Redefining Spatial Biology with STOmics Stereo-seq Technology

STOmics delivers the next generation of spatial transcriptomics through its proprietary Stereo-seq (SpaTial Enhanced REsolution Omics-sequencing) platform. As the first and only technology combining centimeter-scale field of view with true nanoscale resolution, Stereo-seq captures the complete molecular landscape of tissues — from whole-organ panoramas down to subcellular details.

Researchers across oncology, developmental biology, and precision medicine are using STOmics Stereo-seq to generate comprehensive spatial omics datasets that connect gene expression, cell morphology, and cell-to-cell interactions in ways never before possible. By merging spatial transcriptomics, proteomics, and pathology on a single platform, STOmics is redefining how scientists visualize biology in space and time.

But... Why Stereo-seq?

STOmics’ proprietary Stereo-seq (SpaTial Enhanced REsolution Omics-sequencing) introduces a new architecture for spatial biology.
Unlike imaging-based or spot-limited platforms, Stereo-seq uses a DNA nanoball (DNB) patterned chip and Coordinate ID (CID) barcoding to capture RNA molecules in situ across the entire tissue section.
Each transcript’s precise position is preserved, then decoded through sequencing on the DNBSEQ™ platform, reconstructing a full spatial transcriptomic map at sub-cellular scale.

This pipeline links gene expression to morphology and microenvironmental context, enabling true multi-omic correlation within the same tissue slice.

DNA Petterned Chip - STOmics

DNB patterned chip

Creates a fixed nanoscale grid for spatial indexing.

CID Sequencing - STOmics

Spatial CID sequencing

Assigns unique coordinate tags to every capture point.

Stere-seq Chip - STOmics

Stereo-seq Chip

In Situ RNA Capture - STOmics

In-situ RNA capture

Immobilizes transcripts without disturbing native structure.

Library Construction & sequencing - STOmics

Library construction & sequencing

Generates high-depth transcriptome data on the DNBSEQ system.

Spatially resolved transcriptomic profiling - STOmics

Spatial profiling & analysis

Reconstructs tissue architecture at single-cell and subcellular resolution.

Applications of STOmics Stereo-seq

The STOmics Stereo-seq spatial transcriptomics platform empowers scientists to analyze where and how genes are expressed within intact tissues. By integrating spatial RNA sequencing, proteomic profiling, and cell morphology, researchers can uncover cellular organization, lineage relationships, and molecular interactions that conventional bulk or single-cell RNA-seq cannot resolve.


Across developmental biology, organ physiology, disease pathology, and comparative evolution, Stereo-seq provides panoramic, high-resolution insight for every stage of discovery.

Detailed Brochures - Instant Download Instant

Stereo-seq OMNI: Unlocking Spatial Transcriptomics in FFPE Samples

The Stereo-seq OMNI for FFPE Solution is a groundbreaking spatial transcriptomics platform that enables true single-cell total RNA profiling from challenging FFPE samples. Using an innovative Random Probe design, it delivers precise, species-agnostic RNA capture across continuous tissue areas up to 10 mm × 10 mm. Combining histology with high-resolution gene expression data, Stereo-seq OMNI empowers researchers to explore tissue architecture, host–microorganism interactions, and cellular diversity with unprecedented depth and spatial accuracy.

Stereo-seq OMNI

Stereo-CITE V1.1: Spatial Proteo-Transcriptomics at Subcellular Resolution

The Stereo-CITE V1.1 Proteo-Transcriptomics Solution enables simultaneous, in situ analysis of the whole transcriptome and 100+ proteins on the same tissue section with subcellular resolution. By combining CITE-seq with the high-resolution Stereo-seq workflow, it delivers unbiased, spatially resolved maps of RNA and protein expression across centimeter-scale tissue areas. With a streamlined “tissue-to-data” pipeline, Stereo-CITE empowers researchers to decode cell phenotypes, interactions, and tissue architecture—driving new insights into tumor microenvironments, immunotherapy, and drug discovery.

Stereo-seq™ Transcriptomics Solution v1.3

STOmics’ proprietary Stereo-seq™ (SpaTial Enhanced REsolution Omics-sequencing) technology enables researchers to explore the transcriptome with unmatched precision. Delivering subcellular resolution and a broad field-of-view, Stereo-seq allows unbiased whole transcriptome profiling from fresh frozen tissue. With validated compatibility across multiple human, mouse, and other tissue types, it empowers single-cell spatial discovery, improved capture efficiency, and advanced multi-omics integration. Stereo-seq v1.3 offers scalable chip sizes, robust analysis with StereoMap software, and high-definition insights into tissue architecture, cellular interactions, and the tumor microenvironment.

Stereo-seq Transcriptomics Solution v1.3

Dr. Ebru Boslem

ANZ Market Manager - Research Genomics

As the official distributor in Australia and New Zealand, Decode Science makes accessing genomics solutions straightforward. Our role is to connect your lab with STOmics’ advanced technologies, ensuring you get the right solution for your sequencing projects—delivered locally with support when you need it.
What Scientists Are Saying About STOmics Stereo-seq
“When I first saw the data, my reaction was ‘Extraordinary’! Because it was the first time we were able to see the single-cell resolution in spatial context… STOmics technology allows us not only to identify different cell types in a tumor, but also allows us to understand where they are sitting, with whom they are talking, and what they are talking.”
Dr. Ankur Sharma
Head of Onco-Fetal Ecosystem Laboratory at the Harry Perkins Institute of Medical Research
"Stereo sequencing is a method that allows us to map the cells in the tissue. With that technique, we can identify every single cell and position these cells in the tissue. This was not possible in the past. It really opens up new possibilities to understand cell-cell communication."
Prof. Jean Christophe Marine
Science Director, VIB - KU Leuven Center for Cancer Biology Full Professor, Dept. of Oncology, KU Leuven, Belgium

STOmics Portfolio

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As the authorised distributor for STOmics in Australia and New Zealand, Decode Science makes it simple to adopt Stereo-seq spatial omics technology in your lab. We connect researchers with STOmics’ single-cell and spatial multi-omics platforms, offering local expertise, technical support, and implementation guidance — so you can move from data to discovery, faster and with confidence.

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