next board meeting or publication by running assays in parallel to identify your targets.

XDel Knockout Cell Pools & Clones - EditCo | Decode Science

XDel Knockout Cell Pools & Clones

XDel is an advanced CRISPR knockout tool that eliminates uncertainty in gene editing. Using a groundbreaking guide RNA design approach, it provides highly effective, reliable, and repeatable gene knockouts, enabling researchers to speed up their breakthroughs with assurance.

  • – Higher Efficiency & Consistency: XDel technology ensures superior on-target knockout rates with minimal variability.
  • – Reduced Off-Target Effects: Achieve precise edits with lower unintended mutations compared to single-guide methods.
  • – Validated & Scalable: Persistent protein depletion enables direct use in functional assays, drug discovery, and disease modeling.

CRISPR Knockout Cell Pools & Clones

CRISPR Knockout Cell Pools & Clones

Accelerate your research with high-efficiency CRISPR Knockout Cell Pools & Clones from EditCo. Our cell pools provide a mix of edited and unedited cells for immediate assays, while clonal lines ensure precise gene knockouts with sequence-verified accuracy.

  • – 50%+ knockout efficiency in cell pools
  • – Up to 95% protein knockout for functional validation
  • – Single, double, or triple knockouts available
  • – Comprehensive QC & sequencing reports included

Knockout Cell Libraries – High-Throughput CRISPR Screening Made Easy

EditCo’s Knockout Cell Libraries enable high-efficiency CRISPR screening with over 90% editing success in a ready-to-use 96-well arrayed format. Designed for functional assays and drug target discovery, our libraries eliminate transfection challenges and infrastructure barriers.

  • Multi-guide CRISPR design for precise knockouts
  • High-throughput screening with scalable workflows
  • – Comprehensive QC & sequencing reports included
  • – Compatible with diverse assays for discovery & validation

Knockout Cell Libraries – High-Throughput CRISPR Screening Made Easy

Ready to Order?

Our team can help you in placing the order. Click below to get a quote and fast ordering.

Immortalized Cells Portfolio

Let’s Find You an Application That Helps
Your Research

Get a call from your local Decode Science representative to help you find the best fit genomics products for you.


    Or give us a call at:

    1300 581 991

    Knock-in iPS Cells

    PRODUCTS

    Knock-in iPS Cells

    iPSC_min

    Advanced CRISPR Knock-Ins for iPSC Research

    EditCo’s advanced CRISPR knock-ins empower neuroscience, cardiovascular, and regenerative medicine research by delivering precise edits in iPSCs while maintaining their quality, pluripotency, and integrity. Our high-throughput automated platform ensures fast lead times and high editing efficiencies, allowing you to focus on downstream applications like assay development and differentiation.

    With minimal off-target effects, our platform offers a range of knock-ins, including single nucleotide variants, tags, and small insertions (<100 bp), available in both homozygous and heterozygous states, as well as in clone or pool formats. Trust EditCo’s robust editing process to accelerate your discoveries with artifact-free, reliable CRISPR-edited iPSCs.

    Knock-in Immortalized Cells

    Isogenic Neuronal Lines:

    Create isogenic neuronal lines by reverting disease SNV genotypes to wild type with CRISPR-edited iPSCs.

    Drug Screening:

    Enhance drug screening with gene-corrected control lines for disease-relevant cell types.

    Protein Tagging:

    Tag target proteins to study subcellular localization under endogenous regulation.

    Disease Modeling:

    Model mutations in disease-relevant cell types using high-quality edited iPSCs.

    iPS cells were assessed for standard pluripotency markers

    Image: iPS cells were assessed for standard pluripotency markers, three days post-editing.

    Single-guide RNA Knock-in Cell Pools

    Achieve high-efficiency CRISPR iPSC knock-ins with EditCo’s Knock-in iPS Cell Pools. These pools offer a mix of edited and unedited cells, giving you flexibility for clonal isolation. Our optimized platform ensures precise edits, while you have the option to perform clonal isolation yourself. For those looking for a fully automated process, explore our Knock-in iPS Cell Clones for homogeneity and convenience.

    Features:

    • – Cell Source: EditCo or customer supplied
    • – Available Edits: SNV, Tag, or Insertion
    • – CRISPR Design: Synthetic modified sgRNA, Donor ssODN
    • – Add-ons: QC for pluripotency testing

    Deliverables:

    • Edited cell pools (2 vials with 5 million cells)
    • Regular updates, sequencing data, and comprehensive QC reports

    EditCo ensures robust editing with high efficiency across a variety of iPSC lines, maintaining pluripotency and delivering consistent, reliable results.

    Single-guide RNA Knock-in Cell Clones

    EditCo’s Knock-in iPS Cell Clones provide homogeneous populations derived from single CRISPR-edited cells. Skip the editing and cloning process, and move directly into functional assays with high-quality, reliable clones. We manage the entire CRISPR editing and cloning process, ensuring you receive precise, genetically modified clones for accelerated research.

    Features:

    • – Cell Source: EditCo or customer supplied
    • – Genetic Modifications: SNV, Tag, or Insertion (Homozygous or Heterozygous)
    • – CRISPR Design: Synthetic modified sgRNA, Donor ssODN
    • – Add-ons: Additional clones, QC for pluripotency and karyotype testing

    Deliverables:

    • 2 independent clones with the required knock-in (2 vials of 500,000 cells each)
    • Regular progress updates, sequencing data, and comprehensive QC reports

    EditCo ensures precise SNV editing and delivers reliable, pluripotent clones ready for your downstream applications.

    SNV editing in iPS cell clones

    Image: 100% SNV editing in iPS cell clones.

    Use EditCo’s iPS Cell Lines or Bring Your Own
    EditCo provides iPS cell lines for all engineered cell orders at no extra cost. Alternatively, you can onboard your own cell lines.

    EditCo-supplied cell lines

    * Parental vials available for evaluation prior to booking an edit

    Ready to Order?

    Our team can help you in placing the order. Click below to get a quote and fast ordering.

    IPS Cells Portfolio

    Let’s Find You an Application That Helps
    Your Research

    Get a call from your local Decode Science representative to help you find the best fit genomics products for you.


      Or give us a call at:

      1300 581 991

      Knockout iPS Cells

      PRODUCTS

      Knockout iPS Cells

      Knockout iPS Cells

      Precise and efficient models for cutting-edge disease research.

      EditCo’s cutting-edge CRISPR technology ensures accurate and efficient gene editing while maintaining iPSC quality, pluripotency, and overall cell integrity. Our automated platform, optimized guide design, and superior reagents enable high-efficiency knock-ins and knockouts, minimizing errors and off-target effects. With a focus on delivering reliable and functional gene modifications, our robust process allows researchers to confidently assay gene functions, model diseases, and explore new therapeutic targets.

      Whether you need precise knockouts or complex knock-ins, EditCo’s advanced editing solutions provide the accuracy and consistency required for high-impact scientific discoveries in biomedical research.

      Knock-in Immortalized Cells

      Gene Function Studies:

      Disrupt your target gene to assess its role in a phenotype or cellular function.

      Gene-Disease Linkage:

      Investigate genetic factors in neurodegenerative diseases using edited iPSCs and neuronal cell types.

      Pathway Analysis:

      Knock out genes in your disease pathway. Differentiate cells into disease-relevant types and test for drug targets.

      Target Validation:

      Validate targets in CRISPR-edited iPSCs to confirm gene-disease linkage in cell models.

      Single Guide Pools Results

      XDel Knockout Cell Pools and Clones

      XDel is a CRISPR technology for precise, efficient gene editing. With a unique guide RNA design, it ensures reproducible knockouts without affecting pluripotency or cell integrity, accelerating research in gene function, disease modeling, and drug development.

      • – High Efficiency: Superior editing and consistent knockouts.
      • – Reliable Results: Persistent protein depletion validated through assays.
      • – Reproducibility: Minimized variability for dependable outcomes.

      XDel Knockout Cell Pools & Clones - EditCo | Decode Science

      XDel multiple guide RNA off-target editing efficiency

      Features

      • – Cell Source: EditCo or customer supplied.
      • – Available Edits: Indel, fragment deletion, homozygous, or heterozygous.
      • – Design: Synthetic modified sgRNA.
      • – Add-Ons: Additional clones, testing.
      • – Deliverables: Updates, edited cell pools (2 vials), sequencing data, and QC reports.

      Superior Editing
      XDel offers more consistent and efficient on-target editing than single-guide RNA methods, ensuring reliable results.

      Reduced Off-Target Effects
      XDel delivers lower off-target editing compared to single-guide RNA, ensuring better precision.

      Robust Knockouts
      XDel pools maintain genomic stability, confirmed by karyotyping and PluriTest™.

      How XDel Works
      XDel uses up to 3 coordinated guides for reliable knockouts, offering more consistent edits than traditional single-guide methods.

      XDel pools and clones

      Multi-guide schematic-new

      Ready to Order?

      Our team can help you in placing the order. Click below to get a quote and fast ordering.

      IPS Cells Portfolio

      Let’s Find You an Application That Helps
      Your Research

      Get a call from your local Decode Science representative to help you find the best fit genomics products for you.


        Or give us a call at:

        1300 581 991

        Knock-in Immortalized Cells

        PRODUCTS

        Knock-in Immortalized Cells

        Arrayed CRISPR sgRNA Libraries

        Get CRISPR-Engineered Cell Lines Faster and More Efficiently.

        EditCo’s Knock-in Immortalized Cells provide a fast and efficient way to integrate engineered cells into your research, using automated transfection optimization and RNP-based delivery to ensure high editing success with minimal off-target effects.

        By eliminating the delays and challenges of DIY CRISPR projects, our cost-effective solution enables you to model more genes and variants across multiple cell lines, accelerating your path to discovery without overspending.

        Knock-in Immortalized Cells

        Tag and Quantify Your Protein:

        Easily purify and measure your target protein with
        precise tagging.

        Create a Disease Model:

        Modify genes to introduce or correct mutations for studying disease phenotypes.

        Analyze Gene Regulation:

        Develop reporter cell lines with promoter tags to monitor
        gene activity.

        Uncover Protein Interactions:

        Use affinity tags to map protein-protein interactions and identify key partners.

        Single Guide Pools Results

        Cost-Effective CRISPR Knock-in Cell Pools – Flexible & Efficient

        EditCo’s Knock-in Immortalized Cell Pools provide a high-throughput, budget-friendly solution for introducing precise edits while maintaining a mixed population of edited and unedited cells.

        • – Optimized transfection for high-efficiency knock-ins
        • – Supports SNVs, tags, and large insertions with advanced HDR strategies
        • – Flexible clonal isolation—manage it yourself or opt for our Knock-in Clones
        • – Comprehensive QC & sequencing reports for reliable validation

        Precision-Verified CRISPR Knock-in Clones – Ready for Your Research

        EditCo’s Knock-in Immortalized Cell Clones provide a sequence-verified, clonal population for precise, high-quality knock-ins. Whether modifying SNVs, tagging proteins, or inserting large sequences, our automated isolation process ensures you receive a single-cell-derived clone with your desired edit.

        • – Guaranteed precision with fully validated knock-ins
        • – Endogenous tagging & SNV editing for functional studies
        • – Streamlined delivery with complete QC & sequencing reports
        • – Customizable options including additional clones & intermediate pools

        Skip the complexity—get ready-to-use, precision-edited clones with EditCo!

        Ready to Order?

        Our team can help you in placing the order. Click below to get a quote and fast ordering.

        Immortalized Cells Portfolio

        Let’s Find You an Application That Helps
        Your Research

        Get a call from your local Decode Science representative to help you find the best fit genomics products for you.


          Or give us a call at:

          1300 581 991

          SR-X™ Biomarker Detection System

          PRODUCTS

          SR-X™ Biomarker Detection System

          THE SR-X™ BIOMARKER DETECTION SYSTEM

          The SR-X Ultra-Sensitive Biomarker Detection System leverages advanced Simoa® bead technology to provide researchers with a compact, cost-effective solution for ultra-sensitive biomarker detection. Designed for multiplexing, the SR-X can detect up to four analytes per well with minimal sample volume, optimizing both productivity and sample preservation. A comprehensive range of Simoa assay kits is available, delivering significantly enhanced sensitivity compared to traditional immunoassay methods. This ensures precise detection of biomarkers at both normal and acute levels across various sample types.

          Ultra-sensitive Simoa® Bead Technology

          Dectect multiplex analytes without compromising sensitivity or specificity

          Semi-Automated

          Simple 2-step or 3-step workflow with minimal user intervention

          Convenient

          Compact instrument with built-in touchscreen control and comprehensive data analysis tools

          Flexible

          Simple custom assay development for both protein and circulating nucleic acid detection

          Low-maintenance

          No daily or monthly user maintenance

          Multiplex Measurement of Low-Abundance Circulating Proteins

          The SR-X™ system enables multiplex detection of neurodegeneration biomarkers using the Simoa® bead-based assay. Healthy donor sample readings are presented alongside the lower limit of quantification (LLOQ), indicated by dashed lines, for each assay in its validated matrix.

          Ready to Order?

          Our team can help you in placing the order. Click below to get a quote and fast ordering.

          Quanterix Portfolio

          Let’s Find You an Application That Helps
          Your Research

          Get a call from your local Decode Science representative to help you find the best fit genomics products for you.


            Or give us a call at:

            1300 581 991

            Integrated online ordering portal between Twist Bioscience & Decode Science

            Integrated online ordering portal between Twist Bioscience & Decode Science!

            To streamline the ordering process for your Twist Gene Fragments, Clonal Genes, Oligo Pools, IgG Antibodies and Custom Vector Onboarding, Twist Bioscience has an integrated portal connecting your Twist Bioscience eCommerce account and Decode Science (channel partner for Twist Bioscience in Australia and New Zealand).

            All you need to do is: 

            Open your Twist eCommerce account www.twistbioscience.com, sign in and select what Twist can build for you: 

             

            Enter your own Project Name – (Twist recommend giving meaningful names to projects, if you don’t assign one, Twist will use a default name. You can always change it later)

            Select start a new project

            Upload your sequences, and follow the prompts through on each screen for your selected project for any of Twist’s synthesis services (NGS ordering not currently online yet)

            Navigate through each page, each product has different options etc*

             

            *If you are ordering genes and need to codon optimise your sequences, please select the gene to optimise and then click on “Codon Optimization” button on the top right of the next screen.

            The platform will then navigate you through the various steps involved. If you have difficulties please  contact your Decode team member and they can set up a virtual session to guide you.

            Twist also now have a bulk codon optimisation tool available – Codon Optimization Tool | Twist Bioscience

            Once you have completed all the details for your project follow the pages through to:

            Send Order Request To The Decode Science – this is a quote request that will be emailed directly from Decode Science in AUD and include any discount structure, promotional offers etc.

            *This is not an order, no obligation to purchase until a Purchase Order or Credit Card is provided to Decode Science to proceed with synthesis of your project.



            You will receive email notification that Decode Science has received your quotation request and provided a project number Q-xxxxxx, which can be used to keep track of your orders.


            Decode Science will email you a quote within 24 hours.  If you would like to proceed with the purchase, please request a PO be generated for Decode Science and email through to support@decodescience.com.au.  Credit card payment is also accepted


            Decode and Twist will take care of everything else, and you will receive your Twist DNA order delivered to your lab.

             – Keep track of your orders in your online account

             – Be notified when your order has been dispatched to Decode Science


            If you have any enquiries, please do not hesitate to contact support@decodescience.com.au

            Smash the limits of single cell sequencing with Parse

            Smash the limits of single cell genomics.

            Join us to learn about Parse’s single cell whole transcriptome technology and recently
            launched Evercode V3 Kits. More cells, more samples, more clarity.

            Combinatorial barcoding technology strips away the limitations and frustrations of yesterday’s single cell approach. It ditches the specialized instrument, freeing you to pursue unprecedented discoveries. Unleash the potential of single cell. Decode Science and Parse Biosciences invite you to a seminar discussing the advances in fixation-based single cell transcriptomics including our V3 chemistry, TCR/BCR kits, CRISPR Detect and Gene Capture.

             

            MEET THE SPEAKER

            John received his PhD at Duke University, where he studied cis-regulatory element activation during limb regeneration. He then spent a few years as a postdoc at the University of California, Merced where he studied early organ formation using single-cell genetic and epigenetic approaches. As a Field Application Scientist at Parse Biosciences, John assists scientists with their single-cell genomics experiments, from experimental design, sample preparation, single-cell library workflows, data analysis, and more.

            John’s favorite model organism are zebrafish, both embryos and adults. In his free time John enjoys eating spicy food, and dabbles in growing his own hot chili pepper plants.

            Brisbane

            Date: 8th September 2025

            Seminar : 11:30 AM – 12:30 PM – Translational Research Institute Room 3000


            Sydney - DAY 1

            SEMINAR 1

            Date: 9th September 2025

            Time: 10 AM – 11 AM

            Location:Westmead Institute of Medical Research (hosted by Genomics Core) L2 WIMR: Meeting room C.2.31

             

            SEMINAR 2

            Date: 9th September 2025

            Time: 2 PM – 3 PM

            Location: UNSW (hosted by Ramaciotti) – AGSM Theatre


            Sydney - DAY 2

            SEMINAR 1

            Date: 10th September 2025

            Time: 9:30 AM – 10:30 AM

            Location: VCCRI (Victor Chang Cardiac Research Institute) (hosted by Innovation Centre), Level 4 Boardroom

            SEMINAR 2

            Date: 10th September 2025

            Time: 12:00 PM – 1 PM

            Location: Garvan Institute (hosted by Single Cell Platform) – John Shine Room, Garvan Institute of Medical Research


            Canberra

            Date: 11th September 2025

            Time: 1:00 – 2:00 PM

            Location: JCSMR, ANU Seminar Rooms 1+2


            Melbourne

            SEMINAR 1

            Date: 12th September 2025

            Time: 11:00 AM – 12:30 PM

            Location: WEHI – Genomics Seminar series, Level 7 seminar room


            Adelaide

            SEMINAR 1

            Date: 16th September 2025

            Time: 10:00 AM – 11:00 AM

            Location: Flinders University Health and Medical Research Building (HMRB)

            SEMINAR 2

            Date: 16th September 2025

            Time: 12:30 PM – 02:00 PM

            Location: SAHMRI (South Australian Health and Medical Research Institute)

            Evercode TCR Mega

            PRODUCTS

            Evercode TCR Mega

            1M CELLS

            96 SAMPLES

            Unlock scalable immune profiling capabilities with Evercode™ TCR Mega, empowering you to analyze up to 1 million cells at a time. In the intricate landscape of immunity, comprehensive data is key. With Evercode™ TCR Mega, you can achieve unparalleled resolution in studying TCR clonotype diversity and T-cell states.

            Benefit from the expansive scale of Evercode™ TCR Mega, which offers a host of advantages alongside the wealth of information provided by WT profiles. Whether you’re exploring immune responses, investigating cellular dynamics, or delving into immunotherapy research, Evercode™ TCR Mega equips you with the tools to navigate the complexities of the immune system with confidence and precision.

            EXPONENTIALLY
            SCALABLE

            Evercode's combinatorial barcoding
            enables you to dramatically
            scale up the cells and samples per experiment.

            NO INSTRUMENT
            REQUIRED

            If you have a centrifuge,
            thermal cycler,
            and some pipettes,
            you’re ready to go.

            UNMATCHED DATA QUALITY

            Better detect lowly expressed
            genes and avoid ambient RNA common
            in droplet-based
            single cell sequencing.

            WORKS WITH FIXED CELLS AND NUCLEI

            Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

            Up to 1 million cells in a single experiment

            Experience the power of scale with Evercode. Conduct experiments with up to 1 million cells in a single run, unlocking the immense diversity within the immune repertoire like never before. With Evercode, identify an extensive array of TCR clonotypes, providing unparalleled insights into immune function and response.

            Not only can Evercode detect clonotypes, but it also offers the capability to map them to T cell subtype clusters. By analyzing gene expression profiles from nearly 1 million T cells isolated from PBMCs, Evercode enables the classification of cells into distinct T cell subtypes. This comprehensive approach ensures a deeper understanding of immune dynamics and facilitates more nuanced analysis of immune responses.

            High TCR detection in activated and primary T cells

            Experience outstanding TCR detection in both activated and primary T cells with our cutting-edge profiling techniques. In our investigation, T cells derived from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation through culture for 3 days with CD3/CD28 beads and IL-2 (Activated).

            Our results demonstrate robust TCR detection in both experimental conditions, highlighting the versatility and reliability of our methodology across diverse T cell states. Whether profiling primary T cells or their activated counterparts, our approach ensures accurate and comprehensive characterization of the TCR repertoire, providing invaluable insights into immune responses and cellular dynamics.

            Trust in our advanced profiling techniques to deliver precise and high-fidelity data, enabling a deeper understanding of T cell biology and immunological processes. With our innovative methodologies, delve into the complexities of the immune system with confidence and clarity, paving the way for transformative discoveries in immunology.

            Comprehensive immune repertoire detection

            Immerse yourself in unparalleled detection of the immune repertoire with the Evercode™ TCR kit, meticulously crafted to offer the most comprehensive profile attainable. In a groundbreaking study spanning 8 donors, our kit revealed the identification of nearly 500,000 unique beta chain clonotypes.

            Notably, the majority of these clonotypes were deemed rare, emphasizing the remarkable sensitivity and depth of our detection capabilities. With the Evercode™ TCR kit at your disposal, you gain the ability to unveil the complete spectrum of immune diversity, from commonplace to exceptionally rare clonotypes. This empowers you to delve into the intricacies of immune responses with unparalleled precision and breadth, opening new avenues for exploration and discovery in immunology.

            tcr parse workflow

            Ready to Order?

            Our team can help you in placing the order. Click below to get a quote and fast ordering.

            Let’s Find You an Application That Helps
            Your Research

            Get a call from your local Decode Science representative to help you find the best fit genomics products for you.


              Or give us a call at:

              1300 581 991

              Evercode TCR

              PRODUCTS

              Evercode TCR

              10K CELLS

              12 SAMPLES

              Explore the depths of the immune repertoire with our cutting-edge solution: single-cell TCR profiling combined with whole transcriptome analysis—no additional instrumentation required.

              With our state-of-the-art technology, you can detect TCRs with remarkable sensitivity while simultaneously capturing transcriptome-wide gene expression, including essential T-cell subtype markers. Delve into the intricate cellular landscape and unlock unprecedented insights by examining paired alpha and beta sequences within individual cells.

              This revolutionary approach empowers you to unravel the complex interplay between TCR diversity and gene expression profiles at the single-cell level, providing a holistic understanding of immune responses and cellular heterogeneity. Bid farewell to the constraints of conventional methods and embark on a transformative journey in immunogenomics research with our integrated solution.

              EXPONENTIALLY
              SCALABLE

              Evercode's combinatorial barcoding
              enables you to dramatically
              scale up the cells and samples per experiment.

              NO INSTRUMENT
              REQUIRED

              If you have a centrifuge,
              thermal cycler,
              and some pipettes,
              you’re ready to go.

              UNMATCHED DATA QUALITY

              Better detect lowly expressed
              genes and avoid ambient RNA common
              in droplet-based
              single cell sequencing.

              WORKS WITH FIXED CELLS AND NUCLEI

              Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

              High TCR detection in activated and primary T cells

              Witness exceptional TCR detection in both activated and primary T cells through our state-of-the-art profiling techniques. In our investigation, T cells sourced from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation via culture for 3 days with CD3/CD28 beads and IL-2 (Activated).

              Our findings reveal robust TCR detection in both experimental conditions, underscoring the versatility and dependability of our methodology across various T cell states. Whether profiling primary T cells or their activated counterparts, our approach guarantees precise and comprehensive characterization of the TCR repertoire, offering invaluable insights into immune responses and cellular dynamics.

              Rely on our advanced profiling techniques to deliver meticulous and high-fidelity data, facilitating a deeper comprehension of T cell biology and immunological processes. With our innovative methodologies, explore the intricacies of the immune system with confidence and clarity.

              Comprehensive immune repertoire detection

              Experience unparalleled detection of the immune repertoire with the Evercode™ TCR kit, designed to provide the most comprehensive profile available. In a groundbreaking study encompassing 8 donors, our kit identified nearly 500,000 unique beta chain clonotypes.

              Remarkably, the vast majority of these clonotypes were classified as rare, highlighting the sensitivity and depth of our detection capabilities. With the Evercode™ TCR kit, you can uncover the full spectrum of immune diversity, from common to exceedingly rare clonotypes, empowering you to explore the intricacies of immune responses with unprecedented precision and breadth.

              tcr parse workflow

              Ready to Order?

              Our team can help you in placing the order. Click below to get a quote and fast ordering.

              Let’s Find You an Application That Helps
              Your Research

              Get a call from your local Decode Science representative to help you find the best fit genomics products for you.


                Or give us a call at:

                1300 581 991

                Evercode TCR Mini

                PRODUCTS

                Evercode TCR Mini

                100K CELLS

                48 SAMPLES

                Unlock the complexity of the immune repertoire with our innovative solution: single-cell TCR profiling combined with whole transcriptome analysis—all without the need for additional instrumentation.

                With our advanced technology, you can achieve sensitive detection of TCRs while simultaneously measuring transcriptome-wide gene expression, including crucial T-cell subtype markers. Dive deep into the cellular landscape and gain unparalleled insights by analyzing paired alpha and beta sequences within the same cell.

                This groundbreaking approach empowers you to uncover the intricate interplay between TCR diversity and gene expression profiles at the single-cell level, providing a comprehensive understanding of immune responses and cellular heterogeneity. Say goodbye to the limitations of traditional methods and embark on a new era of immunogenomics research with our integrated solution.

                EXPONENTIALLY
                SCALABLE

                Evercode's combinatorial barcoding
                enables you to dramatically
                scale up the cells and samples per experiment.

                NO INSTRUMENT
                REQUIRED

                If you have a centrifuge,
                thermal cycler,
                and some pipettes,
                you’re ready to go.

                UNMATCHED DATA QUALITY

                Better detect lowly expressed
                genes and avoid ambient RNA common
                in droplet-based
                single cell sequencing.

                WORKS WITH FIXED CELLS AND NUCLEI

                Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.

                High TCR detection in activated and primary T cells

                Experience high TCR detection in both activated and primary T cells with our advanced profiling techniques. In our study, T cells isolated from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation through culture for 3 days with CD3/CD28 beads and IL-2 (Activated).

                Our results demonstrate robust TCR detection in both scenarios, showcasing the versatility and reliability of our methodology across different T cell states. Whether profiling primary T cells or activated counterparts, our approach ensures accurate and comprehensive characterization of the TCR repertoire, providing invaluable insights into immune responses and cellular dynamics.

                Count on our advanced profiling techniques to deliver precise and high-quality data, enabling deeper understanding of T cell biology and immunological processes.

                tcr parse workflow

                Ready to Order?

                Our team can help you in placing the order. Click below to get a quote and fast ordering.

                Let’s Find You an Application That Helps
                Your Research

                Get a call from your local Decode Science representative to help you find the best fit genomics products for you.


                  Or give us a call at:

                  1300 581 991