Tag and Quantify Your Protein:
Easily purify and measure your target protein with
precise tagging.
Create a Disease Model:
Modify genes to introduce or correct mutations for studying disease phenotypes.
PRODUCTS
EditCo’s cutting-edge CRISPR technology ensures accurate and efficient gene editing while maintaining iPSC quality, pluripotency, and overall cell integrity. Our automated platform, optimized guide design, and superior reagents enable high-efficiency knock-ins and knockouts, minimizing errors and off-target effects. With a focus on delivering reliable and functional gene modifications, our robust process allows researchers to confidently assay gene functions, model diseases, and explore new therapeutic targets.
Whether you need precise knockouts or complex knock-ins, EditCo’s advanced editing solutions provide the accuracy and consistency required for high-impact scientific discoveries in biomedical research.
Disrupt your target gene to assess its role in a phenotype or cellular function.
Investigate genetic factors in neurodegenerative diseases using edited iPSCs and neuronal cell types.
Knock out genes in your disease pathway. Differentiate cells into disease-relevant types and test for drug targets.
Validate targets in CRISPR-edited iPSCs to confirm gene-disease linkage in cell models.
XDel is a CRISPR technology for precise, efficient gene editing. With a unique guide RNA design, it ensures reproducible knockouts without affecting pluripotency or cell integrity, accelerating research in gene function, disease modeling, and drug development.
Features
Superior Editing
XDel offers more consistent and efficient on-target editing than single-guide RNA methods, ensuring reliable results.
Reduced Off-Target Effects
XDel delivers lower off-target editing compared to single-guide RNA, ensuring better precision.
Robust Knockouts
XDel pools maintain genomic stability, confirmed by karyotyping and PluriTest™.
How XDel Works
XDel uses up to 3 coordinated guides for reliable knockouts, offering more consistent edits than traditional single-guide methods.
Get a call from your local Decode Science representative to help you find the best fit genomics products for you.
Or give us a call at:
PRODUCTS
EditCo’s Knock-in Immortalized Cells provide a fast and efficient way to integrate engineered cells into your research, using automated transfection optimization and RNP-based delivery to ensure high editing success with minimal off-target effects.
By eliminating the delays and challenges of DIY CRISPR projects, our cost-effective solution enables you to model more genes and variants across multiple cell lines, accelerating your path to discovery without overspending.
Easily purify and measure your target protein with
precise tagging.
Modify genes to introduce or correct mutations for studying disease phenotypes.
Develop reporter cell lines with promoter tags to monitor
gene activity.
Use affinity tags to map protein-protein interactions and identify key partners.
EditCo’s Knock-in Immortalized Cell Pools provide a high-throughput, budget-friendly solution for introducing precise edits while maintaining a mixed population of edited and unedited cells.
EditCo’s Knock-in Immortalized Cell Clones provide a sequence-verified, clonal population for precise, high-quality knock-ins. Whether modifying SNVs, tagging proteins, or inserting large sequences, our automated isolation process ensures you receive a single-cell-derived clone with your desired edit.
Skip the complexity—get ready-to-use, precision-edited clones with EditCo!
Get a call from your local Decode Science representative to help you find the best fit genomics products for you.
Or give us a call at:
PRODUCTS
The SR-X Ultra-Sensitive Biomarker Detection System leverages advanced Simoa® bead technology to provide researchers with a compact, cost-effective solution for ultra-sensitive biomarker detection. Designed for multiplexing, the SR-X can detect up to four analytes per well with minimal sample volume, optimizing both productivity and sample preservation. A comprehensive range of Simoa assay kits is available, delivering significantly enhanced sensitivity compared to traditional immunoassay methods. This ensures precise detection of biomarkers at both normal and acute levels across various sample types.
Dectect multiplex analytes without compromising sensitivity or specificity
Simple 2-step or 3-step workflow with minimal user intervention
Compact instrument with built-in touchscreen control and comprehensive data analysis tools
Simple custom assay development for both protein and circulating nucleic acid detection
No daily or monthly user maintenance
The SR-X™ system enables multiplex detection of neurodegeneration biomarkers using the Simoa® bead-based assay. Healthy donor sample readings are presented alongside the lower limit of quantification (LLOQ), indicated by dashed lines, for each assay in its validated matrix.
Get a call from your local Decode Science representative to help you find the best fit genomics products for you.
Or give us a call at:
PRODUCTS
Unlock scalable immune profiling capabilities with Evercode™ TCR Mega, empowering you to analyze up to 1 million cells at a time. In the intricate landscape of immunity, comprehensive data is key. With Evercode™ TCR Mega, you can achieve unparalleled resolution in studying TCR clonotype diversity and T-cell states.
Benefit from the expansive scale of Evercode™ TCR Mega, which offers a host of advantages alongside the wealth of information provided by WT profiles. Whether you’re exploring immune responses, investigating cellular dynamics, or delving into immunotherapy research, Evercode™ TCR Mega equips you with the tools to navigate the complexities of the immune system with confidence and precision.
Evercode's combinatorial barcoding
enables you to dramatically
scale up the cells and samples per experiment.
If you have a centrifuge,
thermal cycler,
and some pipettes,
you’re ready to go.
Better detect lowly expressed
genes and avoid ambient RNA common
in droplet-based
single cell sequencing.
Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.
Experience the power of scale with Evercode. Conduct experiments with up to 1 million cells in a single run, unlocking the immense diversity within the immune repertoire like never before. With Evercode, identify an extensive array of TCR clonotypes, providing unparalleled insights into immune function and response.
Not only can Evercode detect clonotypes, but it also offers the capability to map them to T cell subtype clusters. By analyzing gene expression profiles from nearly 1 million T cells isolated from PBMCs, Evercode enables the classification of cells into distinct T cell subtypes. This comprehensive approach ensures a deeper understanding of immune dynamics and facilitates more nuanced analysis of immune responses.
Experience outstanding TCR detection in both activated and primary T cells with our cutting-edge profiling techniques. In our investigation, T cells derived from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation through culture for 3 days with CD3/CD28 beads and IL-2 (Activated).
Our results demonstrate robust TCR detection in both experimental conditions, highlighting the versatility and reliability of our methodology across diverse T cell states. Whether profiling primary T cells or their activated counterparts, our approach ensures accurate and comprehensive characterization of the TCR repertoire, providing invaluable insights into immune responses and cellular dynamics.
Trust in our advanced profiling techniques to deliver precise and high-fidelity data, enabling a deeper understanding of T cell biology and immunological processes. With our innovative methodologies, delve into the complexities of the immune system with confidence and clarity, paving the way for transformative discoveries in immunology.
Immerse yourself in unparalleled detection of the immune repertoire with the Evercode™ TCR kit, meticulously crafted to offer the most comprehensive profile attainable. In a groundbreaking study spanning 8 donors, our kit revealed the identification of nearly 500,000 unique beta chain clonotypes.
Notably, the majority of these clonotypes were deemed rare, emphasizing the remarkable sensitivity and depth of our detection capabilities. With the Evercode™ TCR kit at your disposal, you gain the ability to unveil the complete spectrum of immune diversity, from commonplace to exceptionally rare clonotypes. This empowers you to delve into the intricacies of immune responses with unparalleled precision and breadth, opening new avenues for exploration and discovery in immunology.
Get a call from your local Decode Science representative to help you find the best fit genomics products for you.
Or give us a call at:
PRODUCTS
Explore the depths of the immune repertoire with our cutting-edge solution: single-cell TCR profiling combined with whole transcriptome analysis—no additional instrumentation required.
With our state-of-the-art technology, you can detect TCRs with remarkable sensitivity while simultaneously capturing transcriptome-wide gene expression, including essential T-cell subtype markers. Delve into the intricate cellular landscape and unlock unprecedented insights by examining paired alpha and beta sequences within individual cells.
This revolutionary approach empowers you to unravel the complex interplay between TCR diversity and gene expression profiles at the single-cell level, providing a holistic understanding of immune responses and cellular heterogeneity. Bid farewell to the constraints of conventional methods and embark on a transformative journey in immunogenomics research with our integrated solution.
Evercode's combinatorial barcoding
enables you to dramatically
scale up the cells and samples per experiment.
If you have a centrifuge,
thermal cycler,
and some pipettes,
you’re ready to go.
Better detect lowly expressed
genes and avoid ambient RNA common
in droplet-based
single cell sequencing.
Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.
Witness exceptional TCR detection in both activated and primary T cells through our state-of-the-art profiling techniques. In our investigation, T cells sourced from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation via culture for 3 days with CD3/CD28 beads and IL-2 (Activated).
Our findings reveal robust TCR detection in both experimental conditions, underscoring the versatility and dependability of our methodology across various T cell states. Whether profiling primary T cells or their activated counterparts, our approach guarantees precise and comprehensive characterization of the TCR repertoire, offering invaluable insights into immune responses and cellular dynamics.
Rely on our advanced profiling techniques to deliver meticulous and high-fidelity data, facilitating a deeper comprehension of T cell biology and immunological processes. With our innovative methodologies, explore the intricacies of the immune system with confidence and clarity.
Experience unparalleled detection of the immune repertoire with the Evercode™ TCR kit, designed to provide the most comprehensive profile available. In a groundbreaking study encompassing 8 donors, our kit identified nearly 500,000 unique beta chain clonotypes.
Remarkably, the vast majority of these clonotypes were classified as rare, highlighting the sensitivity and depth of our detection capabilities. With the Evercode™ TCR kit, you can uncover the full spectrum of immune diversity, from common to exceedingly rare clonotypes, empowering you to explore the intricacies of immune responses with unprecedented precision and breadth.
Get a call from your local Decode Science representative to help you find the best fit genomics products for you.
Or give us a call at:
PRODUCTS
Unlock the complexity of the immune repertoire with our innovative solution: single-cell TCR profiling combined with whole transcriptome analysis—all without the need for additional instrumentation.
With our advanced technology, you can achieve sensitive detection of TCRs while simultaneously measuring transcriptome-wide gene expression, including crucial T-cell subtype markers. Dive deep into the cellular landscape and gain unparalleled insights by analyzing paired alpha and beta sequences within the same cell.
This groundbreaking approach empowers you to uncover the intricate interplay between TCR diversity and gene expression profiles at the single-cell level, providing a comprehensive understanding of immune responses and cellular heterogeneity. Say goodbye to the limitations of traditional methods and embark on a new era of immunogenomics research with our integrated solution.
Evercode's combinatorial barcoding
enables you to dramatically
scale up the cells and samples per experiment.
If you have a centrifuge,
thermal cycler,
and some pipettes,
you’re ready to go.
Better detect lowly expressed
genes and avoid ambient RNA common
in droplet-based
single cell sequencing.
Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.
Experience high TCR detection in both activated and primary T cells with our advanced profiling techniques. In our study, T cells isolated from peripheral blood mononuclear cells (PBMCs) underwent two distinct conditions: direct profiling (Primary) and activation through culture for 3 days with CD3/CD28 beads and IL-2 (Activated).
Our results demonstrate robust TCR detection in both scenarios, showcasing the versatility and reliability of our methodology across different T cell states. Whether profiling primary T cells or activated counterparts, our approach ensures accurate and comprehensive characterization of the TCR repertoire, providing invaluable insights into immune responses and cellular dynamics.
Count on our advanced profiling techniques to deliver precise and high-quality data, enabling deeper understanding of T cell biology and immunological processes.
Get a call from your local Decode Science representative to help you find the best fit genomics products for you.
Or give us a call at:
PRODUCTS
Streamline the scaling of your single-cell projects with Evercode™ split-pool combinatorial barcoding. This innovative technique offers a straightforward, instrument-free solution to single-cell sequencing, revolutionizing the process with its simplicity and versatility.
With Evercode™, you can effortlessly adopt a highly sensitive approach to single-cell sequencing, regardless of your lab’s resources or expertise level. The simplicity of this method makes it accessible to researchers of all backgrounds, while still delivering unparalleled sensitivity, scalability, and flexibility.
Say goodbye to complex instrumentation and cumbersome protocols. Evercode™ empowers labs of any size to embark on single-cell sequencing projects with confidence, paving the way for groundbreaking discoveries in cellular biology and beyond.
Evercode's combinatorial barcoding
enables you to dramatically
scale up the cells and samples per experiment.
If you have a centrifuge,
thermal cycler,
and some pipettes,
you’re ready to go.
Better detect lowly expressed
genes and avoid ambient RNA common
in droplet-based
single cell sequencing.
Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.
In a rigorous comparative study conducted on mouse brain samples, Evercode WT v2 demonstrated exceptional superiority over the Chromium Next GEM Single Cell 3’ Kit v3.1. Impressively, Evercode WT v2 detected an average of 84% more genes at a common read depth target of 20,000 reads per cell.
With Evercode WT v2 at your disposal, you gain the power to uncover a broader spectrum of genes and dive deeper into gene expression profiles. This invaluable wealth of information will enrich your research endeavors, providing nuanced insights into cellular dynamics and molecular processes. Elevate your single-cell transcriptomics studies to unprecedented heights with the unmatched sensitivity and precision offered by Evercode WT v2.
Evercode™ sets a new standard by delivering more results per experiment compared to leading droplet-based technologies. This means that with Evercode™, you can achieve your research goals with significantly fewer experiments, saving time, resources, and effort.
By maximizing the efficiency of each experiment, Evercode™ allows you to generate more data and insights in less time. Whether you’re exploring gene expression profiles, investigating cellular heterogeneity, or uncovering novel biological pathways, Evercode™ streamlines the process and accelerates your research progress.
With Evercode™, you can optimize your experimental workflow and achieve more impactful results with fewer resources expended. Experience the difference that Evercode™ can make in advancing your scientific discoveries and pushing the boundaries of single-cell analysis.
Our innovative technology allows you to fix cells or nuclei as soon as they’re available, effectively preserving the biological integrity until you’re ready to proceed with your experiments. With just a 30-minute fixation process, your samples remain stable for up to 6 months.
This approach offers unparalleled flexibility in your research workflow. Whether you’re conducting a timecourse study, collaborating across multiple laboratories, or need to segregate sample preparation from core lab space, fixation provides the freedom to work according to your schedule and preferences.
With Evercode™, you can confidently lock in the biology of your samples, knowing that they’ll be ready for analysis whenever you are. Say goodbye to time constraints and logistical challenges – embrace the flexibility of fixation with Evercode™.
Get a call from your local Decode Science representative to help you find the best fit genomics products for you.
Or give us a call at:
PRODUCTS
Realize your single-cell aspirations with Evercode™ split-pool combinatorial barcoding. This straightforward, instrument-free solution revolutionizes single-cell sequencing, offering unparalleled sensitivity, scalability, and flexibility to labs of any size.
With Evercode™, you can effortlessly adopt a highly sensitive approach to single-cell sequencing, empowering you to unlock the complexities of cellular heterogeneity with ease. Scale your experiments to new heights while maintaining precision and reliability, thanks to Evercode’s adaptable design and seamless workflow.
Say goodbye to cumbersome instrumentation and complex protocols – Evercode™ simplifies single-cell sequencing, making it accessible to researchers at all levels. Whether you’re exploring the intricacies of developmental biology, investigating immune responses, or unraveling the mysteries of cancer heterogeneity, Evercode™ equips you with the tools you need to achieve your single-cell ambitions.
Evercode's combinatorial barcoding
enables you to dramatically
scale up the cells and samples per experiment.
If you have a centrifuge,
thermal cycler,
and some pipettes,
you’re ready to go.
Better detect lowly expressed
genes and avoid ambient RNA common
in droplet-based
single cell sequencing.
Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.
Embark on a journey of unparalleled sensitivity in gene detection with Evercode WT v2. In a comprehensive comparative study conducted on mouse brain samples, Evercode WT v2 demonstrated remarkable superiority over the Chromium Next GEM Single Cell 3’ Kit v3.1. Remarkably, Evercode WT v2 detected an average of 84% more genes at a common read depth target of 20,000 reads per cell.
With Evercode WT v2 as your tool of choice, you can uncover a broader spectrum of genes and delve deeper into gene expression profiles. This invaluable information will enrich your research endeavors, providing nuanced insights into cellular dynamics and molecular processes. Elevate your single-cell transcriptomics studies to unprecedented heights with the unmatched sensitivity and precision offered by Evercode WT v2.
Elevate signal quality and minimize noise in your single-cell RNA sequencing (scRNA-seq) experiments with Evercode™. Multiplets, a common challenge in scRNA-seq approaches, can complicate data analysis and obscure biological insights. By adopting Evercode™, which utilizes a cell-as-reaction-vessel approach, you can eliminate issues associated with multiplets, leading to cleaner and more accurate data.
In a human-mouse species mixing experiment conducted with Evercode™, we achieved an exceptionally low multiplet rate of only 2.3%. This rate significantly outperforms traditional droplet-based approaches, demonstrating Evercode’s™ effectiveness in reducing multiplet interference and enhancing data quality.
With Evercode™, you can confidently boost signal detection while minimizing noise, enabling more precise and insightful analysis of single-cell transcriptomic data. Say goodbye to multiplet-related challenges and unlock the full potential of your scRNA-seq experiments with Evercode™.
Get a call from your local Decode Science representative to help you find the best fit genomics products for you.
Or give us a call at:
PRODUCTS
Introducing Evercode™ WT Mini V2, the revolutionary solution for single-cell whole transcriptome analysis. Designed to operate without the need for additional instruments, the Evercode™ WT Mini V2 allows you to delve into single-cell transcriptomics with ease and convenience.
Key features include:
Compact Design: The Evercode™ WT Mini V2 is perfectly sized for researchers looking to explore single-cell transcriptomics on a smaller scale. Its compact design makes it ideal for generating proof-of-concept results before scaling up to larger platforms.
Quality Results: Experience the exceptional quality of results achievable with Parse technology. The Evercode™ WT Mini V2 enables you to obtain reliable and accurate transcriptomic data from individual cells, providing valuable insights into your biological samples.
Scalability: As your research progresses, seamlessly transition to larger platforms such as the Evercode™ WT or Evercode™ WT Mega to delve deeper into your biology. The Evercode™ WT Mini V2 serves as an ideal starting point for expanding your single-cell transcriptomics studies.
With Evercode™ WT Mini V2, unlock the potential of single-cell transcriptomics and embark on a journey of discovery in your research. Explore the complexities of gene expression at the single-cell level and uncover new insights into cellular heterogeneity and biological processes.
Evercode's combinatorial barcoding
enables you to dramatically
scale up the cells and samples per experiment.
If you have a centrifuge,
thermal cycler,
and some pipettes,
you’re ready to go.
Better detect lowly expressed
genes and avoid ambient RNA common
in droplet-based
single cell sequencing.
Fix and store samples as they come in for up to 6 months and then run together later on your schedule. Ideal for cross-site collaborations.
Experience unmatched sensitivity in gene detection with Evercode WT v2. In a comparative study conducted in mouse brain samples, Evercode WT v2 outperformed the Chromium Next GEM Single Cell 3’ Kit v3.1, detecting an average of 84% more genes at a common read depth target of 20,000 reads per cell.
With Evercode WT v2, you can uncover a broader spectrum of genes and gain deeper insights into gene expression profiles, providing invaluable information for your research endeavors. Elevate your single-cell transcriptomics studies to new heights with the superior sensitivity of Evercode WT v2
Achieve significantly lower multiplet rates compared to droplet-based approaches with Evercode WT. In a human-mouse species mixing experiment utilizing Evercode WT, we observed an impressively low multiplet rate of only 2.3%. This rate is substantially lower than what is typically encountered with droplet-based methods.
By leveraging Evercode WT, researchers can confidently minimize the occurrence of multiplets, ensuring greater accuracy and reliability in single-cell transcriptomic analysis. This enhanced precision allows for more accurate interpretation of biological data and deeper insights into complex biological systems.
Get a call from your local Decode Science representative to help you find the best fit genomics products for you.
Or give us a call at:
PRODUCTS
USING OGM IN YOUR RESEARCH
Incorporating Optical Genome Mapping (OGM) into your research opens up a realm of possibilities for detecting genome-wide structural variations with unparalleled sensitivity and unbiased analysis. Unlike sequencing-based technologies and conventional cytogenetic techniques, OGM offers a comprehensive and highly sensitive approach to uncovering structural variations within the genome.
By leveraging our services laboratory, you can embark on projects to analyze samples using OGM. Our expert team will guide you through the process, ensuring accurate and reliable results. Whether you’re exploring genetic anomalies in cancer, investigating constitutional genetic disorders, or studying complex genomic rearrangements, OGM provides a powerful tool for uncovering structural variations with precision and efficiency.
With OGM, you can gain deeper insights into the genomic landscape of your samples, leading to breakthroughs in understanding disease mechanisms, identifying potential therapeutic targets, and advancing personalized medicine initiatives. Join us in harnessing the transformative potential of OGM to drive forward your research and uncover the hidden secrets of the genome.
During an Optical Genome Mapping (OGM) research project with our services laboratory, you’ll embark on a collaborative journey with our experienced team.
Here’s how it works:
Through this collaborative approach, we aim to deliver actionable insights that advance your research objectives and drive scientific discovery. Join us in unlocking the full potential of OGM to uncover the mysteries of the genome and accelerate breakthroughs in your field of study.
Structural variants called against GRCh37/hg19 or GRCh38/hg38 will be filtered against a control database or gene list of choice based on the project goals. Dual or trio variant annotation can be run for various applications. These include identifying de novo or inherited variants in germline samples, somatic variants in matched tumor-control samples, and targeted structural variants in edited versus unedited control cell lines. Just indicate the relationship between samples in the intake form.
Get a call from your local Decode Science representative to help you find the best fit genomics products for you.
Or give us a call at:
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